ID   RPB3_ASFM2              Reviewed;         359 AA.
AC   Q65229;
DT   05-MAY-2009, integrated into UniProtKB/Swiss-Prot.
DT   05-MAY-2009, sequence version 2.
DT   03-AUG-2022, entry version 82.
DE   RecName: Full=DNA-directed RNA polymerase RPB3-11 homolog {ECO:0000250|UniProtKB:Q65184};
DE            Short=RPB3-11 homolog {ECO:0000305};
GN   OrderedLocusNames=Mal-121; ORFNames=j1L;
OS   African swine fever virus (isolate Tick/Malawi/Lil 20-1/1983) (ASFV).
OC   Viruses; Varidnaviria; Bamfordvirae; Nucleocytoviricota; Pokkesviricetes;
OC   Asfuvirales; Asfarviridae; Asfivirus.
OX   NCBI_TaxID=10500;
OH   NCBI_TaxID=6937; Ornithodoros (relapsing fever ticks).
OH   NCBI_TaxID=85517; Phacochoerus aethiopicus (Warthog).
OH   NCBI_TaxID=41426; Phacochoerus africanus (Warthog).
OH   NCBI_TaxID=273792; Potamochoerus larvatus (Bushpig).
OH   NCBI_TaxID=9823; Sus scrofa (Pig).
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RX   PubMed=8021596; DOI=10.1099/0022-1317-75-7-1655;
RA   Dixon L.K., Twigg S.R.F., Baylis S.A., Vydelingum S., Bristow C.,
RA   Hammond J.M., Smith G.L.;
RT   "Nucleotide sequence of a 55 kbp region from the right end of the genome of
RT   a pathogenic African swine fever virus isolate (Malawi LIL20/1).";
RL   J. Gen. Virol. 75:1655-1684(1994).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA   Kutish G.F., Rock D.L.;
RT   "African swine fever virus genomes.";
RL   Submitted (MAR-2003) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Component of the DNA-directed RNA polymerase (RNAP) that
CC       catalyzes the transcription in the cytoplasm of viral DNA into RNA
CC       using the four ribonucleoside triphosphates as substrates.
CC       {ECO:0000250|UniProtKB:P19387}.
CC   -!- SUBUNIT: Part of the viral DNA-directed RNA polymerase that consists of
CC       8 polII-like subunits (RPB1, RPB2, RPB3, RPB5, RPB6, RPB7, RPB9,
CC       RPB10), a capping enzyme and a termination factor.
CC       {ECO:0000250|UniProtKB:Q65184}.
CC   -!- SUBCELLULAR LOCATION: Host cytoplasm {ECO:0000305}. Virion
CC       {ECO:0000250|UniProtKB:Q65184}. Note=Found in association with viral
CC       nucleoid. {ECO:0000250|UniProtKB:Q65184}.
CC   -!- INDUCTION: Expressed in the early phase of the viral replicative cycle.
CC       {ECO:0000305}.
CC   -!- SIMILARITY: In the N-terminal section; belongs to the archaeal
CC       RpoD/eukaryotic RPB3 RNA polymerase subunit family. {ECO:0000305}.
CC   -!- SIMILARITY: In the C-terminal section; belongs to the archaeal
CC       RpoL/eukaryotic RPB11/RPC19 RNA polymerase subunit family.
CC       {ECO:0000305}.
CC   -!- SEQUENCE CAUTION:
CC       Sequence=CAA50821.1; Type=Erroneous initiation; Note=Truncated N-terminus.; Evidence={ECO:0000305};
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DR   EMBL; X71982; CAA50821.1; ALT_INIT; Genomic_DNA.
DR   EMBL; AY261361; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   SMR; Q65229; -.
DR   Proteomes; UP000000860; Genome.
DR   GO; GO:0000428; C:DNA-directed RNA polymerase complex; IEA:UniProtKB-KW.
DR   GO; GO:0030430; C:host cell cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0046983; F:protein dimerization activity; IEA:InterPro.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:InterPro.
DR   GO; GO:0019083; P:viral transcription; IEA:UniProtKB-KW.
DR   Gene3D; 3.30.1360.10; -; 1.
DR   InterPro; IPR036603; RBP11-like.
DR   InterPro; IPR009025; RBP11-like_dimer.
DR   InterPro; IPR036643; RNApol_insert_sf.
DR   Pfam; PF13656; RNA_pol_L_2; 1.
DR   SUPFAM; SSF55257; SSF55257; 1.
DR   SUPFAM; SSF56553; SSF56553; 1.
PE   3: Inferred from homology;
KW   DNA-directed RNA polymerase; Early protein; Host cytoplasm; Transcription;
KW   Viral transcription; Virion.
FT   CHAIN           1..359
FT                   /note="DNA-directed RNA polymerase RPB3-11 homolog"
FT                   /id="PRO_0000373165"
SQ   SEQUENCE   359 AA;  41339 MW;  CC14EA8A4552EC51 CRC64;
     MEKIFQNVEI KPLLIDFSNP FIKNAAKKLF QLEEQLPLVP VNVVMDFKGI NRAAVHGLSR
     VLQDEIPNYM LDIKPGGYKI EDSTDLFMTE QFIRNRINFI PIYAENESLV FALRSLNNSC
     EVKTIYTRDL IQVAGPKLKY PIFNPTFEIG FLQPGKSLII EDIYIKKGIG RKHAAFNLAV
     KTHFSHLDIE QYPTDKKEYM ALSGYKQSSM TSDPRHHRLG LCFPAVPMPR INKAVRTYLK
     NACRVIIGRI QSIQKIYENF EEPQPELVLF SMDEEKTKAI ITIKDETHTI GNLLKTCIYE
     MIPDISFVGY QCVPHKQEMV LTIIHKASQE DLITLLEKSI QNIIQMFQTL EKNIDELIA