RPB7_SOYBN
ID RPB7_SOYBN Reviewed; 176 AA.
AC P46279;
DT 01-NOV-1995, integrated into UniProtKB/Swiss-Prot.
DT 01-NOV-1995, sequence version 1.
DT 03-AUG-2022, entry version 109.
DE RecName: Full=DNA-directed RNA polymerase II subunit RPB7;
DE Short=RNA polymerase II subunit B7;
OS Glycine max (Soybean) (Glycine hispida).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; fabids; Fabales; Fabaceae; Papilionoideae; 50 kb inversion clade;
OC NPAAA clade; indigoferoid/millettioid clade; Phaseoleae; Glycine;
OC Glycine subgen. Soja.
OX NCBI_TaxID=3847;
RN [1]
RP NUCLEOTIDE SEQUENCE [MRNA].
RX PubMed=1429663; DOI=10.1016/s0021-9258(18)50071-5;
RA Ulmasov T.N., Guilfoyle T.J.;
RT "Sequence of the fifth largest subunit of RNA polymerase II from plants.";
RL J. Biol. Chem. 267:23165-23169(1992).
CC -!- FUNCTION: DNA-dependent RNA polymerase catalyzes the transcription of
CC DNA into RNA using the four ribonucleoside triphosphates as substrates.
CC Component of RNA polymerase II which synthesizes mRNA precursors and
CC many functional non-coding RNAs. Pol II is the central component of the
CC basal RNA polymerase II transcription machinery. It is composed of
CC mobile elements that move relative to each other. RPB7 is part of a
CC subcomplex with RPB4 that binds to a pocket formed by RPB1, RPB2 and
CC RPB6 at the base of the clamp element. The RBP4-RPB7 subcomplex seems
CC to lock the clamp via RPB7 in the closed conformation thus preventing
CC double-stranded DNA to enter the active site cleft. The RPB4-RPB7
CC subcomplex binds single-stranded DNA and RNA (By similarity).
CC {ECO:0000250}.
CC -!- SUBUNIT: Component of the RNA polymerase II (Pol II) complex consisting
CC of 12 subunits. RPB4 and RPB7 form a subcomplex that protrudes from the
CC 10-subunit Pol II core complex (By similarity). {ECO:0000250}.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000250}.
CC -!- SIMILARITY: Belongs to the eukaryotic RPB7/RPC8 RNA polymerase subunit
CC family. {ECO:0000305}.
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DR EMBL; M90504; AAA34005.1; -; mRNA.
DR PIR; B44457; B44457.
DR RefSeq; NP_001236982.1; NM_001250053.1.
DR RefSeq; XP_003524800.1; XM_003524752.3.
DR RefSeq; XP_014631122.1; XM_014775636.1.
DR RefSeq; XP_014631123.1; XM_014775637.1.
DR AlphaFoldDB; P46279; -.
DR SMR; P46279; -.
DR STRING; 3847.GLYMA08G09000.1; -.
DR PRIDE; P46279; -.
DR EnsemblPlants; KRH42356; KRH42356; GLYMA_08G085100.
DR EnsemblPlants; KRH42357; KRH42357; GLYMA_08G085100.
DR EnsemblPlants; KRH42358; KRH42358; GLYMA_08G085100.
DR EnsemblPlants; KRH58473; KRH58473; GLYMA_05G130300.
DR EnsemblPlants; KRH58474; KRH58474; GLYMA_05G130300.
DR EnsemblPlants; KRH58475; KRH58475; GLYMA_05G130300.
DR GeneID; 100793057; -.
DR GeneID; 547985; -.
DR Gramene; KRH42356; KRH42356; GLYMA_08G085100.
DR Gramene; KRH42357; KRH42357; GLYMA_08G085100.
DR Gramene; KRH42358; KRH42358; GLYMA_08G085100.
DR Gramene; KRH58473; KRH58473; GLYMA_05G130300.
DR Gramene; KRH58474; KRH58474; GLYMA_05G130300.
DR Gramene; KRH58475; KRH58475; GLYMA_05G130300.
DR KEGG; gmx:100793057; -.
DR KEGG; gmx:547985; -.
DR eggNOG; KOG3298; Eukaryota.
DR HOGENOM; CLU_085878_2_0_1; -.
DR InParanoid; P46279; -.
DR OMA; MRQPGLG; -.
DR OrthoDB; 1140388at2759; -.
DR Proteomes; UP000008827; Chromosome 5.
DR Proteomes; UP000008827; Chromosome 8.
DR Genevisible; P46279; GM.
DR GO; GO:0000932; C:P-body; IBA:GO_Central.
DR GO; GO:0005665; C:RNA polymerase II, core complex; IBA:GO_Central.
DR GO; GO:0003697; F:single-stranded DNA binding; IBA:GO_Central.
DR GO; GO:0003727; F:single-stranded RNA binding; IBA:GO_Central.
DR GO; GO:0031369; F:translation initiation factor binding; IBA:GO_Central.
DR GO; GO:0000291; P:nuclear-transcribed mRNA catabolic process, exonucleolytic; IBA:GO_Central.
DR GO; GO:0060213; P:positive regulation of nuclear-transcribed mRNA poly(A) tail shortening; IBA:GO_Central.
DR GO; GO:0045948; P:positive regulation of translational initiation; IBA:GO_Central.
DR GO; GO:0006367; P:transcription initiation from RNA polymerase II promoter; IBA:GO_Central.
DR Gene3D; 2.40.50.140; -; 1.
DR Gene3D; 3.30.1490.120; -; 1.
DR InterPro; IPR012340; NA-bd_OB-fold.
DR InterPro; IPR036898; RNA_pol_Rpb7-like_N_sf.
DR InterPro; IPR045113; Rpb7-like.
DR InterPro; IPR005576; Rpb7-like_N.
DR InterPro; IPR003029; S1_domain.
DR PANTHER; PTHR12709; PTHR12709; 1.
DR Pfam; PF00575; S1; 1.
DR Pfam; PF03876; SHS2_Rpb7-N; 1.
DR SUPFAM; SSF50249; SSF50249; 1.
DR SUPFAM; SSF88798; SSF88798; 1.
PE 2: Evidence at transcript level;
KW DNA-directed RNA polymerase; Nucleus; Reference proteome; Transcription.
FT CHAIN 1..176
FT /note="DNA-directed RNA polymerase II subunit RPB7"
FT /id="PRO_0000073991"
SQ SEQUENCE 176 AA; 19625 MW; FCCE9AAB096BEB36 CRC64;
MFFHIVLERN MQLHPRYFGR NLRDNLVSKL MKDVEGTCSG RHGFVVAVTG IENIGKGLIR
DGTGFVTFPV KYQCVVFRPF KGEILEAVVT MVNKMGFFAE AGPVQIFVSN HLIPDDMEFQ
SGDMPNYTTS DGSVKIQKDS EVRLKIIGTR VDATEIFCIG TIKDDFLGVI NDPATV
