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RPAC2_DANRE
ID   RPAC2_DANRE             Reviewed;         112 AA.
AC   Q6DRI4; A4FUL5;
DT   18-APR-2006, integrated into UniProtKB/Swiss-Prot.
DT   16-AUG-2004, sequence version 1.
DT   03-AUG-2022, entry version 114.
DE   RecName: Full=DNA-directed RNA polymerases I and III subunit RPAC2;
DE            Short=RNA polymerases I and III subunit AC2;
DE   AltName: Full=AC19;
DE   AltName: Full=DNA-directed RNA polymerase I subunit D;
GN   Name=polr1d; ORFNames=zgc:136449;
OS   Danio rerio (Zebrafish) (Brachydanio rerio).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes;
OC   Danionidae; Danioninae; Danio.
OX   NCBI_TaxID=7955;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RX   PubMed=15256591; DOI=10.1073/pnas.0403929101;
RA   Amsterdam A., Nissen R.M., Sun Z., Swindell E.C., Farrington S.,
RA   Hopkins N.;
RT   "Identification of 315 genes essential for early zebrafish development.";
RL   Proc. Natl. Acad. Sci. U.S.A. 101:12792-12797(2004).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   TISSUE=Larval eye;
RG   NIH - Zebrafish Gene Collection (ZGC) project;
RL   Submitted (APR-2006) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: DNA-dependent RNA polymerase catalyzes the transcription of
CC       DNA into RNA using the four ribonucleoside triphosphates as substrates.
CC       Common core component of RNA polymerases I and III which synthesize
CC       ribosomal RNA precursors and small RNAs, such as 5S rRNA and tRNAs,
CC       respectively (By similarity). {ECO:0000250}.
CC   -!- SUBUNIT: Component of the RNA polymerase I (Pol I) and RNA polymerase
CC       III (Pol III) complexes consisting of at least 13 and 17 subunits,
CC       respectively. {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the archaeal Rpo11/eukaryotic RPB11/RPC19 RNA
CC       polymerase subunit family. {ECO:0000305}.
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DR   EMBL; AY648775; AAT68093.1; -; mRNA.
DR   EMBL; BC115138; AAI15139.1; -; mRNA.
DR   RefSeq; NP_001003888.1; NM_001003888.1.
DR   AlphaFoldDB; Q6DRI4; -.
DR   SMR; Q6DRI4; -.
DR   STRING; 7955.ENSDARP00000054709; -.
DR   PaxDb; Q6DRI4; -.
DR   Ensembl; ENSDART00000054710; ENSDARP00000054709; ENSDARG00000037570.
DR   GeneID; 445412; -.
DR   KEGG; dre:445412; -.
DR   CTD; 51082; -.
DR   ZFIN; ZDB-GENE-040930-4; polr1d.
DR   eggNOG; KOG3438; Eukaryota.
DR   GeneTree; ENSGT00550000075160; -.
DR   HOGENOM; CLU_090381_4_2_1; -.
DR   InParanoid; Q6DRI4; -.
DR   OMA; MRIQMYD; -.
DR   OrthoDB; 1398114at2759; -.
DR   PhylomeDB; Q6DRI4; -.
DR   TreeFam; TF103035; -.
DR   PRO; PR:Q6DRI4; -.
DR   Proteomes; UP000000437; Genome assembly.
DR   Proteomes; UP000814640; Chromosome 14.
DR   Bgee; ENSDARG00000037570; Expressed in early embryo and 27 other tissues.
DR   GO; GO:0005736; C:RNA polymerase I complex; IBA:GO_Central.
DR   GO; GO:0005666; C:RNA polymerase III complex; IBA:GO_Central.
DR   GO; GO:0003677; F:DNA binding; IEA:InterPro.
DR   GO; GO:0003899; F:DNA-directed 5'-3' RNA polymerase activity; IEA:InterPro.
DR   GO; GO:0046983; F:protein dimerization activity; IEA:InterPro.
DR   GO; GO:0051216; P:cartilage development; IMP:ZFIN.
DR   GO; GO:1904888; P:cranial skeletal system development; IMP:ZFIN.
DR   GO; GO:0048703; P:embryonic viscerocranium morphogenesis; IMP:ZFIN.
DR   GO; GO:0042254; P:ribosome biogenesis; IMP:ZFIN.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:InterPro.
DR   CDD; cd07029; RNAP_I_III_AC19; 1.
DR   Gene3D; 3.30.1360.10; -; 1.
DR   HAMAP; MF_00261; RNApol_arch_Rpo11; 1.
DR   InterPro; IPR036603; RBP11-like.
DR   InterPro; IPR009025; RBP11-like_dimer.
DR   InterPro; IPR008193; RNA_pol_Rpb11_13-16kDa_CS.
DR   InterPro; IPR033898; RNAP_AC19.
DR   Pfam; PF13656; RNA_pol_L_2; 1.
DR   SUPFAM; SSF55257; SSF55257; 1.
DR   PROSITE; PS01154; RNA_POL_L_13KD; 1.
PE   3: Inferred from homology;
KW   DNA-directed RNA polymerase; Nucleus; Reference proteome; Transcription.
FT   CHAIN           1..112
FT                   /note="DNA-directed RNA polymerases I and III subunit
FT                   RPAC2"
FT                   /id="PRO_0000232450"
SQ   SEQUENCE   112 AA;  12755 MW;  1488CF59DFB38CFA CRC64;
     MAELGQKHAL EMVRTDGADE GCVTFVLNEE DHTLGNSLRY MIMKSQDVEF CGYSITHPSE
     SKINFRIQTR DGVPASEPLR NGLNNLTDVC KHVLQTFEAR MKEFKEQEES MT
 
 
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