ID   RPC3_LODEL              Reviewed;         610 AA.
AC   A5DRM4;
DT   23-SEP-2008, integrated into UniProtKB/Swiss-Prot.
DT   12-JUN-2007, sequence version 1.
DT   03-AUG-2022, entry version 68.
DE   RecName: Full=DNA-directed RNA polymerase III subunit RPC3;
DE            Short=RNA polymerase III subunit C3;
GN   Name=RPC82; Synonyms=RPC3; ORFNames=LELG_00010;
OS   Lodderomyces elongisporus (strain ATCC 11503 / CBS 2605 / JCM 1781 / NBRC
OS   1676 / NRRL YB-4239) (Yeast) (Saccharomyces elongisporus).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC   Saccharomycetales; Debaryomycetaceae; Candida/Lodderomyces clade;
OC   Lodderomyces.
OX   NCBI_TaxID=379508;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 11503 / BCRC 21390 / CBS 2605 / JCM 1781 / NBRC 1676 / NRRL
RC   YB-4239;
RX   PubMed=19465905; DOI=10.1038/nature08064;
RA   Butler G., Rasmussen M.D., Lin M.F., Santos M.A.S., Sakthikumar S.,
RA   Munro C.A., Rheinbay E., Grabherr M., Forche A., Reedy J.L., Agrafioti I.,
RA   Arnaud M.B., Bates S., Brown A.J.P., Brunke S., Costanzo M.C.,
RA   Fitzpatrick D.A., de Groot P.W.J., Harris D., Hoyer L.L., Hube B.,
RA   Klis F.M., Kodira C., Lennard N., Logue M.E., Martin R., Neiman A.M.,
RA   Nikolaou E., Quail M.A., Quinn J., Santos M.C., Schmitzberger F.F.,
RA   Sherlock G., Shah P., Silverstein K.A.T., Skrzypek M.S., Soll D.,
RA   Staggs R., Stansfield I., Stumpf M.P.H., Sudbery P.E., Srikantha T.,
RA   Zeng Q., Berman J., Berriman M., Heitman J., Gow N.A.R., Lorenz M.C.,
RA   Birren B.W., Kellis M., Cuomo C.A.;
RT   "Evolution of pathogenicity and sexual reproduction in eight Candida
RT   genomes.";
RL   Nature 459:657-662(2009).
CC   -!- FUNCTION: DNA-dependent RNA polymerase catalyzes the transcription of
CC       DNA into RNA using the four ribonucleoside triphosphates as substrates.
CC       Specific core component of RNA polymerase III which synthesizes small
CC       RNAs, such as 5S rRNA and tRNAs (By similarity). {ECO:0000250}.
CC   -!- SUBUNIT: Component of the RNA polymerase III (Pol III) complex
CC       consisting of 17 subunits. {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the RNA polymerase beta chain family.
CC       {ECO:0000305}.
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DR   EMBL; CH981524; EDK41832.1; -; Genomic_DNA.
DR   RefSeq; XP_001527490.1; XM_001527440.1.
DR   AlphaFoldDB; A5DRM4; -.
DR   SMR; A5DRM4; -.
DR   STRING; 379508.A5DRM4; -.
DR   EnsemblFungi; EDK41832; EDK41832; LELG_00010.
DR   GeneID; 5235812; -.
DR   KEGG; lel:LELG_00010; -.
DR   VEuPathDB; FungiDB:LELG_00010; -.
DR   eggNOG; KOG2587; Eukaryota.
DR   HOGENOM; CLU_010734_0_0_1; -.
DR   InParanoid; A5DRM4; -.
DR   OMA; QLKMVNE; -.
DR   OrthoDB; 809282at2759; -.
DR   Proteomes; UP000001996; Unassembled WGS sequence.
DR   GO; GO:0005666; C:RNA polymerase III complex; IEA:InterPro.
DR   GO; GO:0003697; F:single-stranded DNA binding; IEA:InterPro.
DR   GO; GO:0044182; P:filamentous growth of a population of unicellular organisms; IEA:UniProt.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:InterPro.
DR   Gene3D; 1.10.10.10; -; 2.
DR   InterPro; IPR013197; RNA_pol_III_RPC82-rel_HTH.
DR   InterPro; IPR008806; RNA_pol_III_Rpc82_C.
DR   InterPro; IPR039748; RPC3.
DR   InterPro; IPR036388; WH-like_DNA-bd_sf.
DR   PANTHER; PTHR12949; PTHR12949; 1.
DR   Pfam; PF08221; HTH_9; 1.
DR   Pfam; PF05645; RNA_pol_Rpc82; 1.
PE   3: Inferred from homology;
KW   DNA-directed RNA polymerase; Nucleus; Reference proteome; Transcription;
KW   Zinc.
FT   CHAIN           1..610
FT                   /note="DNA-directed RNA polymerase III subunit RPC3"
FT                   /id="PRO_0000351036"
FT   REGION          538..559
FT                   /note="Leucine-zipper"
SQ   SEQUENCE   610 AA;  69974 MW;  CD73BD30332BD6C9 CRC64;
     MDEDYYSAVR AQSPKTYLYA LTAETHLGEV ASVIITTLLA SGRLNIKQIS VKTKLAIKSI
     KSAIVSLIQL NCLYYWQDDK NPTIFYYSVN ETGLKTLVYS GDILNHITQE YGDEEAEIIQ
     NIIMNGHLKL DDYLRQYDND LEKSDEASLR LEKEKIFLKL YNEGWIKILS LNDFHHINDI
     WEKLFDDTLR NTPRSSTTSE VKRLAEAQSV CKEKLMALLE KTKQPLDLYI TENGYKKLNP
     NLVLTFNLTR FQKRSRTVAL TNLAKSRIGL ITSKVYEAAL KSVENGSPDL SHPFLEIPGL
     INNPTDVKDF KDSLETTLTA EKKIVFTVKD VMRYFPKLLD IKNSVITENS KRSFNDINAN
     PETSNKKIKL ENGNAFNTGG GASGANTSNS NNHLTASSFF TDEDRMSIIE QHLRLLAAGT
     NTQFVHEISP GRYAIPFVKL SNELKQFHYE SLVKSTLQDQ AFRVLRCIKH LKLADEKSIA
     NAVLLKEKTV RNEVYQLIKA NVVEIQEIPR SVDRAASKTF YLVKYKEYHR FESLINCLVY
     NMAEIVRNIQ NFKMENKILL DKCNRVDVEG NEDEMLLDSE LKTLHGLQNR EVMNLVRFNR
     TRSLWDIFTL