RPC3_PICST
ID RPC3_PICST Reviewed; 599 AA.
AC A3LQX9;
DT 23-SEP-2008, integrated into UniProtKB/Swiss-Prot.
DT 03-APR-2007, sequence version 1.
DT 03-AUG-2022, entry version 76.
DE RecName: Full=DNA-directed RNA polymerase III subunit RPC3;
DE Short=RNA polymerase III subunit C3;
GN Name=RPC82; Synonyms=RPC3; ORFNames=PICST_82840;
OS Scheffersomyces stipitis (strain ATCC 58785 / CBS 6054 / NBRC 10063 / NRRL
OS Y-11545) (Yeast) (Pichia stipitis).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC Saccharomycetales; Debaryomycetaceae; Scheffersomyces.
OX NCBI_TaxID=322104;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 58785 / CBS 6054 / NBRC 10063 / NRRL Y-11545;
RX PubMed=17334359; DOI=10.1038/nbt1290;
RA Jeffries T.W., Grigoriev I.V., Grimwood J., Laplaza J.M., Aerts A.,
RA Salamov A., Schmutz J., Lindquist E., Dehal P., Shapiro H., Jin Y.-S.,
RA Passoth V., Richardson P.M.;
RT "Genome sequence of the lignocellulose-bioconverting and xylose-fermenting
RT yeast Pichia stipitis.";
RL Nat. Biotechnol. 25:319-326(2007).
CC -!- FUNCTION: DNA-dependent RNA polymerase catalyzes the transcription of
CC DNA into RNA using the four ribonucleoside triphosphates as substrates.
CC Specific core component of RNA polymerase III which synthesizes small
CC RNAs, such as 5S rRNA and tRNAs (By similarity). {ECO:0000250}.
CC -!- SUBUNIT: Component of the RNA polymerase III (Pol III) complex
CC consisting of 17 subunits. {ECO:0000250}.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000250}.
CC -!- SIMILARITY: Belongs to the RNA polymerase beta chain family.
CC {ECO:0000305}.
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DR EMBL; CP000497; ABN65635.1; -; Genomic_DNA.
DR RefSeq; XP_001383664.1; XM_001383627.1.
DR AlphaFoldDB; A3LQX9; -.
DR SMR; A3LQX9; -.
DR STRING; 4924.XP_001383664.1; -.
DR EnsemblFungi; ABN65635; ABN65635; PICST_82840.
DR GeneID; 4837895; -.
DR KEGG; pic:PICST_82840; -.
DR eggNOG; KOG2587; Eukaryota.
DR HOGENOM; CLU_010734_0_0_1; -.
DR InParanoid; A3LQX9; -.
DR OMA; QLKMVNE; -.
DR OrthoDB; 809282at2759; -.
DR Proteomes; UP000002258; Chromosome 3.
DR GO; GO:0005666; C:RNA polymerase III complex; IEA:InterPro.
DR GO; GO:0003697; F:single-stranded DNA binding; IEA:InterPro.
DR GO; GO:0006351; P:transcription, DNA-templated; IEA:InterPro.
DR Gene3D; 1.10.10.10; -; 3.
DR InterPro; IPR013197; RNA_pol_III_RPC82-rel_HTH.
DR InterPro; IPR008806; RNA_pol_III_Rpc82_C.
DR InterPro; IPR039748; RPC3.
DR InterPro; IPR036388; WH-like_DNA-bd_sf.
DR PANTHER; PTHR12949; PTHR12949; 1.
DR Pfam; PF08221; HTH_9; 1.
DR Pfam; PF05645; RNA_pol_Rpc82; 1.
PE 3: Inferred from homology;
KW DNA-directed RNA polymerase; Nucleus; Reference proteome; Transcription;
KW Zinc.
FT CHAIN 1..599
FT /note="DNA-directed RNA polymerase III subunit RPC3"
FT /id="PRO_0000351040"
FT REGION 350..375
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 528..549
FT /note="Leucine-zipper"
FT COMPBIAS 352..375
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 599 AA; 68460 MW; 01A24A7BD508A2D8 CRC64;
MDIGDLPEAS KTQSPKSYLY TSIARNHLGD VAALIISCLI SYGRLTATDI SHRTKIPVKK
VKSALVSLIQ MNCIFYWRES GSKQVFYSFN ETGILVFLHS GDIISHVTTH YGEDSAEIVQ
NILVNGHIRI EDYVNNIDDE EKKLDIQTLF FRLFTDRWIV RLQPFNFNPV DDIWNQLYQE
TLKNTPRTST TSEVKRVAEA KEKTKTKFIN LIESGQSPKD LYLTQDGIKR LNPALVVTFN
LSRFQKHLRT TALVSLAKSR VGLLSARIYE SALKLVEASS PDLTHPFLQI SGLINDPEEA
RFFVNSIENK LVDEKKTVFN VRDLGRLLPH DLDLRNSILT YNFVKHNLTP KKRSASNGDD
ERPTKKIKTE DSDDIAESLE SNGTVQIESN GNGNSISLIQ HHLKLLSSGS GAQLLIEITP
GSYTVPYASL LKYLKQYNFE TLVKTTLGPN SFRILRCLKS LKIGDEKTIS NSVLLKEKTV
RNEIYKLLKA NMLEVQEVPR SADRAASKTF YLFRHKEFYS YEFLCNSLIF SMAEILSNIQ
AFREDHKILL EKCEREDVKG HEEELLLESE LKTLKSLQTR QVSNTVRFNR IKSLYEIYQ
