ID   RPAB1_CANGA             Reviewed;         215 AA.
AC   Q6FQA6;
DT   11-OCT-2004, integrated into UniProtKB/Swiss-Prot.
DT   19-JUL-2004, sequence version 1.
DT   25-MAY-2022, entry version 102.
DE   RecName: Full=DNA-directed RNA polymerases I, II, and III subunit RPABC1;
DE            Short=RNA polymerases I, II, and III subunit ABC1;
GN   Name=RPB5; OrderedLocusNames=CAGL0I07799g;
OS   Candida glabrata (strain ATCC 2001 / CBS 138 / JCM 3761 / NBRC 0622 / NRRL
OS   Y-65) (Yeast) (Torulopsis glabrata).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC   Saccharomycetales; Saccharomycetaceae; Nakaseomyces;
OC   Nakaseomyces/Candida clade.
OX   NCBI_TaxID=284593;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 2001 / CBS 138 / JCM 3761 / NBRC 0622 / NRRL Y-65;
RX   PubMed=15229592; DOI=10.1038/nature02579;
RA   Dujon B., Sherman D., Fischer G., Durrens P., Casaregola S., Lafontaine I.,
RA   de Montigny J., Marck C., Neuveglise C., Talla E., Goffard N., Frangeul L.,
RA   Aigle M., Anthouard V., Babour A., Barbe V., Barnay S., Blanchin S.,
RA   Beckerich J.-M., Beyne E., Bleykasten C., Boisrame A., Boyer J.,
RA   Cattolico L., Confanioleri F., de Daruvar A., Despons L., Fabre E.,
RA   Fairhead C., Ferry-Dumazet H., Groppi A., Hantraye F., Hennequin C.,
RA   Jauniaux N., Joyet P., Kachouri R., Kerrest A., Koszul R., Lemaire M.,
RA   Lesur I., Ma L., Muller H., Nicaud J.-M., Nikolski M., Oztas S.,
RA   Ozier-Kalogeropoulos O., Pellenz S., Potier S., Richard G.-F.,
RA   Straub M.-L., Suleau A., Swennen D., Tekaia F., Wesolowski-Louvel M.,
RA   Westhof E., Wirth B., Zeniou-Meyer M., Zivanovic Y., Bolotin-Fukuhara M.,
RA   Thierry A., Bouchier C., Caudron B., Scarpelli C., Gaillardin C.,
RA   Weissenbach J., Wincker P., Souciet J.-L.;
RT   "Genome evolution in yeasts.";
RL   Nature 430:35-44(2004).
CC   -!- FUNCTION: DNA-dependent RNA polymerase catalyzes the transcription of
CC       DNA into RNA using the four ribonucleoside triphosphates as substrates.
CC       Common component of RNA polymerases I, II and III which synthesize
CC       ribosomal RNA precursors, mRNA precursors and many functional non-
CC       coding RNAs, and small RNAs, such as 5S rRNA and tRNAs, respectively.
CC       Pol II is the central component of the basal RNA polymerase II
CC       transcription machinery. Pols are composed of mobile elements that move
CC       relative to each other. In Pol II, RPB5 is part of the lower jaw
CC       surrounding the central large cleft and thought to grab the incoming
CC       DNA template. Seems to be the major component in this process (By
CC       similarity). {ECO:0000250}.
CC   -!- SUBUNIT: Component of the RNA polymerase I (Pol I), RNA polymerase II
CC       (Pol II) and RNA polymerase III (Pol III) complexes consisting of at
CC       least 14, 12 and 17 subunits, respectively. {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the archaeal Rpo5/eukaryotic RPB5 RNA polymerase
CC       subunit family. {ECO:0000305}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; CR380955; CAG60525.1; -; Genomic_DNA.
DR   RefSeq; XP_447588.1; XM_447588.1.
DR   AlphaFoldDB; Q6FQA6; -.
DR   SMR; Q6FQA6; -.
DR   STRING; 5478.XP_447588.1; -.
DR   EnsemblFungi; CAG60525; CAG60525; CAGL0I07799g.
DR   GeneID; 2889008; -.
DR   KEGG; cgr:CAGL0I07799g; -.
DR   CGD; CAL0132208; CAGL0I07799g.
DR   VEuPathDB; FungiDB:CAGL0I07799g; -.
DR   eggNOG; KOG3218; Eukaryota.
DR   HOGENOM; CLU_058320_0_0_1; -.
DR   InParanoid; Q6FQA6; -.
DR   OMA; VRDRGYF; -.
DR   Proteomes; UP000002428; Chromosome I.
DR   GO; GO:0005736; C:RNA polymerase I complex; IEA:EnsemblFungi.
DR   GO; GO:0005665; C:RNA polymerase II, core complex; IEA:EnsemblFungi.
DR   GO; GO:0005666; C:RNA polymerase III complex; IEA:EnsemblFungi.
DR   GO; GO:0003677; F:DNA binding; IEA:InterPro.
DR   GO; GO:0001054; F:RNA polymerase I activity; IEA:EnsemblFungi.
DR   GO; GO:0001055; F:RNA polymerase II activity; IEA:EnsemblFungi.
DR   GO; GO:0001056; F:RNA polymerase III activity; IEA:EnsemblFungi.
DR   GO; GO:0003968; F:RNA-directed 5'-3' RNA polymerase activity; IEA:EnsemblFungi.
DR   GO; GO:0042790; P:nucleolar large rRNA transcription by RNA polymerase I; IEA:EnsemblFungi.
DR   GO; GO:0006363; P:termination of RNA polymerase I transcription; IEA:EnsemblFungi.
DR   GO; GO:0006386; P:termination of RNA polymerase III transcription; IEA:EnsemblFungi.
DR   GO; GO:0006362; P:transcription elongation from RNA polymerase I promoter; IEA:EnsemblFungi.
DR   GO; GO:0006368; P:transcription elongation from RNA polymerase II promoter; IEA:EnsemblFungi.
DR   GO; GO:0006361; P:transcription initiation from RNA polymerase I promoter; IEA:EnsemblFungi.
DR   GO; GO:0006367; P:transcription initiation from RNA polymerase II promoter; IEA:EnsemblFungi.
DR   GO; GO:0006384; P:transcription initiation from RNA polymerase III promoter; IEA:EnsemblFungi.
DR   GO; GO:0042797; P:tRNA transcription by RNA polymerase III; IEA:EnsemblFungi.
DR   Gene3D; 3.40.1340.10; -; 1.
DR   Gene3D; 3.90.940.20; -; 1.
DR   HAMAP; MF_00025; RNApol_Rpo5_RPB5; 1.
DR   InterPro; IPR014381; Arch_Rpo5/euc_Rpb5.
DR   InterPro; IPR005571; RNA_pol_Rpb5_N.
DR   InterPro; IPR036710; RNA_pol_Rpb5_N_sf.
DR   InterPro; IPR000783; RNA_pol_subH/Rpb5_C.
DR   InterPro; IPR020608; RNA_pol_subH/Rpb5_CS.
DR   InterPro; IPR035913; RPB5-like_sf.
DR   PANTHER; PTHR10535; PTHR10535; 1.
DR   Pfam; PF01191; RNA_pol_Rpb5_C; 1.
DR   Pfam; PF03871; RNA_pol_Rpb5_N; 1.
DR   PIRSF; PIRSF000747; RPB5; 1.
DR   SUPFAM; SSF53036; SSF53036; 1.
DR   SUPFAM; SSF55287; SSF55287; 1.
DR   PROSITE; PS01110; RNA_POL_H_23KD; 1.
PE   3: Inferred from homology;
KW   DNA-directed RNA polymerase; Nucleus; Reference proteome; Transcription.
FT   CHAIN           1..215
FT                   /note="DNA-directed RNA polymerases I, II, and III subunit
FT                   RPABC1"
FT                   /id="PRO_0000146080"
SQ   SEQUENCE   215 AA;  25137 MW;  20BE9A97E1DB1AF8 CRC64;
     MDQENDRSIS RLWRTFRTVK EMVRDRGYFI AQEELDLTLE DFKVKYCDSM GRAQRKMMSF
     QANPTEESMT KFPDMGTLWV EFCDEPSVGV KTMKTFVIHI QEKQFQTGIF IYQNNITPSA
     MKLVPSIPPA TIETFHEAAL VVNITHHDLV PKHIRLNEEE KAELLKRYRL KESQLPRIQR
     ADPVALYLGL KRGEVVKIIR KSETAGRYAS YRICM