ID   RPC19_DICDI             Reviewed;         116 AA.
AC   Q54ES6;
DT   24-NOV-2009, integrated into UniProtKB/Swiss-Prot.
DT   24-MAY-2005, sequence version 1.
DT   25-MAY-2022, entry version 94.
DE   RecName: Full=DNA-directed RNA polymerases I and III subunit rpc19;
GN   Name=rpc19; ORFNames=DDB_G0291362;
OS   Dictyostelium discoideum (Slime mold).
OC   Eukaryota; Amoebozoa; Evosea; Eumycetozoa; Dictyostelia; Dictyosteliales;
OC   Dictyosteliaceae; Dictyostelium.
OX   NCBI_TaxID=44689;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=AX4;
RX   PubMed=15875012; DOI=10.1038/nature03481;
RA   Eichinger L., Pachebat J.A., Gloeckner G., Rajandream M.A., Sucgang R.,
RA   Berriman M., Song J., Olsen R., Szafranski K., Xu Q., Tunggal B.,
RA   Kummerfeld S., Madera M., Konfortov B.A., Rivero F., Bankier A.T.,
RA   Lehmann R., Hamlin N., Davies R., Gaudet P., Fey P., Pilcher K., Chen G.,
RA   Saunders D., Sodergren E.J., Davis P., Kerhornou A., Nie X., Hall N.,
RA   Anjard C., Hemphill L., Bason N., Farbrother P., Desany B., Just E.,
RA   Morio T., Rost R., Churcher C.M., Cooper J., Haydock S., van Driessche N.,
RA   Cronin A., Goodhead I., Muzny D.M., Mourier T., Pain A., Lu M., Harper D.,
RA   Lindsay R., Hauser H., James K.D., Quiles M., Madan Babu M., Saito T.,
RA   Buchrieser C., Wardroper A., Felder M., Thangavelu M., Johnson D.,
RA   Knights A., Loulseged H., Mungall K.L., Oliver K., Price C., Quail M.A.,
RA   Urushihara H., Hernandez J., Rabbinowitsch E., Steffen D., Sanders M.,
RA   Ma J., Kohara Y., Sharp S., Simmonds M.N., Spiegler S., Tivey A.,
RA   Sugano S., White B., Walker D., Woodward J.R., Winckler T., Tanaka Y.,
RA   Shaulsky G., Schleicher M., Weinstock G.M., Rosenthal A., Cox E.C.,
RA   Chisholm R.L., Gibbs R.A., Loomis W.F., Platzer M., Kay R.R.,
RA   Williams J.G., Dear P.H., Noegel A.A., Barrell B.G., Kuspa A.;
RT   "The genome of the social amoeba Dictyostelium discoideum.";
RL   Nature 435:43-57(2005).
CC   -!- FUNCTION: DNA-dependent RNA polymerase catalyzes the transcription of
CC       DNA into RNA using the four ribonucleoside triphosphates as substrates.
CC       Common core component of RNA polymerases I and III which synthesize
CC       ribosomal RNA precursors and small RNAs, such as 5S rRNA and tRNAs,
CC       respectively (By similarity). {ECO:0000250}.
CC   -!- SUBUNIT: Component of the RNA polymerase I (Pol I) and RNA polymerase
CC       III (Pol III) complexes consisting of 14 and 17 subunits, respectively.
CC       {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the archaeal Rpo11/eukaryotic RPB11/RPC19 RNA
CC       polymerase subunit family. {ECO:0000305}.
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DR   EMBL; AAFI02000177; EAL61665.1; -; Genomic_DNA.
DR   RefSeq; XP_635164.1; XM_630072.1.
DR   AlphaFoldDB; Q54ES6; -.
DR   SMR; Q54ES6; -.
DR   STRING; 44689.DDB0216286; -.
DR   PaxDb; Q54ES6; -.
DR   EnsemblProtists; EAL61665; EAL61665; DDB_G0291362.
DR   GeneID; 8628110; -.
DR   KEGG; ddi:DDB_G0291362; -.
DR   dictyBase; DDB_G0291362; rpc19.
DR   eggNOG; KOG3438; Eukaryota.
DR   HOGENOM; CLU_090381_3_0_1; -.
DR   InParanoid; Q54ES6; -.
DR   OMA; MRIQMYD; -.
DR   PhylomeDB; Q54ES6; -.
DR   PRO; PR:Q54ES6; -.
DR   Proteomes; UP000002195; Chromosome 6.
DR   GO; GO:0005736; C:RNA polymerase I complex; ISS:dictyBase.
DR   GO; GO:0005666; C:RNA polymerase III complex; ISS:dictyBase.
DR   GO; GO:0003677; F:DNA binding; IEA:InterPro.
DR   GO; GO:0003899; F:DNA-directed 5'-3' RNA polymerase activity; ISS:dictyBase.
DR   GO; GO:0046983; F:protein dimerization activity; IEA:InterPro.
DR   GO; GO:0006360; P:transcription by RNA polymerase I; ISS:dictyBase.
DR   GO; GO:0006383; P:transcription by RNA polymerase III; ISS:dictyBase.
DR   CDD; cd07029; RNAP_I_III_AC19; 1.
DR   Gene3D; 3.30.1360.10; -; 1.
DR   HAMAP; MF_00261; RNApol_arch_Rpo11; 1.
DR   InterPro; IPR036603; RBP11-like.
DR   InterPro; IPR009025; RBP11-like_dimer.
DR   InterPro; IPR008193; RNA_pol_Rpb11_13-16kDa_CS.
DR   InterPro; IPR033898; RNAP_AC19.
DR   Pfam; PF13656; RNA_pol_L_2; 1.
DR   SUPFAM; SSF55257; SSF55257; 1.
DR   PROSITE; PS01154; RNA_POL_L_13KD; 1.
PE   3: Inferred from homology;
KW   DNA-directed RNA polymerase; Nucleus; Reference proteome; Transcription.
FT   CHAIN           1..116
FT                   /note="DNA-directed RNA polymerases I and III subunit
FT                   rpc19"
FT                   /id="PRO_0000389019"
SQ   SEQUENCE   116 AA;  12959 MW;  2C12D2AA60073DDC CRC64;
     MTLASAPAAT ESCNSFIPPS FDVNKVEIIS DRPDCATFIF TDEDHTLGNA LHYVLMKNPK
     VDFSGYSIPH PSDNRMNLRI QTKSNITAQE SLLQGLTDIK DISRHIFETF NNALDQ