ID   RPB6_ASFM2              Reviewed;         151 AA.
AC   P0C9D6; Q08399;
DT   05-MAY-2009, integrated into UniProtKB/Swiss-Prot.
DT   05-MAY-2009, sequence version 1.
DT   03-AUG-2022, entry version 45.
DE   RecName: Full=DNA-directed RNA polymerase RPB6 homolog {ECO:0000250|UniProtKB:P42484};
DE            Short=RPB6 homolog {ECO:0000250|UniProtKB:P42484};
GN   OrderedLocusNames=Mal-077; ORFNames=g6L;
OS   African swine fever virus (isolate Tick/Malawi/Lil 20-1/1983) (ASFV).
OC   Viruses; Varidnaviria; Bamfordvirae; Nucleocytoviricota; Pokkesviricetes;
OC   Asfuvirales; Asfarviridae; Asfivirus.
OX   NCBI_TaxID=10500;
OH   NCBI_TaxID=6937; Ornithodoros (relapsing fever ticks).
OH   NCBI_TaxID=85517; Phacochoerus aethiopicus (Warthog).
OH   NCBI_TaxID=41426; Phacochoerus africanus (Warthog).
OH   NCBI_TaxID=273792; Potamochoerus larvatus (Bushpig).
OH   NCBI_TaxID=9823; Sus scrofa (Pig).
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA   Kutish G.F., Rock D.L.;
RT   "African swine fever virus genomes.";
RL   Submitted (MAR-2003) to the EMBL/GenBank/DDBJ databases.
RN   [2]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA] OF 1-140.
RX   PubMed=8332503; DOI=10.1093/nar/21.12.2940;
RA   Lu Z., Kutish G.F., Sussman M.D., Rock D.L.;
RT   "An African swine fever virus gene with a similarity to eukaryotic RNA
RT   polymerase subunit 6.";
RL   Nucleic Acids Res. 21:2940-2940(1993).
CC   -!- FUNCTION: Component of the DNA-directed RNA polymerase (RNAP) that
CC       catalyzes the transcription in the cytoplasm of viral DNA into RNA
CC       using the four ribonucleoside triphosphates as substrates.
CC       {ECO:0000250|UniProtKB:P42484}.
CC   -!- SUBUNIT: Part of the viral DNA-directed RNA polymerase that consists of
CC       8 polII-like subunits (RPB1, RPB2, RPB3, RPB5, RPB6, RPB7, RPB9,
CC       RPB10), a capping enzyme and a termination factor.
CC       {ECO:0000250|UniProtKB:P42484}.
CC   -!- SUBCELLULAR LOCATION: Host cytoplasm {ECO:0000305}. Virion
CC       {ECO:0000250|UniProtKB:P42484}. Note=Found in association with viral
CC       nucleoid. {ECO:0000250|UniProtKB:P42484}.
CC   -!- SIMILARITY: Belongs to the archaeal RpoK/eukaryotic RPB6 RNA polymerase
CC       subunit family. {ECO:0000305}.
CC   -!- SEQUENCE CAUTION:
CC       Sequence=AAA42731.1; Type=Erroneous termination; Note=Truncated C-terminus.; Evidence={ECO:0000305};
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; AY261361; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; L15411; AAA42731.1; ALT_TERM; Genomic_DNA.
DR   SMR; P0C9D6; -.
DR   Proteomes; UP000000860; Genome.
DR   GO; GO:0000428; C:DNA-directed RNA polymerase complex; IEA:UniProtKB-KW.
DR   GO; GO:0030430; C:host cell cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0003677; F:DNA binding; IEA:InterPro.
DR   GO; GO:0003899; F:DNA-directed 5'-3' RNA polymerase activity; IEA:InterPro.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:InterPro.
DR   Gene3D; 3.90.940.10; -; 1.
DR   InterPro; IPR020708; DNA-dir_RNA_polK_14-18kDa_CS.
DR   InterPro; IPR006110; Pol_omega/Rpo6/RPB6.
DR   InterPro; IPR036161; RPB6/omega-like_sf.
DR   InterPro; IPR006111; Rpo6/Rpb6.
DR   Pfam; PF01192; RNA_pol_Rpb6; 1.
DR   PIRSF; PIRSF000778; RpoK/RPB6; 1.
DR   SMART; SM01409; RNA_pol_Rpb6; 1.
DR   SUPFAM; SSF63562; SSF63562; 1.
DR   PROSITE; PS01111; RNA_POL_K_14KD; 1.
PE   3: Inferred from homology;
KW   DNA-directed RNA polymerase; Host cytoplasm; Transcription; Virion.
FT   CHAIN           1..151
FT                   /note="DNA-directed RNA polymerase RPB6 homolog"
FT                   /id="PRO_0000373152"
FT   REGION          20..46
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        20..39
FT                   /note="Acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   VARIANT         140..151
FT                   /note="Missing"
FT                   /evidence="ECO:0000269|PubMed:8332503"
SQ   SEQUENCE   151 AA;  17136 MW;  DCC1CCD88ABECABB CRC64;
     MADNDNEDVI MDDLVEEYVE TEEENFVDSE EESEDKSEDK DEIVESPSIC EGFVQASSQT
     LVIIPDNERI TSNVLTTFEA TRLVAVRAQQ LAINGSTMLK KKYSSPIDIA KQELFNRKIP
     LLVMRCIKVT PEGQKIVEIW NPREMGIPLL D