ID   RPC1_BPPH8              Reviewed;         236 AA.
AC   P14819;
DT   01-APR-1990, integrated into UniProtKB/Swiss-Prot.
DT   23-JAN-2007, sequence version 2.
DT   07-OCT-2020, entry version 97.
DE   RecName: Full=Repressor protein CI;
GN   Name=CI;
OS   Enterobacteria phage phi80 (Bacteriophage phi-80).
OC   Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes;
OC   Caudovirales; Siphoviridae.
OX   NCBI_TaxID=10713;
OH   NCBI_TaxID=562; Escherichia coli.
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RX   PubMed=3172225; DOI=10.1016/0022-2836(88)90284-7;
RA   Ogawa T., Ogawa H., Tomizawa J.;
RT   "Organization of the early region of bacteriophage phi 80. Genes and
RT   proteins.";
RL   J. Mol. Biol. 202:537-550(1988).
RN   [2]
RP   PROTEIN SEQUENCE OF 2-6.
RX   PubMed=3172227; DOI=10.1016/0022-2836(88)90286-0;
RA   Eguchi Y., Ogawa T., Ogawa H.;
RT   "Cleavage of bacteriophage phi 80 CI repressor by RecA protein.";
RL   J. Mol. Biol. 202:565-573(1988).
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DR   EMBL; X13065; CAA31471.1; -; Genomic_DNA.
DR   PIR; S04828; S04828.
DR   RefSeq; YP_007947968.1; NC_021190.1.
DR   GeneID; 24366479; -.
DR   KEGG; vg:24366479; -.
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0045892; P:negative regulation of transcription, DNA-templated; IEA:InterPro.
DR   CDD; cd00093; HTH_XRE; 1.
DR   CDD; cd06529; S24_LexA-like; 1.
DR   Gene3D; 1.10.260.40; -; 1.
DR   InterPro; IPR001387; Cro/C1-type_HTH.
DR   InterPro; IPR010982; Lambda_DNA-bd_dom_sf.
DR   InterPro; IPR039418; LexA-like.
DR   InterPro; IPR036286; LexA/Signal_pep-like_sf.
DR   InterPro; IPR015927; Peptidase_S24_S26A/B/C.
DR   InterPro; IPR010744; Phage_CI_repr.
DR   Pfam; PF00717; Peptidase_S24; 1.
DR   Pfam; PF07022; Phage_CI_repr; 1.
DR   SMART; SM00530; HTH_XRE; 1.
DR   SUPFAM; SSF47413; SSF47413; 1.
DR   SUPFAM; SSF51306; SSF51306; 1.
DR   PROSITE; PS50943; HTH_CROC1; 1.
PE   1: Evidence at protein level;
KW   Direct protein sequencing; DNA-binding; Early protein; Repressor;
KW   Transcription; Transcription regulation.
FT   INIT_MET        1
FT                   /note="Removed; by host"
FT                   /evidence="ECO:0000269|PubMed:3172227"
FT   CHAIN           2..236
FT                   /note="Repressor protein CI"
FT                   /id="PRO_0000149712"
FT   DOMAIN          8..61
FT                   /note="HTH cro/C1-type"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00257"
FT   DNA_BIND        19..38
FT                   /note="H-T-H motif"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00257"
SQ   SEQUENCE   236 AA;  26497 MW;  F1295C48EDB21B1C CRC64;
     MSSISERIKF LLAREGLKQR DLAEALSTSP QTVNNWIKRD ALSREAAQQI SEKFGYSLDW
     LLNGEGSPKK DLESNIPPES EWGTVDAWDK NTPLPDDEVE VPFLKDIEFA CGDGRVHDED
     HNGFKLRFSK ATLRRVGANS DGSGVLCFPA SGDSMEPVIP DGATVAVDTG NKRVIDGELY
     AINQGDLKRI KQLYRKPGGK ILIRSINRDY DDEEADEADV EIIGFVFWYS VLRYRR