ID   RPC3_DEBHA              Reviewed;         606 AA.
AC   Q6BQ18;
DT   23-SEP-2008, integrated into UniProtKB/Swiss-Prot.
DT   16-DEC-2008, sequence version 2.
DT   03-AUG-2022, entry version 85.
DE   RecName: Full=DNA-directed RNA polymerase III subunit RPC3;
DE            Short=RNA polymerase III subunit C3;
GN   Name=RPC82; Synonyms=RPC3; OrderedLocusNames=DEHA2E09064g;
OS   Debaryomyces hansenii (strain ATCC 36239 / CBS 767 / BCRC 21394 / JCM 1990
OS   / NBRC 0083 / IGC 2968) (Yeast) (Torulaspora hansenii).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC   Saccharomycetales; Debaryomycetaceae; Debaryomyces.
OX   NCBI_TaxID=284592;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 36239 / CBS 767 / BCRC 21394 / JCM 1990 / NBRC 0083 / IGC 2968;
RX   PubMed=15229592; DOI=10.1038/nature02579;
RA   Dujon B., Sherman D., Fischer G., Durrens P., Casaregola S., Lafontaine I.,
RA   de Montigny J., Marck C., Neuveglise C., Talla E., Goffard N., Frangeul L.,
RA   Aigle M., Anthouard V., Babour A., Barbe V., Barnay S., Blanchin S.,
RA   Beckerich J.-M., Beyne E., Bleykasten C., Boisrame A., Boyer J.,
RA   Cattolico L., Confanioleri F., de Daruvar A., Despons L., Fabre E.,
RA   Fairhead C., Ferry-Dumazet H., Groppi A., Hantraye F., Hennequin C.,
RA   Jauniaux N., Joyet P., Kachouri R., Kerrest A., Koszul R., Lemaire M.,
RA   Lesur I., Ma L., Muller H., Nicaud J.-M., Nikolski M., Oztas S.,
RA   Ozier-Kalogeropoulos O., Pellenz S., Potier S., Richard G.-F.,
RA   Straub M.-L., Suleau A., Swennen D., Tekaia F., Wesolowski-Louvel M.,
RA   Westhof E., Wirth B., Zeniou-Meyer M., Zivanovic Y., Bolotin-Fukuhara M.,
RA   Thierry A., Bouchier C., Caudron B., Scarpelli C., Gaillardin C.,
RA   Weissenbach J., Wincker P., Souciet J.-L.;
RT   "Genome evolution in yeasts.";
RL   Nature 430:35-44(2004).
CC   -!- FUNCTION: DNA-dependent RNA polymerase catalyzes the transcription of
CC       DNA into RNA using the four ribonucleoside triphosphates as substrates.
CC       Specific core component of RNA polymerase III which synthesizes small
CC       RNAs, such as 5S rRNA and tRNAs (By similarity). {ECO:0000250}.
CC   -!- SUBUNIT: Component of the RNA polymerase III (Pol III) complex
CC       consisting of 17 subunits. {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the RNA polymerase beta chain family.
CC       {ECO:0000305}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; CR382137; CAG87938.2; -; Genomic_DNA.
DR   RefSeq; XP_459702.2; XM_459702.1.
DR   AlphaFoldDB; Q6BQ18; -.
DR   SMR; Q6BQ18; -.
DR   STRING; 4959.XP_459702.2; -.
DR   EnsemblFungi; CAG87938; CAG87938; DEHA2E09064g.
DR   GeneID; 2901849; -.
DR   KEGG; dha:DEHA2E09064g; -.
DR   VEuPathDB; FungiDB:DEHA2E09064g; -.
DR   eggNOG; KOG2587; Eukaryota.
DR   HOGENOM; CLU_010734_0_0_1; -.
DR   InParanoid; Q6BQ18; -.
DR   OMA; QLKMVNE; -.
DR   OrthoDB; 809282at2759; -.
DR   Proteomes; UP000000599; Chromosome E.
DR   GO; GO:0005666; C:RNA polymerase III complex; IEA:InterPro.
DR   GO; GO:0003697; F:single-stranded DNA binding; IEA:InterPro.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:InterPro.
DR   Gene3D; 1.10.10.10; -; 2.
DR   InterPro; IPR013197; RNA_pol_III_RPC82-rel_HTH.
DR   InterPro; IPR008806; RNA_pol_III_Rpc82_C.
DR   InterPro; IPR039748; RPC3.
DR   InterPro; IPR036388; WH-like_DNA-bd_sf.
DR   PANTHER; PTHR12949; PTHR12949; 1.
DR   Pfam; PF08221; HTH_9; 1.
DR   Pfam; PF05645; RNA_pol_Rpc82; 1.
PE   3: Inferred from homology;
KW   DNA-directed RNA polymerase; Nucleus; Reference proteome; Transcription;
KW   Zinc.
FT   CHAIN           1..606
FT                   /note="DNA-directed RNA polymerase III subunit RPC3"
FT                   /id="PRO_0000351033"
FT   REGION          533..554
FT                   /note="Leucine-zipper"
SQ   SEQUENCE   606 AA;  69479 MW;  F0CA5913AE204DA1 CRC64;
     MNAVVPDSAK TQSAKSNLYT TLAKTHLGEV AAIIVSTLIS YGRLTAKDLS NKSEVPLKLV
     KSTLVSLIQL SCISYWKEES SKQVFYSFNE NGLLIFLHSG DIINHIKLTY GDESAGIIQN
     IIEVGHMKIE DYLQNIEDPE VVFNKENLLL KLFSDGWLSR VQMSNFQPID DLWNQLYQET
     LKNTPRSTTI SEIKRVNEAK DKTKLKFTNL LESGNSAKEL FQIENGIKKL APSLVIAFNL
     SRFEKHRRTE QLTNLAKARI GILTSKVYEC ALQLIEQHSP DLRHSFLKIS GLINDPVEEQ
     AFVNSIENQL VDDKKIVFNV KDLVKIAPKD LDLRNSILTH NFLKPTFNPK KRVNDDIPDT
     NPKKIKTEDG MNNLMIDLDP DVSENNLDFD MHNTDNSEPH SVSLINHHLK LLSSGVIPFL
     IEITPGTYTV PYTDLMKYVK QCNYDTLIKT TLGLDSFRLL RCLKSLKLAD EKTLANTILL
     KEKTVRNELF KLMNLNMIEI QEVPRSADRA ASKTFYLFRH KEFSAYNFLY NSLTFCMADI
     LSNIQQFKND NKILLEKCER EDVKGNEEEL LLESELKTLK NLQLREINNI GKFNRIKTLY
     EIFDNF