ID   RPC2_BP186              Reviewed;         169 AA.
AC   P21678;
DT   01-MAY-1991, integrated into UniProtKB/Swiss-Prot.
DT   01-MAY-1991, sequence version 1.
DT   25-MAY-2022, entry version 77.
DE   RecName: Full=Regulatory protein CII;
GN   Name=CII; Synonyms=CP76;
OS   Escherichia phage 186 (Bacteriophage 186).
OC   Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes;
OC   Caudovirales; Myoviridae; Peduovirinae; Eganvirus.
OX   NCBI_TaxID=29252;
OH   NCBI_TaxID=562; Escherichia coli.
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RX   PubMed=2704042; DOI=10.1016/0022-2836(89)90539-1;
RA   Richardson H., Puspurs A., Egan J.B.;
RT   "Control of gene expression in the P2-related temperate coliphage 186. VI.
RT   Sequence analysis of the early lytic region.";
RL   J. Mol. Biol. 206:251-255(1989).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA] OF 1-147.
RC   STRAIN=186CITSP;
RX   PubMed=3806670; DOI=10.1016/0022-2836(86)90257-3;
RA   Kalionis B., Dodd I.B., Egan J.B.;
RT   "Control of gene expression in the P2-related template coliphages. III. DNA
RT   sequence of the major control region of phage 186.";
RL   J. Mol. Biol. 191:199-209(1986).
CC   -!- FUNCTION: Involved in the establishment of lysogeny.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; X15001; CAA33106.1; -; Genomic_DNA.
DR   EMBL; U32222; AAC34178.1; -; Genomic_DNA.
DR   PIR; S03593; S03593.
DR   RefSeq; NP_052281.1; NC_001317.1.
DR   PDB; 6VLI; X-ray; 2.10 A; A/B/C/D=1-145.
DR   PDB; 6VMH; X-ray; 2.75 A; B/C=1-135.
DR   PDB; 6VPE; X-ray; 2.21 A; A/B=1-145.
DR   PDBsum; 6VLI; -.
DR   PDBsum; 6VMH; -.
DR   PDBsum; 6VPE; -.
DR   SMR; P21678; -.
DR   GeneID; 1262431; -.
DR   KEGG; vg:1262431; -.
DR   Proteomes; UP000000369; Genome.
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   InterPro; IPR009679; Phage_186_CII.
DR   Pfam; PF06892; Phage_CP76; 1.
PE   1: Evidence at protein level;
KW   3D-structure; Activator; DNA-binding; Early protein; Reference proteome;
KW   Transcription; Transcription regulation.
FT   CHAIN           1..169
FT                   /note="Regulatory protein CII"
FT                   /id="PRO_0000165293"
FT   STRAND          2..4
FT                   /evidence="ECO:0007829|PDB:6VLI"
FT   HELIX           11..22
FT                   /evidence="ECO:0007829|PDB:6VLI"
FT   HELIX           25..32
FT                   /evidence="ECO:0007829|PDB:6VLI"
FT   HELIX           36..42
FT                   /evidence="ECO:0007829|PDB:6VLI"
FT   HELIX           53..63
FT                   /evidence="ECO:0007829|PDB:6VLI"
FT   HELIX           67..75
FT                   /evidence="ECO:0007829|PDB:6VLI"
FT   HELIX           92..111
FT                   /evidence="ECO:0007829|PDB:6VLI"
FT   HELIX           118..141
FT                   /evidence="ECO:0007829|PDB:6VLI"
FT   HELIX           142..144
FT                   /evidence="ECO:0007829|PDB:6VLI"
SQ   SEQUENCE   169 AA;  18692 MW;  9026AD6C0CA9D37C CRC64;
     MFDFQVSKHP HYDEACRAFA QRHNMAKLAE RAGMNVQTLR NKLNPEQPHQ FTPPELWLLT
     DLTEDSTLVD GFLAQIHCLP CVPVNELAKD KLQSYVMRAM SELGELASGA VSDERLTTAR
     KHNMIESVNS GIRMLSLSAL ALHARLQTNP AMSSVVDTMS GIGASFGLI