ID   RPC3_CANGA              Reviewed;         666 AA.
AC   Q6FSJ4;
DT   23-SEP-2008, integrated into UniProtKB/Swiss-Prot.
DT   19-JUL-2004, sequence version 1.
DT   25-MAY-2022, entry version 86.
DE   RecName: Full=DNA-directed RNA polymerase III subunit RPC3;
DE            Short=RNA polymerase III subunit C3;
GN   Name=RPC82; Synonyms=RPC3; OrderedLocusNames=CAGL0G10109g;
OS   Candida glabrata (strain ATCC 2001 / CBS 138 / JCM 3761 / NBRC 0622 / NRRL
OS   Y-65) (Yeast) (Torulopsis glabrata).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC   Saccharomycetales; Saccharomycetaceae; Nakaseomyces;
OC   Nakaseomyces/Candida clade.
OX   NCBI_TaxID=284593;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 2001 / CBS 138 / JCM 3761 / NBRC 0622 / NRRL Y-65;
RX   PubMed=15229592; DOI=10.1038/nature02579;
RA   Dujon B., Sherman D., Fischer G., Durrens P., Casaregola S., Lafontaine I.,
RA   de Montigny J., Marck C., Neuveglise C., Talla E., Goffard N., Frangeul L.,
RA   Aigle M., Anthouard V., Babour A., Barbe V., Barnay S., Blanchin S.,
RA   Beckerich J.-M., Beyne E., Bleykasten C., Boisrame A., Boyer J.,
RA   Cattolico L., Confanioleri F., de Daruvar A., Despons L., Fabre E.,
RA   Fairhead C., Ferry-Dumazet H., Groppi A., Hantraye F., Hennequin C.,
RA   Jauniaux N., Joyet P., Kachouri R., Kerrest A., Koszul R., Lemaire M.,
RA   Lesur I., Ma L., Muller H., Nicaud J.-M., Nikolski M., Oztas S.,
RA   Ozier-Kalogeropoulos O., Pellenz S., Potier S., Richard G.-F.,
RA   Straub M.-L., Suleau A., Swennen D., Tekaia F., Wesolowski-Louvel M.,
RA   Westhof E., Wirth B., Zeniou-Meyer M., Zivanovic Y., Bolotin-Fukuhara M.,
RA   Thierry A., Bouchier C., Caudron B., Scarpelli C., Gaillardin C.,
RA   Weissenbach J., Wincker P., Souciet J.-L.;
RT   "Genome evolution in yeasts.";
RL   Nature 430:35-44(2004).
CC   -!- FUNCTION: DNA-dependent RNA polymerase catalyzes the transcription of
CC       DNA into RNA using the four ribonucleoside triphosphates as substrates.
CC       Specific core component of RNA polymerase III which synthesizes small
CC       RNAs, such as 5S rRNA and tRNAs (By similarity). {ECO:0000250}.
CC   -!- SUBUNIT: Component of the RNA polymerase III (Pol III) complex
CC       consisting of 17 subunits. {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the RNA polymerase beta chain family.
CC       {ECO:0000305}.
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DR   EMBL; CR380953; CAG59727.1; -; Genomic_DNA.
DR   RefSeq; XP_446800.1; XM_446800.1.
DR   AlphaFoldDB; Q6FSJ4; -.
DR   SMR; Q6FSJ4; -.
DR   STRING; 5478.XP_446800.1; -.
DR   EnsemblFungi; CAG59727; CAG59727; CAGL0G10109g.
DR   GeneID; 2887998; -.
DR   KEGG; cgr:CAGL0G10109g; -.
DR   CGD; CAL0130440; CAGL0G10109g.
DR   VEuPathDB; FungiDB:CAGL0G10109g; -.
DR   eggNOG; KOG2587; Eukaryota.
DR   HOGENOM; CLU_010734_0_0_1; -.
DR   InParanoid; Q6FSJ4; -.
DR   Proteomes; UP000002428; Chromosome G.
DR   GO; GO:0005666; C:RNA polymerase III complex; IEA:EnsemblFungi.
DR   GO; GO:0001056; F:RNA polymerase III activity; IEA:EnsemblFungi.
DR   GO; GO:0003697; F:single-stranded DNA binding; IEA:InterPro.
DR   GO; GO:0006386; P:termination of RNA polymerase III transcription; IEA:EnsemblFungi.
DR   GO; GO:0006384; P:transcription initiation from RNA polymerase III promoter; IEA:EnsemblFungi.
DR   GO; GO:0042797; P:tRNA transcription by RNA polymerase III; IEA:EnsemblFungi.
DR   Gene3D; 1.10.10.10; -; 2.
DR   InterPro; IPR013197; RNA_pol_III_RPC82-rel_HTH.
DR   InterPro; IPR008806; RNA_pol_III_Rpc82_C.
DR   InterPro; IPR039748; RPC3.
DR   InterPro; IPR036388; WH-like_DNA-bd_sf.
DR   PANTHER; PTHR12949; PTHR12949; 1.
DR   Pfam; PF08221; HTH_9; 1.
DR   Pfam; PF05645; RNA_pol_Rpc82; 1.
PE   3: Inferred from homology;
KW   DNA-directed RNA polymerase; Nucleus; Reference proteome; Transcription;
KW   Zinc.
FT   CHAIN           1..666
FT                   /note="DNA-directed RNA polymerase III subunit RPC3"
FT                   /id="PRO_0000351030"
FT   REGION          593..614
FT                   /note="Leucine-zipper"
SQ   SEQUENCE   666 AA;  76187 MW;  F16BAD32C7E5FA98 CRC64;
     MDILSDIKAS VKGAPAPQQN PAAIKSENGN VDVSVSNEIH QQTAASTEEL MSVSSLEQRT
     LHAEKFLYTE VIKSYLGERA STVISLLISL GRLTVREIYE KLNFTMSIDS IRRTLVSLTQ
     LRCVRYLEEP KRGSAKYNTY YYYNKDGVYL LLYSGLIIND ISSRFSEQKR PIVAEIIQNI
     LSLGSLSLND YLENVTYNIP KHEMSGLFVE LCEMGFLVRL TKFDYTPIKD LWNLLYEKEY
     NQLPRNSTQS DLKKRTEAKN KAKTEFHNLM EASTDLSKLI KLDPSTSLRT VIPTATLTIN
     IKRFLKSRRS LQLTNYARSR VGPVSAQLYK LALKLTENKA PYFNDILSET GLLQDLDELT
     AMSDEMELLE EKSPGVTFTA NDILKIVPKN YKIENSLVYE KKSGKRSQNQ EKSANTKRLK
     TEDGFVIPSL PTDNNHSNEK EIDDAEVEDG INEGDEMDAD SVSIINSHLK ILASSPVPFL
     KETQPNVYYI PYSNLIPELK SSIYDHIIVS TLGPPSLRIR RCIKENKLVS EKVINGTALM
     KEKDIRTTIG SLIKYNAVEI QEVPRTVDRS ASRAVFLFRC NESHSYNFMK QNLAWNLANL
     LYKKEKIEDE NKTLLMKANR DDVKGKEREL LLPSELNQLK MVNERELNIF TRSFRLMSLW
     EVFEFF