ID   RPC3_YARLI              Reviewed;         599 AA.
AC   Q6C2E2;
DT   23-SEP-2008, integrated into UniProtKB/Swiss-Prot.
DT   16-AUG-2004, sequence version 1.
DT   03-AUG-2022, entry version 86.
DE   RecName: Full=DNA-directed RNA polymerase III subunit RPC3;
DE            Short=RNA polymerase III subunit C3;
DE   AltName: Full=C82;
GN   Name=RPC82; Synonyms=RPC3; OrderedLocusNames=YALI0F08635g;
OS   Yarrowia lipolytica (strain CLIB 122 / E 150) (Yeast) (Candida lipolytica).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC   Saccharomycetales; Dipodascaceae; Yarrowia.
OX   NCBI_TaxID=284591;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=CLIB 122 / E 150;
RX   PubMed=15229592; DOI=10.1038/nature02579;
RA   Dujon B., Sherman D., Fischer G., Durrens P., Casaregola S., Lafontaine I.,
RA   de Montigny J., Marck C., Neuveglise C., Talla E., Goffard N., Frangeul L.,
RA   Aigle M., Anthouard V., Babour A., Barbe V., Barnay S., Blanchin S.,
RA   Beckerich J.-M., Beyne E., Bleykasten C., Boisrame A., Boyer J.,
RA   Cattolico L., Confanioleri F., de Daruvar A., Despons L., Fabre E.,
RA   Fairhead C., Ferry-Dumazet H., Groppi A., Hantraye F., Hennequin C.,
RA   Jauniaux N., Joyet P., Kachouri R., Kerrest A., Koszul R., Lemaire M.,
RA   Lesur I., Ma L., Muller H., Nicaud J.-M., Nikolski M., Oztas S.,
RA   Ozier-Kalogeropoulos O., Pellenz S., Potier S., Richard G.-F.,
RA   Straub M.-L., Suleau A., Swennen D., Tekaia F., Wesolowski-Louvel M.,
RA   Westhof E., Wirth B., Zeniou-Meyer M., Zivanovic Y., Bolotin-Fukuhara M.,
RA   Thierry A., Bouchier C., Caudron B., Scarpelli C., Gaillardin C.,
RA   Weissenbach J., Wincker P., Souciet J.-L.;
RT   "Genome evolution in yeasts.";
RL   Nature 430:35-44(2004).
CC   -!- FUNCTION: DNA-dependent RNA polymerase catalyzes the transcription of
CC       DNA into RNA using the four ribonucleoside triphosphates as substrates.
CC       Specific core component of RNA polymerase III which synthesizes small
CC       RNAs, such as 5S rRNA and tRNAs (By similarity). {ECO:0000250}.
CC   -!- SUBUNIT: Component of the RNA polymerase III (Pol III) complex
CC       consisting of 17 subunits. {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the RNA polymerase beta chain family.
CC       {ECO:0000305}.
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DR   EMBL; CR382132; CAG77977.1; -; Genomic_DNA.
DR   RefSeq; XP_505170.1; XM_505170.1.
DR   AlphaFoldDB; Q6C2E2; -.
DR   SMR; Q6C2E2; -.
DR   STRING; 4952.CAG77977; -.
DR   EnsemblFungi; CAG77977; CAG77977; YALI0_F08635g.
DR   GeneID; 2908482; -.
DR   KEGG; yli:YALI0F08635g; -.
DR   VEuPathDB; FungiDB:YALI0_F08635g; -.
DR   HOGENOM; CLU_023294_0_0_1; -.
DR   InParanoid; Q6C2E2; -.
DR   OMA; QLKMVNE; -.
DR   Proteomes; UP000001300; Chromosome F.
DR   GO; GO:0005666; C:RNA polymerase III complex; IBA:GO_Central.
DR   GO; GO:0003697; F:single-stranded DNA binding; IEA:InterPro.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:InterPro.
DR   Gene3D; 1.10.10.10; -; 3.
DR   InterPro; IPR013197; RNA_pol_III_RPC82-rel_HTH.
DR   InterPro; IPR008806; RNA_pol_III_Rpc82_C.
DR   InterPro; IPR039748; RPC3.
DR   InterPro; IPR036388; WH-like_DNA-bd_sf.
DR   PANTHER; PTHR12949; PTHR12949; 1.
DR   Pfam; PF08221; HTH_9; 1.
DR   Pfam; PF05645; RNA_pol_Rpc82; 1.
PE   3: Inferred from homology;
KW   DNA-directed RNA polymerase; Nucleus; Reference proteome; Transcription;
KW   Zinc.
FT   CHAIN           1..599
FT                   /note="DNA-directed RNA polymerase III subunit RPC3"
FT                   /id="PRO_0000351042"
FT   REGION          335..371
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          526..547
FT                   /note="Leucine-zipper"
FT   COMPBIAS        355..371
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   599 AA;  67329 MW;  A61A9BB849ADEC8B CRC64;
     MSELHNPDQS SRALFDLCRV LLKGIYGELS AVLVGSLLDY GRQTAAELAK TTKLPLSAVH
     SGLAALVQNR FVLYWANDRK SGRDTDDIGE SSSIHYVANW KEIYQVVRAG GMVDAVRKDF
     GKGPGGKSNP ESGERCAEIA QNLLVYGHMR VADYLEATPE HDRDSVEASI AVMLRKRFLV
     PVQAWQFKPE TDLYARMFRD HLSKLPLSMA ESARKNQAAV SAKTELERMQ EERNSLNLGF
     VSGSVARTKG VPVLNRAEKL DHQAVLCANP DKFLVIARNE ELAKLAEERC GKTAAEVYRQ
     CLSKYVGRLH SCTQDTSPGA EFNITSMEIA KTIDPRLDGL RPRGKGSRSV SPRPQSKRVK
     TEEGYTKTGD YDEKEVDVEE DMEEELSGVA LATAVSKQMQ ILAASPLKFV QSVGTKGGGE
     WYVNFKEATE CLRGARYEQI IQWKYGRVAK RLLRAVKDKG KVDEKLLTNI ALLPVKEILN
     HLHDLHSVGA LDVQELPRTA DRAASRTIFL WHHRANRAYS LISQDIYKSL SRCFERVAAE
     RAKLPILLSK LQREDVKGHE DEFLTEQEKA DLKGLRMREE KLLVQMNRLD GLIRVFRDY