ID   RPB7_ASFK5              Reviewed;         335 AA.
AC   P0CAE7;
DT   05-MAY-2009, integrated into UniProtKB/Swiss-Prot.
DT   05-MAY-2009, sequence version 1.
DT   03-AUG-2022, entry version 28.
DE   RecName: Full=DNA-directed RNA polymerase RPB7 homolog {ECO:0000250|UniProtKB:Q89907};
DE            Short=RPB7 homolog {ECO:0000305};
GN   OrderedLocusNames=Ken-117;
OS   African swine fever virus (isolate Pig/Kenya/KEN-50/1950) (ASFV).
OC   Viruses; Varidnaviria; Bamfordvirae; Nucleocytoviricota; Pokkesviricetes;
OC   Asfuvirales; Asfarviridae; Asfivirus.
OX   NCBI_TaxID=561445;
OH   NCBI_TaxID=6937; Ornithodoros (relapsing fever ticks).
OH   NCBI_TaxID=85517; Phacochoerus aethiopicus (Warthog).
OH   NCBI_TaxID=41426; Phacochoerus africanus (Warthog).
OH   NCBI_TaxID=273792; Potamochoerus larvatus (Bushpig).
OH   NCBI_TaxID=9823; Sus scrofa (Pig).
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA   Kutish G.F., Rock D.L.;
RT   "African swine fever virus genomes.";
RL   Submitted (MAR-2003) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Component of the DNA-directed RNA polymerase (RNAP) that
CC       catalyzes the transcription in the cytoplasm of viral DNA into RNA
CC       using the four ribonucleoside triphosphates as substrates.
CC       {ECO:0000250|UniProtKB:P62487}.
CC   -!- SUBUNIT: Part of the viral DNA-directed RNA polymerase that consists of
CC       8 polII-like subunits (RPB1, RPB2, RPB3, RPB5, RPB6, RPB7, RPB9,
CC       RPB10), a capping enzyme and a termination factor.
CC       {ECO:0000250|UniProtKB:Q89907}.
CC   -!- SUBCELLULAR LOCATION: Host cytoplasm {ECO:0000305}. Virion. Note=Found
CC       in association with viral nucleoid. {ECO:0000250|UniProtKB:Q89907}.
CC   -!- INDUCTION: Expressed in the early phase of the viral replicative cycle.
CC       {ECO:0000250|UniProtKB:Q89907}.
CC   -!- DOMAIN: Contains an extended C-terminus, with no homology to
CC       characterized proteins. {ECO:0000250|UniProtKB:Q89907}.
CC   -!- SIMILARITY: Belongs to the Asfivirus DNA-directed RNA polymerase RPB7
CC       homolog family. {ECO:0000305}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; AY261360; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   Proteomes; UP000000861; Genome.
DR   GO; GO:0000428; C:DNA-directed RNA polymerase complex; IEA:UniProtKB-KW.
DR   GO; GO:0030430; C:host cell cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0019083; P:viral transcription; IEA:UniProtKB-KW.
PE   3: Inferred from homology;
KW   DNA-directed RNA polymerase; Host cytoplasm; Transcription;
KW   Viral transcription; Virion.
FT   CHAIN           1..335
FT                   /note="DNA-directed RNA polymerase RPB7 homolog"
FT                   /id="PRO_0000373654"
SQ   SEQUENCE   335 AA;  38270 MW;  81E034182F2569DD CRC64;
     MIDQKIFEIT LNIDDPANFC TNVEAHLLKE LENIYVGKCF KNSFIISITG VIQRSPCFIM
     RTNNSGRGYM HVRFSALVSY LNAFDLIAAV KIIKNDNNII LGESLLTEPV TIVIPSSESQ
     NNVAEVGQIV PVQLANSSVY YIPGRQQASA TGSIFIPKHT FSVYHVQEEL TQEQALNLTK
     LVNVIETLLD SRSKKDFKHI CFFEKLYYTY PISSDEILDL KIWKGPKGKE VSRLKPCNVL
     SFLYDALKNK SSSLGFWARP PDLFKSSPLA YQQDNNSFNT TELPIICSAE VMFVTLLKEI
     INYLQFMNDL CDTFNNEQLI KRHENIWMLI EQRKI