ID   RPB11_BOVIN             Reviewed;         117 AA.
AC   Q32P79;
DT   17-OCT-2006, integrated into UniProtKB/Swiss-Prot.
DT   06-DEC-2005, sequence version 1.
DT   03-AUG-2022, entry version 110.
DE   RecName: Full=DNA-directed RNA polymerase II subunit RPB11;
DE            Short=RNA polymerase II subunit B11;
DE   AltName: Full=DNA-directed RNA polymerase II subunit J;
GN   Name=POLR2J;
OS   Bos taurus (Bovine).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae;
OC   Bovinae; Bos.
OX   NCBI_TaxID=9913;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   STRAIN=Crossbred X Angus; TISSUE=Liver;
RG   NIH - Mammalian Gene Collection (MGC) project;
RL   Submitted (OCT-2005) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: DNA-dependent RNA polymerase catalyzes the transcription of
CC       DNA into RNA using the four ribonucleoside triphosphates as substrates.
CC       Component of RNA polymerase II which synthesizes mRNA precursors and
CC       many functional non-coding RNAs. Pol II is the central component of the
CC       basal RNA polymerase II transcription machinery. It is composed of
CC       mobile elements that move relative to each other. RPB11 is part of the
CC       core element with the central large cleft (By similarity).
CC       {ECO:0000250}.
CC   -!- SUBUNIT: Component of the RNA polymerase II (Pol II) complex consisting
CC       of 12 subunits. Interacts with AATF (By similarity). {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the archaeal Rpo11/eukaryotic RPB11/RPC19 RNA
CC       polymerase subunit family. {ECO:0000305}.
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DR   EMBL; BC108226; AAI08227.1; -; mRNA.
DR   RefSeq; NP_001032560.1; NM_001037483.2.
DR   PDB; 5FLM; EM; 3.40 A; K=1-117.
DR   PDB; 5OIK; EM; 3.70 A; K=1-117.
DR   PDBsum; 5FLM; -.
DR   PDBsum; 5OIK; -.
DR   AlphaFoldDB; Q32P79; -.
DR   SMR; Q32P79; -.
DR   DIP; DIP-61196N; -.
DR   IntAct; Q32P79; 2.
DR   STRING; 9913.ENSBTAP00000007165; -.
DR   PaxDb; Q32P79; -.
DR   PRIDE; Q32P79; -.
DR   Ensembl; ENSBTAT00000007165; ENSBTAP00000007165; ENSBTAG00000005446.
DR   GeneID; 540428; -.
DR   KEGG; bta:540428; -.
DR   CTD; 5439; -.
DR   VEuPathDB; HostDB:ENSBTAG00000005446; -.
DR   eggNOG; KOG4392; Eukaryota.
DR   GeneTree; ENSGT00940000164393; -.
DR   HOGENOM; CLU_090381_2_2_1; -.
DR   InParanoid; Q32P79; -.
DR   OMA; LEQACTK; -.
DR   OrthoDB; 1398114at2759; -.
DR   TreeFam; TF103044; -.
DR   Reactome; R-BTA-113418; Formation of the Early Elongation Complex.
DR   Reactome; R-BTA-674695; RNA Polymerase II Pre-transcription Events.
DR   Proteomes; UP000009136; Chromosome 25.
DR   Bgee; ENSBTAG00000005446; Expressed in oocyte and 105 other tissues.
DR   ExpressionAtlas; Q32P79; baseline and differential.
DR   GO; GO:0005634; C:nucleus; ISS:UniProtKB.
DR   GO; GO:0005665; C:RNA polymerase II, core complex; ISS:UniProtKB.
DR   GO; GO:0003677; F:DNA binding; IEA:InterPro.
DR   GO; GO:0046983; F:protein dimerization activity; IEA:InterPro.
DR   GO; GO:0001055; F:RNA polymerase II activity; IEA:InterPro.
DR   GO; GO:0006366; P:transcription by RNA polymerase II; ISS:UniProtKB.
DR   CDD; cd06926; RNAP_II_RPB11; 1.
DR   Gene3D; 3.30.1360.10; -; 1.
DR   HAMAP; MF_00261; RNApol_arch_Rpo11; 1.
DR   InterPro; IPR037685; RBP11.
DR   InterPro; IPR036603; RBP11-like.
DR   InterPro; IPR009025; RBP11-like_dimer.
DR   InterPro; IPR008193; RNA_pol_Rpb11_13-16kDa_CS.
DR   Pfam; PF13656; RNA_pol_L_2; 1.
DR   SUPFAM; SSF55257; SSF55257; 1.
DR   PROSITE; PS01154; RNA_POL_L_13KD; 1.
PE   1: Evidence at protein level;
KW   3D-structure; Acetylation; DNA-directed RNA polymerase; Nucleus;
KW   Reference proteome; Transcription.
FT   CHAIN           1..117
FT                   /note="DNA-directed RNA polymerase II subunit RPB11"
FT                   /id="PRO_0000253448"
FT   MOD_RES         1
FT                   /note="N-acetylmethionine"
FT                   /evidence="ECO:0000250|UniProtKB:P52435"
FT   STRAND          8..10
FT                   /evidence="ECO:0007829|PDB:5FLM"
FT   STRAND          18..23
FT                   /evidence="ECO:0007829|PDB:5FLM"
FT   STRAND          30..36
FT                   /evidence="ECO:0007829|PDB:5FLM"
FT   HELIX           40..50
FT                   /evidence="ECO:0007829|PDB:5FLM"
FT   STRAND          56..62
FT                   /evidence="ECO:0007829|PDB:5FLM"
FT   STRAND          70..77
FT                   /evidence="ECO:0007829|PDB:5FLM"
FT   HELIX           83..112
FT                   /evidence="ECO:0007829|PDB:5FLM"
SQ   SEQUENCE   117 AA;  13293 MW;  6F78AB256EF8F647 CRC64;
     MNAPPAFESF LLFEGEKKIT INKDTKVPNA CLFTINKEDH TLGNIIKSQL LKDPQVLFAG
     YKVPHPLEHK IIIRVQTTPD YSPQEAFTNA ITDLISELSL LEERFRVAIK DKQEGIE