ID   RPC6_DICDI              Reviewed;         293 AA.
AC   Q86JM3; Q55A81;
DT   08-APR-2008, integrated into UniProtKB/Swiss-Prot.
DT   01-JUN-2003, sequence version 1.
DT   25-MAY-2022, entry version 99.
DE   RecName: Full=DNA-directed RNA polymerase III subunit rpc6;
DE            Short=RNA polymerase III subunit C6;
DE   AltName: Full=DNA-directed RNA polymerase III subunit F;
GN   Name=polr3f; Synonyms=rpc34, rpc6; ORFNames=DDB_G0272022;
OS   Dictyostelium discoideum (Slime mold).
OC   Eukaryota; Amoebozoa; Evosea; Eumycetozoa; Dictyostelia; Dictyosteliales;
OC   Dictyosteliaceae; Dictyostelium.
OX   NCBI_TaxID=44689;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=AX4;
RX   PubMed=12097910; DOI=10.1038/nature00847;
RA   Gloeckner G., Eichinger L., Szafranski K., Pachebat J.A., Bankier A.T.,
RA   Dear P.H., Lehmann R., Baumgart C., Parra G., Abril J.F., Guigo R.,
RA   Kumpf K., Tunggal B., Cox E.C., Quail M.A., Platzer M., Rosenthal A.,
RA   Noegel A.A.;
RT   "Sequence and analysis of chromosome 2 of Dictyostelium discoideum.";
RL   Nature 418:79-85(2002).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=AX4;
RX   PubMed=15875012; DOI=10.1038/nature03481;
RA   Eichinger L., Pachebat J.A., Gloeckner G., Rajandream M.A., Sucgang R.,
RA   Berriman M., Song J., Olsen R., Szafranski K., Xu Q., Tunggal B.,
RA   Kummerfeld S., Madera M., Konfortov B.A., Rivero F., Bankier A.T.,
RA   Lehmann R., Hamlin N., Davies R., Gaudet P., Fey P., Pilcher K., Chen G.,
RA   Saunders D., Sodergren E.J., Davis P., Kerhornou A., Nie X., Hall N.,
RA   Anjard C., Hemphill L., Bason N., Farbrother P., Desany B., Just E.,
RA   Morio T., Rost R., Churcher C.M., Cooper J., Haydock S., van Driessche N.,
RA   Cronin A., Goodhead I., Muzny D.M., Mourier T., Pain A., Lu M., Harper D.,
RA   Lindsay R., Hauser H., James K.D., Quiles M., Madan Babu M., Saito T.,
RA   Buchrieser C., Wardroper A., Felder M., Thangavelu M., Johnson D.,
RA   Knights A., Loulseged H., Mungall K.L., Oliver K., Price C., Quail M.A.,
RA   Urushihara H., Hernandez J., Rabbinowitsch E., Steffen D., Sanders M.,
RA   Ma J., Kohara Y., Sharp S., Simmonds M.N., Spiegler S., Tivey A.,
RA   Sugano S., White B., Walker D., Woodward J.R., Winckler T., Tanaka Y.,
RA   Shaulsky G., Schleicher M., Weinstock G.M., Rosenthal A., Cox E.C.,
RA   Chisholm R.L., Gibbs R.A., Loomis W.F., Platzer M., Kay R.R.,
RA   Williams J.G., Dear P.H., Noegel A.A., Barrell B.G., Kuspa A.;
RT   "The genome of the social amoeba Dictyostelium discoideum.";
RL   Nature 435:43-57(2005).
CC   -!- FUNCTION: DNA-dependent RNA polymerase catalyzes the transcription of
CC       DNA into RNA using the four ribonucleoside triphosphates as substrates.
CC       Specific peripheric component of RNA polymerase III which synthesizes
CC       small RNAs, such as 5S rRNA and tRNAs. May direct RNA Pol III binding
CC       to the TFIIIB-DNA complex (By similarity). {ECO:0000250}.
CC   -!- SUBUNIT: Component of the RNA polymerase III (Pol III) complex.
CC       {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the eukaryotic RPC34/RPC39 RNA polymerase
CC       subunit family. {ECO:0000305}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; AAFI02000007; EAL71445.1; -; Genomic_DNA.
DR   RefSeq; XP_645385.1; XM_640293.1.
DR   AlphaFoldDB; Q86JM3; -.
DR   STRING; 44689.DDB0216315; -.
DR   PaxDb; Q86JM3; -.
DR   EnsemblProtists; EAL71445; EAL71445; DDB_G0272022.
DR   GeneID; 8618274; -.
DR   KEGG; ddi:DDB_G0272022; -.
DR   dictyBase; DDB_G0272022; rpc34.
DR   eggNOG; KOG3233; Eukaryota.
DR   HOGENOM; CLU_033661_1_0_1; -.
DR   InParanoid; Q86JM3; -.
DR   OMA; FSCDIFN; -.
DR   PhylomeDB; Q86JM3; -.
DR   Reactome; R-DDI-76061; RNA Polymerase III Transcription Initiation From Type 1 Promoter.
DR   Reactome; R-DDI-76066; RNA Polymerase III Transcription Initiation From Type 2 Promoter.
DR   PRO; PR:Q86JM3; -.
DR   Proteomes; UP000002195; Chromosome 2.
DR   GO; GO:0005666; C:RNA polymerase III complex; ISS:dictyBase.
DR   GO; GO:0003899; F:DNA-directed 5'-3' RNA polymerase activity; ISS:dictyBase.
DR   GO; GO:0006383; P:transcription by RNA polymerase III; ISS:dictyBase.
DR   Gene3D; 1.10.10.10; -; 2.
DR   InterPro; IPR007832; RNA_pol_Rpc34.
DR   InterPro; IPR016049; RNA_pol_Rpc34-like.
DR   InterPro; IPR036388; WH-like_DNA-bd_sf.
DR   InterPro; IPR036390; WH_DNA-bd_sf.
DR   PANTHER; PTHR12780; PTHR12780; 1.
DR   Pfam; PF05158; RNA_pol_Rpc34; 2.
DR   PIRSF; PIRSF028763; RNA_pol_Rpc34; 1.
DR   SUPFAM; SSF46785; SSF46785; 1.
PE   3: Inferred from homology;
KW   DNA-directed RNA polymerase; Nucleus; Reference proteome; Transcription.
FT   CHAIN           1..293
FT                   /note="DNA-directed RNA polymerase III subunit rpc6"
FT                   /id="PRO_0000328156"
SQ   SEQUENCE   293 AA;  33474 MW;  57F7FD77AE1626EF CRC64;
     MSEELENKFL DLCHKYPTGL TQQMIEVSLG HKMEEIVKVI NNLIKQGRLM LIQNSDETTS
     YKEVNPEDQA KFRGLGVEDF LIYQLIEASS NTGAWTRELK NSSGYQQVQI TKILKTLESR
     KLIKSVKSIQ SGRKKVYMLY NMEPSREITG GQLYSDQSYD HQYIQIMKMH IKTFVDNKGA
     VDLADIITYL RKVAEEATSQ SLGPEDIQAL VNTVIYDGDI EEMRDTRMGA MLGRRSGILY
     KPTKTPIPVN NFCNMPCGNC PVFDICSDNG LVSPKRCVYF KQYLEQDDES LDF