ID   RPC3_CHAGB              Reviewed;         628 AA.
AC   Q2GUW6;
DT   23-SEP-2008, integrated into UniProtKB/Swiss-Prot.
DT   21-MAR-2006, sequence version 1.
DT   03-AUG-2022, entry version 54.
DE   RecName: Full=DNA-directed RNA polymerase III subunit RPC3;
DE            Short=RNA polymerase III subunit C3;
GN   Name=RPC82; Synonyms=RPC3; ORFNames=CHGG_08238;
OS   Chaetomium globosum (strain ATCC 6205 / CBS 148.51 / DSM 1962 / NBRC 6347 /
OS   NRRL 1970) (Soil fungus).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Sordariomycetes;
OC   Sordariomycetidae; Sordariales; Chaetomiaceae; Chaetomium.
OX   NCBI_TaxID=306901;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 6205 / CBS 148.51 / DSM 1962 / NBRC 6347 / NRRL 1970;
RX   PubMed=25720678; DOI=10.1128/genomea.00021-15;
RA   Cuomo C.A., Untereiner W.A., Ma L.-J., Grabherr M., Birren B.W.;
RT   "Draft genome sequence of the cellulolytic fungus Chaetomium globosum.";
RL   Genome Announc. 3:E0002115-E0002115(2015).
CC   -!- FUNCTION: DNA-dependent RNA polymerase catalyzes the transcription of
CC       DNA into RNA using the four ribonucleoside triphosphates as substrates.
CC       Specific core component of RNA polymerase III which synthesizes small
CC       RNAs, such as 5S rRNA and tRNAs (By similarity). {ECO:0000250}.
CC   -!- SUBUNIT: Component of the RNA polymerase III (Pol III) complex
CC       consisting of 17 subunits. {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the RNA polymerase beta chain family.
CC       {ECO:0000305}.
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DR   EMBL; CH408033; EAQ86985.1; -; Genomic_DNA.
DR   RefSeq; XP_001225894.1; XM_001225893.1.
DR   AlphaFoldDB; Q2GUW6; -.
DR   SMR; Q2GUW6; -.
DR   STRING; 38033.XP_001225894.1; -.
DR   EnsemblFungi; EAQ86985; EAQ86985; CHGG_08238.
DR   GeneID; 4393570; -.
DR   eggNOG; KOG2587; Eukaryota.
DR   HOGENOM; CLU_023294_0_0_1; -.
DR   InParanoid; Q2GUW6; -.
DR   OMA; QLKMVNE; -.
DR   OrthoDB; 809282at2759; -.
DR   Proteomes; UP000001056; Unassembled WGS sequence.
DR   GO; GO:0005666; C:RNA polymerase III complex; IEA:InterPro.
DR   GO; GO:0003697; F:single-stranded DNA binding; IEA:InterPro.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:InterPro.
DR   Gene3D; 1.10.10.10; -; 2.
DR   InterPro; IPR008806; RNA_pol_III_Rpc82_C.
DR   InterPro; IPR039748; RPC3.
DR   InterPro; IPR036388; WH-like_DNA-bd_sf.
DR   PANTHER; PTHR12949; PTHR12949; 1.
DR   Pfam; PF05645; RNA_pol_Rpc82; 1.
PE   3: Inferred from homology;
KW   DNA-directed RNA polymerase; Nucleus; Reference proteome; Transcription;
KW   Zinc.
FT   CHAIN           1..628
FT                   /note="DNA-directed RNA polymerase III subunit RPC3"
FT                   /id="PRO_0000351031"
FT   REGION          360..422
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          555..576
FT                   /note="Leucine-zipper"
FT   COMPBIAS        361..381
FT                   /note="Acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        387..408
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   628 AA;  70458 MW;  19A12EF3E03B0BE9 CRC64;
     MTPRQVRHGL AVLQQHNLLF YHTDPGAEFA SYEANPDNAY NLVRTGKILE MIDTSFGAPA
     KDVMQSLLLS GQTRVSDLVA AYKEKIEQGN QTESTVGDDN DFGIEANGVN GDSKADKKAG
     PLIKSTAHLN TIICRLVEAE LIDVVHPKTF ESSEDILKTV EKEVMQKHFP AGVKGNKAKV
     ELQERIAEGL RKVRGESKSL KRKLEQNGSA AKRRKLLAGF GMANGAHDED MDPALDPRQV
     IRINYEKCLV DLRNRRLVQY ATDMTGETTA YVYGVLLKLL TKDLSRCRAD LVMDAVGDKD
     EEDDKGPGSV TTDQILDNLK TSVDLSLGIG KAERGQVSST AAEKIELYPP KKKVLIEEAE
     VDGEASADED EGEDESSEES DYDSDYKAST THGTNGVNGT NGTNGTKVKF DESAAPKERR
     MDRPAQLRQH LLMLAESTQH FVRHCGPNEW TVDFVPVMKS LREAELDSVI ERTCGRQGLR
     LVRILRAKGK LDEKALPNVA LMRKPELQQK MLEMQTAGFV SVQEVPRDLK ADVKKSFFLW
     FCDMDSSLSR LLDTGYVTMV HCLQVLEALR RKERDVLETT KRTDVRGREK DTMRKSYYER
     YSRFLESERK LFAQVMRVDD LVSVLRDF