ID   RPC3_ASPCL              Reviewed;         635 AA.
AC   A1C4R7;
DT   23-SEP-2008, integrated into UniProtKB/Swiss-Prot.
DT   23-JAN-2007, sequence version 1.
DT   03-AUG-2022, entry version 70.
DE   RecName: Full=DNA-directed RNA polymerase III subunit rpc3;
DE            Short=RNA polymerase III subunit C3;
GN   Name=rpc82; Synonyms=rpc3; ORFNames=ACLA_000960;
OS   Aspergillus clavatus (strain ATCC 1007 / CBS 513.65 / DSM 816 / NCTC 3887 /
OS   NRRL 1 / QM 1276 / 107).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC   Eurotiomycetidae; Eurotiales; Aspergillaceae; Aspergillus;
OC   Aspergillus subgen. Fumigati.
OX   NCBI_TaxID=344612;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 1007 / CBS 513.65 / DSM 816 / NCTC 3887 / NRRL 1;
RX   PubMed=18404212; DOI=10.1371/journal.pgen.1000046;
RA   Fedorova N.D., Khaldi N., Joardar V.S., Maiti R., Amedeo P., Anderson M.J.,
RA   Crabtree J., Silva J.C., Badger J.H., Albarraq A., Angiuoli S., Bussey H.,
RA   Bowyer P., Cotty P.J., Dyer P.S., Egan A., Galens K., Fraser-Liggett C.M.,
RA   Haas B.J., Inman J.M., Kent R., Lemieux S., Malavazi I., Orvis J.,
RA   Roemer T., Ronning C.M., Sundaram J.P., Sutton G., Turner G., Venter J.C.,
RA   White O.R., Whitty B.R., Youngman P., Wolfe K.H., Goldman G.H.,
RA   Wortman J.R., Jiang B., Denning D.W., Nierman W.C.;
RT   "Genomic islands in the pathogenic filamentous fungus Aspergillus
RT   fumigatus.";
RL   PLoS Genet. 4:E1000046-E1000046(2008).
CC   -!- FUNCTION: DNA-dependent RNA polymerase catalyzes the transcription of
CC       DNA into RNA using the four ribonucleoside triphosphates as substrates.
CC       Specific core component of RNA polymerase III which synthesizes small
CC       RNAs, such as 5S rRNA and tRNAs (By similarity). {ECO:0000250}.
CC   -!- SUBUNIT: Component of the RNA polymerase III (Pol III) complex
CC       consisting of 17 subunits. {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the RNA polymerase beta chain family.
CC       {ECO:0000305}.
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DR   EMBL; DS027004; EAW14685.1; -; Genomic_DNA.
DR   RefSeq; XP_001276111.1; XM_001276110.1.
DR   AlphaFoldDB; A1C4R7; -.
DR   SMR; A1C4R7; -.
DR   STRING; 5057.CADACLAP00000212; -.
DR   EnsemblFungi; EAW14685; EAW14685; ACLA_000960.
DR   GeneID; 4708581; -.
DR   KEGG; act:ACLA_000960; -.
DR   VEuPathDB; FungiDB:ACLA_000960; -.
DR   eggNOG; KOG2587; Eukaryota.
DR   HOGENOM; CLU_023294_0_0_1; -.
DR   OMA; QLKMVNE; -.
DR   OrthoDB; 809282at2759; -.
DR   Proteomes; UP000006701; Unassembled WGS sequence.
DR   GO; GO:0005666; C:RNA polymerase III complex; IEA:InterPro.
DR   GO; GO:0003697; F:single-stranded DNA binding; IEA:InterPro.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:InterPro.
DR   Gene3D; 1.10.10.10; -; 2.
DR   InterPro; IPR013197; RNA_pol_III_RPC82-rel_HTH.
DR   InterPro; IPR008806; RNA_pol_III_Rpc82_C.
DR   InterPro; IPR039748; RPC3.
DR   InterPro; IPR036388; WH-like_DNA-bd_sf.
DR   InterPro; IPR036390; WH_DNA-bd_sf.
DR   PANTHER; PTHR12949; PTHR12949; 1.
DR   Pfam; PF08221; HTH_9; 1.
DR   Pfam; PF05645; RNA_pol_Rpc82; 1.
DR   SUPFAM; SSF46785; SSF46785; 1.
PE   3: Inferred from homology;
KW   DNA-directed RNA polymerase; Nucleus; Reference proteome; Transcription;
KW   Zinc.
FT   CHAIN           1..635
FT                   /note="DNA-directed RNA polymerase III subunit rpc3"
FT                   /id="PRO_0000351023"
FT   REGION          131..164
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          246..295
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          386..424
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          562..583
FT                   /note="Leucine-zipper"
FT   COMPBIAS        135..156
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        253..272
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        273..292
FT                   /note="Acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        397..411
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   635 AA;  72369 MW;  A5A9A664DA3F9D3F CRC64;
     MASQYAAELC ALLVEDNFGE LFARIFSTLT RYDRLNLPRL KFHSGLSNRQ LLPALAAMIQ
     QHLVYHYTSY DDGVTYYEAN LQSAYYLVRA GKILEFVEER LGKYAATVMS SIMYLGHAQV
     SHLENLPELQ PEQSHTNGVD KEHDEVDGDE EQPNGLSGDH SDQQPALLHP TLKVLAAHGY
     IIRVREAQFQ SHADNILDAE RVLKSRPEIK AMKGKRMEEA VIEGTLELLK ERTDGDLTRG
     LMVQGVPRGA KRKHGSKSAD APNKKARVDF ASVDEDDEQD EEENEWSDDE MGYDTTPMES
     GLVVRVNYNK LDVALRNCRF IQIAEQDASP ATAEVYECLL RRIEYQTHQC RDTVEIPREG
     EEGEQYSVPI ALSAVAEDVD PRLDLSGSIG PMEISQPDNR RGKRPLEDDV NGTNHEGANG
     LSSGGNRTFE VDQHLCLLAQ PPHNLTSKRI VSGLITWTVE FRHLARKLRH LELERMIEAR
     YGDVALRVVR VLHAKGKLDE KRLQEISLLP FKDLRQVLAS MQAGGFVDLQ EVPRDAQRQP
     SRTIYLWYYD PDRICNSVLQ DTYKAMSRCF QRLRFERNRL KEFLEKTERS DVKGNEERYL
     SEGELALLQQ WKAKEALLIG EVARLDEMVA VMRDY