RPAC2_DANRE
ID RPAC2_DANRE Reviewed; 112 AA.
AC Q6DRI4; A4FUL5;
DT 18-APR-2006, integrated into UniProtKB/Swiss-Prot.
DT 16-AUG-2004, sequence version 1.
DT 03-AUG-2022, entry version 114.
DE RecName: Full=DNA-directed RNA polymerases I and III subunit RPAC2;
DE Short=RNA polymerases I and III subunit AC2;
DE AltName: Full=AC19;
DE AltName: Full=DNA-directed RNA polymerase I subunit D;
GN Name=polr1d; ORFNames=zgc:136449;
OS Danio rerio (Zebrafish) (Brachydanio rerio).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes;
OC Danionidae; Danioninae; Danio.
OX NCBI_TaxID=7955;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RX PubMed=15256591; DOI=10.1073/pnas.0403929101;
RA Amsterdam A., Nissen R.M., Sun Z., Swindell E.C., Farrington S.,
RA Hopkins N.;
RT "Identification of 315 genes essential for early zebrafish development.";
RL Proc. Natl. Acad. Sci. U.S.A. 101:12792-12797(2004).
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC TISSUE=Larval eye;
RG NIH - Zebrafish Gene Collection (ZGC) project;
RL Submitted (APR-2006) to the EMBL/GenBank/DDBJ databases.
CC -!- FUNCTION: DNA-dependent RNA polymerase catalyzes the transcription of
CC DNA into RNA using the four ribonucleoside triphosphates as substrates.
CC Common core component of RNA polymerases I and III which synthesize
CC ribosomal RNA precursors and small RNAs, such as 5S rRNA and tRNAs,
CC respectively (By similarity). {ECO:0000250}.
CC -!- SUBUNIT: Component of the RNA polymerase I (Pol I) and RNA polymerase
CC III (Pol III) complexes consisting of at least 13 and 17 subunits,
CC respectively. {ECO:0000250}.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000250}.
CC -!- SIMILARITY: Belongs to the archaeal Rpo11/eukaryotic RPB11/RPC19 RNA
CC polymerase subunit family. {ECO:0000305}.
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DR EMBL; AY648775; AAT68093.1; -; mRNA.
DR EMBL; BC115138; AAI15139.1; -; mRNA.
DR RefSeq; NP_001003888.1; NM_001003888.1.
DR AlphaFoldDB; Q6DRI4; -.
DR SMR; Q6DRI4; -.
DR STRING; 7955.ENSDARP00000054709; -.
DR PaxDb; Q6DRI4; -.
DR Ensembl; ENSDART00000054710; ENSDARP00000054709; ENSDARG00000037570.
DR GeneID; 445412; -.
DR KEGG; dre:445412; -.
DR CTD; 51082; -.
DR ZFIN; ZDB-GENE-040930-4; polr1d.
DR eggNOG; KOG3438; Eukaryota.
DR GeneTree; ENSGT00550000075160; -.
DR HOGENOM; CLU_090381_4_2_1; -.
DR InParanoid; Q6DRI4; -.
DR OMA; MRIQMYD; -.
DR OrthoDB; 1398114at2759; -.
DR PhylomeDB; Q6DRI4; -.
DR TreeFam; TF103035; -.
DR PRO; PR:Q6DRI4; -.
DR Proteomes; UP000000437; Genome assembly.
DR Proteomes; UP000814640; Chromosome 14.
DR Bgee; ENSDARG00000037570; Expressed in early embryo and 27 other tissues.
DR GO; GO:0005736; C:RNA polymerase I complex; IBA:GO_Central.
DR GO; GO:0005666; C:RNA polymerase III complex; IBA:GO_Central.
DR GO; GO:0003677; F:DNA binding; IEA:InterPro.
DR GO; GO:0003899; F:DNA-directed 5'-3' RNA polymerase activity; IEA:InterPro.
DR GO; GO:0046983; F:protein dimerization activity; IEA:InterPro.
DR GO; GO:0051216; P:cartilage development; IMP:ZFIN.
DR GO; GO:1904888; P:cranial skeletal system development; IMP:ZFIN.
DR GO; GO:0048703; P:embryonic viscerocranium morphogenesis; IMP:ZFIN.
DR GO; GO:0042254; P:ribosome biogenesis; IMP:ZFIN.
DR GO; GO:0006351; P:transcription, DNA-templated; IEA:InterPro.
DR CDD; cd07029; RNAP_I_III_AC19; 1.
DR Gene3D; 3.30.1360.10; -; 1.
DR HAMAP; MF_00261; RNApol_arch_Rpo11; 1.
DR InterPro; IPR036603; RBP11-like.
DR InterPro; IPR009025; RBP11-like_dimer.
DR InterPro; IPR008193; RNA_pol_Rpb11_13-16kDa_CS.
DR InterPro; IPR033898; RNAP_AC19.
DR Pfam; PF13656; RNA_pol_L_2; 1.
DR SUPFAM; SSF55257; SSF55257; 1.
DR PROSITE; PS01154; RNA_POL_L_13KD; 1.
PE 3: Inferred from homology;
KW DNA-directed RNA polymerase; Nucleus; Reference proteome; Transcription.
FT CHAIN 1..112
FT /note="DNA-directed RNA polymerases I and III subunit
FT RPAC2"
FT /id="PRO_0000232450"
SQ SEQUENCE 112 AA; 12755 MW; 1488CF59DFB38CFA CRC64;
MAELGQKHAL EMVRTDGADE GCVTFVLNEE DHTLGNSLRY MIMKSQDVEF CGYSITHPSE
SKINFRIQTR DGVPASEPLR NGLNNLTDVC KHVLQTFEAR MKEFKEQEES MT