ID   RPC1_BPP22              Reviewed;          92 AA.
AC   P03041; Q7PCF0;
DT   21-JUL-1986, integrated into UniProtKB/Swiss-Prot.
DT   21-JUL-1986, sequence version 1.
DT   25-MAY-2022, entry version 110.
DE   RecName: Full=Transcriptional activator protein C1;
GN   Name=C1;
OS   Salmonella phage P22 (Bacteriophage P22).
OC   Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes;
OC   Caudovirales; Podoviridae; Lederbergvirus.
OX   NCBI_TaxID=10754;
OH   NCBI_TaxID=90371; Salmonella typhimurium.
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RX   PubMed=6241581; DOI=10.1016/0378-1119(84)90004-0;
RA   Backhaus H., Petri J.B.;
RT   "Sequence analysis of a region from the early right operon in phage P22
RT   including the replication genes 18 and 12.";
RL   Gene 32:289-303(1984).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RX   PubMed=3954988; DOI=10.1021/bi00349a035;
RA   Poteete A.R., Hehir K., Sauer R.T.;
RT   "Bacteriophage P22 Cro protein: sequence, purification, and properties.";
RL   Biochemistry 25:251-256(1986).
RN   [3]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX   PubMed=11053393; DOI=10.1128/jb.182.22.6472-6481.2000;
RA   Vander Byl C.S., Kropinski A.M.B.;
RT   "Sequence of the genome of Salmonella bacteriophage P22.";
RL   J. Bacteriol. 182:6472-6481(2000).
RN   [4]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX   PubMed=12562822; DOI=10.1128/jb.185.4.1475-1477.2003;
RA   Pedulla M.L., Ford M.E., Karthikeyan T., Houtz J.M., Hendrix R.W.,
RA   Hatfull G.F., Poteete A.R., Gilcrease E.B., Winn-Stapley D.A.,
RA   Casjens S.R.;
RT   "Corrected sequence of the bacteriophage P22 genome.";
RL   J. Bacteriol. 185:1475-1477(2003).
RN   [5]
RP   PROTEIN SEQUENCE OF 1-84, AND CHARACTERIZATION.
RX   PubMed=1385814; DOI=10.1016/s0021-9258(19)49724-x;
RA   Ho Y.S., Pfarr D., Strickler J., Rosenberg M.;
RT   "Characterization of the transcription activator protein C1 of
RT   bacteriophage P22.";
RL   J. Biol. Chem. 267:14388-14397(1992).
CC   -!- FUNCTION: Binds to two promoters, P(RE) and Pa23 and activate
CC       transcription from these promoters.
CC   -!- SUBUNIT: Homotetramer.
CC   -!- SIMILARITY: Belongs to the lambda phage CII protein family.
CC       {ECO:0000305}.
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DR   EMBL; M10074; AAA32274.1; -; Genomic_DNA.
DR   EMBL; M12584; AAA32269.1; -; Genomic_DNA.
DR   EMBL; AF217253; AAF75026.1; -; Genomic_DNA.
DR   EMBL; BK000583; DAA01023.1; -; Genomic_DNA.
DR   PIR; A91518; Z1BPC2.
DR   RefSeq; NP_059608.1; NC_002371.2.
DR   SMR; P03041; -.
DR   GeneID; 1262826; -.
DR   KEGG; vg:1262826; -.
DR   Proteomes; UP000001795; Genome.
DR   Proteomes; UP000007960; Genome.
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IEA:InterPro.
DR   CDD; cd00093; HTH_XRE; 1.
DR   Gene3D; 1.10.260.40; -; 1.
DR   InterPro; IPR001387; Cro/C1-type_HTH.
DR   InterPro; IPR010982; Lambda_DNA-bd_dom_sf.
DR   InterPro; IPR007933; Transcrpt_activ_CII.
DR   Pfam; PF05269; Phage_CII; 1.
DR   SUPFAM; SSF47413; SSF47413; 1.
PE   1: Evidence at protein level;
KW   Activator; Direct protein sequencing; DNA-binding; Reference proteome;
KW   Transcription; Transcription regulation.
FT   CHAIN           1..92
FT                   /note="Transcriptional activator protein C1"
FT                   /id="PRO_0000077590"
FT   DNA_BIND        26..45
FT                   /note="H-T-H motif"
FT                   /evidence="ECO:0000255"
FT   CONFLICT        83
FT                   /note="P -> D (in Ref. 5; AA sequence)"
FT                   /evidence="ECO:0000305"
SQ   SEQUENCE   92 AA;  10211 MW;  D479C6D90085CEE6 CRC64;
     MELTSTRKKA NAITSSILNR IAIRGQRKVA DALGINESQI SRWKGDFIPK MGMLLAVLEW
     GVEDEELAEL AKKVAHLLTK EKPQDCGNSF EA