ID   RPB7_ASFM2              Reviewed;         335 AA.
AC   Q65221;
DT   05-MAY-2009, integrated into UniProtKB/Swiss-Prot.
DT   01-NOV-1996, sequence version 1.
DT   03-AUG-2022, entry version 61.
DE   RecName: Full=DNA-directed RNA polymerase RPB7 homolog {ECO:0000250|UniProtKB:Q89907};
DE            Short=RPB7 homolog {ECO:0000305};
GN   OrderedLocusNames=Mal-113; ORFNames=g9L;
OS   African swine fever virus (isolate Tick/Malawi/Lil 20-1/1983) (ASFV).
OC   Viruses; Varidnaviria; Bamfordvirae; Nucleocytoviricota; Pokkesviricetes;
OC   Asfuvirales; Asfarviridae; Asfivirus.
OX   NCBI_TaxID=10500;
OH   NCBI_TaxID=6937; Ornithodoros (relapsing fever ticks).
OH   NCBI_TaxID=85517; Phacochoerus aethiopicus (Warthog).
OH   NCBI_TaxID=41426; Phacochoerus africanus (Warthog).
OH   NCBI_TaxID=273792; Potamochoerus larvatus (Bushpig).
OH   NCBI_TaxID=9823; Sus scrofa (Pig).
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RX   PubMed=8021596; DOI=10.1099/0022-1317-75-7-1655;
RA   Dixon L.K., Twigg S.R.F., Baylis S.A., Vydelingum S., Bristow C.,
RA   Hammond J.M., Smith G.L.;
RT   "Nucleotide sequence of a 55 kbp region from the right end of the genome of
RT   a pathogenic African swine fever virus isolate (Malawi LIL20/1).";
RL   J. Gen. Virol. 75:1655-1684(1994).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA   Kutish G.F., Rock D.L.;
RT   "African swine fever virus genomes.";
RL   Submitted (MAR-2003) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Component of the DNA-directed RNA polymerase (RNAP) that
CC       catalyzes the transcription in the cytoplasm of viral DNA into RNA
CC       using the four ribonucleoside triphosphates as substrates.
CC       {ECO:0000250|UniProtKB:P62487}.
CC   -!- SUBUNIT: Part of the viral DNA-directed RNA polymerase that consists of
CC       8 polII-like subunits (RPB1, RPB2, RPB3, RPB5, RPB6, RPB7, RPB9,
CC       RPB10), a capping enzyme and a termination factor.
CC       {ECO:0000250|UniProtKB:Q89907}.
CC   -!- SUBCELLULAR LOCATION: Host cytoplasm {ECO:0000305}. Virion
CC       {ECO:0000250|UniProtKB:Q89907}. Note=Found in association with viral
CC       nucleoid. {ECO:0000250|UniProtKB:Q89907}.
CC   -!- INDUCTION: Expressed in the early phase of the viral replicative cycle.
CC       {ECO:0000250|UniProtKB:Q89907}.
CC   -!- DOMAIN: Contains an extended C-terminus, with no homology to
CC       characterized proteins. {ECO:0000250|UniProtKB:Q89907}.
CC   -!- SIMILARITY: Belongs to the Asfivirus DNA-directed RNA polymerase RPB7
CC       homolog family. {ECO:0000305}.
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DR   EMBL; X71982; CAA50811.1; -; Genomic_DNA.
DR   EMBL; AY261361; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   Proteomes; UP000000860; Genome.
DR   GO; GO:0000428; C:DNA-directed RNA polymerase complex; IEA:UniProtKB-KW.
DR   GO; GO:0030430; C:host cell cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0019083; P:viral transcription; IEA:UniProtKB-KW.
PE   3: Inferred from homology;
KW   DNA-directed RNA polymerase; Early protein; Host cytoplasm; Transcription;
KW   Viral transcription; Virion.
FT   CHAIN           1..335
FT                   /note="DNA-directed RNA polymerase RPB7 homolog"
FT                   /id="PRO_0000373655"
SQ   SEQUENCE   335 AA;  38266 MW;  719B78C94886F40F CRC64;
     MIDQKIFETT LNIDDPANFC TNVEAHLLKE LENIYVGKCF KNSFILNITG VIQRSPCFIM
     RTNNSGRGYM HVRFSALVSC LNAFDLIAAV KIIKNDSNII LGESLLTEPV TIVIPSSESQ
     NNVAEVGQIV PVQLANSSVY YIPGRQQASA TGSIFIPKHT FSVYHVQEEL TQEQALNLTK
     LVNIIEMLLE SRSKKDFKQI CFFEKLYYTY SINSDEILDL KIWKGPKGKE MARLKPCNVL
     SFLYDALKNK SSSLGFWARP PDLFKSSPLA YQQDQNSFNT TELPIICSAE VMFVTLLKEI
     INYLQFMNDL CDTFNNEQLI KRHENIWMLI EQKKI