ID   RPB11_SCHPO             Reviewed;         123 AA.
AC   P87123;
DT   15-JUL-1998, integrated into UniProtKB/Swiss-Prot.
DT   01-JUL-1997, sequence version 1.
DT   25-MAY-2022, entry version 148.
DE   RecName: Full=DNA-directed RNA polymerase II subunit RPB11;
DE            Short=RNA polymerase II subunit B11;
DE   AltName: Full=DNA-directed RNA polymerase II 14.1 kDa polypeptide;
GN   Name=rpb11; ORFNames=SPAC3A12.07;
OS   Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Taphrinomycotina;
OC   Schizosaccharomycetes; Schizosaccharomycetales; Schizosaccharomycetaceae;
OC   Schizosaccharomyces.
OX   NCBI_TaxID=284812;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA / MRNA].
RC   STRAIN=972 / ATCC 24843, and JY741;
RX   PubMed=9322754; DOI=10.1016/s0378-1119(97)00222-9;
RA   Sakurai H., Ishihama A.;
RT   "Gene organization and protein sequence of the small subunits of
RT   Schizosaccharomyces pombe RNA polymerase II.";
RL   Gene 196:165-174(1997).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [MRNA].
RC   STRAIN=972 / ATCC 24843;
RX   PubMed=9499374;
RA   Shpakovski G.V., Lebedenko E.N.;
RT   "Molecular cloning of rpb5+, rpb7+ and rpb11+ genes of the fission yeast
RT   Schizosaccharomyces pombe: completing primary structure of all
RT   indispensable subunits of its RNA polymerase II.";
RL   Bioorg. Khim. 23:988-991(1997).
RN   [3]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=972 / ATCC 24843;
RX   PubMed=11859360; DOI=10.1038/nature724;
RA   Wood V., Gwilliam R., Rajandream M.A., Lyne M.H., Lyne R., Stewart A.,
RA   Sgouros J.G., Peat N., Hayles J., Baker S.G., Basham D., Bowman S.,
RA   Brooks K., Brown D., Brown S., Chillingworth T., Churcher C.M., Collins M.,
RA   Connor R., Cronin A., Davis P., Feltwell T., Fraser A., Gentles S.,
RA   Goble A., Hamlin N., Harris D.E., Hidalgo J., Hodgson G., Holroyd S.,
RA   Hornsby T., Howarth S., Huckle E.J., Hunt S., Jagels K., James K.D.,
RA   Jones L., Jones M., Leather S., McDonald S., McLean J., Mooney P.,
RA   Moule S., Mungall K.L., Murphy L.D., Niblett D., Odell C., Oliver K.,
RA   O'Neil S., Pearson D., Quail M.A., Rabbinowitsch E., Rutherford K.M.,
RA   Rutter S., Saunders D., Seeger K., Sharp S., Skelton J., Simmonds M.N.,
RA   Squares R., Squares S., Stevens K., Taylor K., Taylor R.G., Tivey A.,
RA   Walsh S.V., Warren T., Whitehead S., Woodward J.R., Volckaert G., Aert R.,
RA   Robben J., Grymonprez B., Weltjens I., Vanstreels E., Rieger M.,
RA   Schaefer M., Mueller-Auer S., Gabel C., Fuchs M., Duesterhoeft A.,
RA   Fritzc C., Holzer E., Moestl D., Hilbert H., Borzym K., Langer I., Beck A.,
RA   Lehrach H., Reinhardt R., Pohl T.M., Eger P., Zimmermann W., Wedler H.,
RA   Wambutt R., Purnelle B., Goffeau A., Cadieu E., Dreano S., Gloux S.,
RA   Lelaure V., Mottier S., Galibert F., Aves S.J., Xiang Z., Hunt C.,
RA   Moore K., Hurst S.M., Lucas M., Rochet M., Gaillardin C., Tallada V.A.,
RA   Garzon A., Thode G., Daga R.R., Cruzado L., Jimenez J., Sanchez M.,
RA   del Rey F., Benito J., Dominguez A., Revuelta J.L., Moreno S.,
RA   Armstrong J., Forsburg S.L., Cerutti L., Lowe T., McCombie W.R.,
RA   Paulsen I., Potashkin J., Shpakovski G.V., Ussery D., Barrell B.G.,
RA   Nurse P.;
RT   "The genome sequence of Schizosaccharomyces pombe.";
RL   Nature 415:871-880(2002).
CC   -!- FUNCTION: DNA-dependent RNA polymerase catalyzes the transcription of
CC       DNA into RNA using the four ribonucleoside triphosphates as substrates.
CC       Component of RNA polymerase II which synthesizes mRNA precursors and
CC       many functional non-coding RNAs. Pol II is the central component of the
CC       basal RNA polymerase II transcription machinery. It is composed of
CC       mobile elements that move relative to each other. RPB11 is part of the
CC       core element with the central large cleft (By similarity).
CC       {ECO:0000250}.
CC   -!- SUBUNIT: Component of the RNA polymerase II (Pol II) complex consisting
CC       of 12 subunits. {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the archaeal Rpo11/eukaryotic RPB11/RPC19 RNA
CC       polymerase subunit family. {ECO:0000305}.
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DR   EMBL; D89597; BAA22806.1; -; Genomic_DNA.
DR   EMBL; D85902; BAA22801.1; -; mRNA.
DR   EMBL; AF027822; AAB92517.1; -; mRNA.
DR   EMBL; CU329670; CAB08752.1; -; Genomic_DNA.
DR   PIR; T38675; T38675.
DR   RefSeq; NP_593333.1; NM_001018765.2.
DR   PDB; 3H0G; X-ray; 3.65 A; K/W=1-123.
DR   PDB; 5U0S; EM; 7.80 A; k=1-123.
DR   PDBsum; 3H0G; -.
DR   PDBsum; 5U0S; -.
DR   AlphaFoldDB; P87123; -.
DR   SMR; P87123; -.
DR   BioGRID; 279544; 11.
DR   IntAct; P87123; 2.
DR   STRING; 4896.SPAC3A12.07.1; -.
DR   iPTMnet; P87123; -.
DR   MaxQB; P87123; -.
DR   PaxDb; P87123; -.
DR   EnsemblFungi; SPAC3A12.07.1; SPAC3A12.07.1:pep; SPAC3A12.07.
DR   GeneID; 2543112; -.
DR   KEGG; spo:SPAC3A12.07; -.
DR   PomBase; SPAC3A12.07; rpb11.
DR   VEuPathDB; FungiDB:SPAC3A12.07; -.
DR   eggNOG; KOG4392; Eukaryota.
DR   HOGENOM; CLU_090381_2_1_1; -.
DR   InParanoid; P87123; -.
DR   OMA; NQPERYE; -.
DR   PhylomeDB; P87123; -.
DR   Reactome; R-SPO-113418; Formation of the Early Elongation Complex.
DR   Reactome; R-SPO-5578749; Transcriptional regulation by small RNAs.
DR   Reactome; R-SPO-674695; RNA Polymerase II Pre-transcription Events.
DR   Reactome; R-SPO-6781823; Formation of TC-NER Pre-Incision Complex.
DR   Reactome; R-SPO-6782135; Dual incision in TC-NER.
DR   Reactome; R-SPO-6782210; Gap-filling DNA repair synthesis and ligation in TC-NER.
DR   Reactome; R-SPO-6796648; TP53 Regulates Transcription of DNA Repair Genes.
DR   Reactome; R-SPO-6807505; RNA polymerase II transcribes snRNA genes.
DR   Reactome; R-SPO-72086; mRNA Capping.
DR   Reactome; R-SPO-72165; mRNA Splicing - Minor Pathway.
DR   Reactome; R-SPO-73776; RNA Polymerase II Promoter Escape.
DR   Reactome; R-SPO-73779; RNA Polymerase II Transcription Pre-Initiation And Promoter Opening.
DR   Reactome; R-SPO-75953; RNA Polymerase II Transcription Initiation.
DR   Reactome; R-SPO-75955; RNA Polymerase II Transcription Elongation.
DR   Reactome; R-SPO-76042; RNA Polymerase II Transcription Initiation And Promoter Clearance.
DR   Reactome; R-SPO-77075; RNA Pol II CTD phosphorylation and interaction with CE.
DR   Reactome; R-SPO-9018519; Estrogen-dependent gene expression.
DR   EvolutionaryTrace; P87123; -.
DR   PRO; PR:P87123; -.
DR   Proteomes; UP000002485; Chromosome I.
DR   GO; GO:0005829; C:cytosol; HDA:PomBase.
DR   GO; GO:0005634; C:nucleus; HDA:PomBase.
DR   GO; GO:0005665; C:RNA polymerase II, core complex; IDA:PomBase.
DR   GO; GO:0003677; F:DNA binding; IEA:InterPro.
DR   GO; GO:0046983; F:protein dimerization activity; IEA:InterPro.
DR   GO; GO:0001055; F:RNA polymerase II activity; IEA:InterPro.
DR   GO; GO:0006366; P:transcription by RNA polymerase II; EXP:PomBase.
DR   CDD; cd06926; RNAP_II_RPB11; 1.
DR   Gene3D; 3.30.1360.10; -; 1.
DR   HAMAP; MF_00261; RNApol_arch_Rpo11; 1.
DR   InterPro; IPR037685; RBP11.
DR   InterPro; IPR036603; RBP11-like.
DR   InterPro; IPR009025; RBP11-like_dimer.
DR   InterPro; IPR008193; RNA_pol_Rpb11_13-16kDa_CS.
DR   Pfam; PF13656; RNA_pol_L_2; 1.
DR   SUPFAM; SSF55257; SSF55257; 1.
DR   PROSITE; PS01154; RNA_POL_L_13KD; 1.
PE   1: Evidence at protein level;
KW   3D-structure; DNA-directed RNA polymerase; Nucleus; Reference proteome;
KW   Transcription.
FT   CHAIN           1..123
FT                   /note="DNA-directed RNA polymerase II subunit RPB11"
FT                   /id="PRO_0000149314"
SQ   SEQUENCE   123 AA;  14127 MW;  73FAFDF2F468386E CRC64;
     MNQPERYELI ELMGLPKVTY ELDSKSPNAA VVTLEKEDHT LANMLANQLL SDERVLFAGY
     KVPHPLNHNF ILRVQTVEDC SPKQVIVDAA KSLITHLEEI KVNFMREWEL KMISVEGVEM
     EFS