ID   RPC1_BPHK0              Reviewed;         235 AA.
AC   P18680;
DT   01-NOV-1990, integrated into UniProtKB/Swiss-Prot.
DT   01-FEB-1996, sequence version 2.
DT   23-FEB-2022, entry version 91.
DE   RecName: Full=26 kDa repressor protein;
DE   AltName: Full=Regulatory protein CI;
GN   Name=CI-HTT;
OS   Escherichia phage HK022 (Bacteriophage HK022).
OC   Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes;
OC   Caudovirales; Siphoviridae; Hendrixvirinae; Shamshuipovirus.
OX   NCBI_TaxID=10742;
OH   NCBI_TaxID=562; Escherichia coli.
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RX   PubMed=2760929; DOI=10.1016/0022-2836(89)90237-4;
RA   Oberto J., Weisberg R.A., Gottesman M.E.;
RT   "Structure and function of the nun gene and the immunity region of the
RT   lambdoid phage HK022.";
RL   J. Mol. Biol. 207:675-693(1989).
RN   [2]
RP   SEQUENCE REVISION TO C-TERMINUS.
RA   Oberto J.;
RL   Submitted (DEC-1993) to the EMBL/GenBank/DDBJ databases.
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DR   EMBL; X16093; CAA34222.1; -; Genomic_DNA.
DR   PIR; S06541; Z1BPHK.
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   CDD; cd00093; HTH_XRE; 1.
DR   CDD; cd06529; S24_LexA-like; 1.
DR   Gene3D; 1.10.260.40; -; 1.
DR   InterPro; IPR001387; Cro/C1-type_HTH.
DR   InterPro; IPR010982; Lambda_DNA-bd_dom_sf.
DR   InterPro; IPR039418; LexA-like.
DR   InterPro; IPR036286; LexA/Signal_pep-like_sf.
DR   InterPro; IPR015927; Peptidase_S24_S26A/B/C.
DR   Pfam; PF01381; HTH_3; 1.
DR   Pfam; PF00717; Peptidase_S24; 1.
DR   SMART; SM00530; HTH_XRE; 1.
DR   SUPFAM; SSF47413; SSF47413; 1.
DR   SUPFAM; SSF51306; SSF51306; 1.
DR   PROSITE; PS50943; HTH_CROC1; 1.
PE   4: Predicted;
KW   DNA-binding; Repressor; Transcription; Transcription regulation.
FT   CHAIN           1..235
FT                   /note="26 kDa repressor protein"
FT                   /id="PRO_0000149711"
FT   DOMAIN          14..72
FT                   /note="HTH cro/C1-type"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00257"
FT   DNA_BIND        25..44
FT                   /note="H-T-H motif"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00257"
SQ   SEQUENCE   235 AA;  26512 MW;  194B5B368B6D08C5 CRC64;
     MVQQKERETF SQRLALACDK AGLPLHGRQA DLAVRLKVTP KAISKWFNGE SIPRKDKMES
     LASVLGTTAA YLHGYADDDG ITVNHLSRSN DYYRVDVLDV QASAGPGTMV SNEFIEKIRA
     IEYTTEQARI LFNGRPQESV KVITVRGDSM EGTINPGDEI FVDVSITCFD GDGIYVFVYG
     KTMHVKRLQM QKNRLAVISD NAAYDRWYIE EGEEEQLHIL AKVLIRQSID YKRFG