RPC6_SCHPO
ID RPC6_SCHPO Reviewed; 301 AA.
AC O94553; Q0QYE7;
DT 01-DEC-2000, integrated into UniProtKB/Swiss-Prot.
DT 01-MAY-1999, sequence version 1.
DT 25-MAY-2022, entry version 139.
DE RecName: Full=Probable DNA-directed RNA polymerase III subunit rpc6;
DE Short=RNA polymerase III subunit C6;
DE AltName: Full=DNA-directed RNA polymerase III 34 kDa polypeptide;
DE AltName: Full=RNA polymerase III subunit C34;
GN Name=rpc6; Synonyms=rpc34; ORFNames=SPCC290.02;
OS Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Taphrinomycotina;
OC Schizosaccharomycetes; Schizosaccharomycetales; Schizosaccharomycetaceae;
OC Schizosaccharomyces.
OX NCBI_TaxID=284812;
RN [1]
RP NUCLEOTIDE SEQUENCE [MRNA].
RC STRAIN=972 / ATCC 24843;
RX PubMed=16877568; DOI=10.1093/nar/gkl421;
RA Proshkina G.M., Shematorova E.K., Proshkin S.A., Zaros C., Thuriaux P.,
RA Shpakovski G.V.;
RT "Ancient origin, functional conservation and fast evolution of DNA-
RT dependent RNA polymerase III.";
RL Nucleic Acids Res. 34:3615-3624(2006).
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=972 / ATCC 24843;
RX PubMed=11859360; DOI=10.1038/nature724;
RA Wood V., Gwilliam R., Rajandream M.A., Lyne M.H., Lyne R., Stewart A.,
RA Sgouros J.G., Peat N., Hayles J., Baker S.G., Basham D., Bowman S.,
RA Brooks K., Brown D., Brown S., Chillingworth T., Churcher C.M., Collins M.,
RA Connor R., Cronin A., Davis P., Feltwell T., Fraser A., Gentles S.,
RA Goble A., Hamlin N., Harris D.E., Hidalgo J., Hodgson G., Holroyd S.,
RA Hornsby T., Howarth S., Huckle E.J., Hunt S., Jagels K., James K.D.,
RA Jones L., Jones M., Leather S., McDonald S., McLean J., Mooney P.,
RA Moule S., Mungall K.L., Murphy L.D., Niblett D., Odell C., Oliver K.,
RA O'Neil S., Pearson D., Quail M.A., Rabbinowitsch E., Rutherford K.M.,
RA Rutter S., Saunders D., Seeger K., Sharp S., Skelton J., Simmonds M.N.,
RA Squares R., Squares S., Stevens K., Taylor K., Taylor R.G., Tivey A.,
RA Walsh S.V., Warren T., Whitehead S., Woodward J.R., Volckaert G., Aert R.,
RA Robben J., Grymonprez B., Weltjens I., Vanstreels E., Rieger M.,
RA Schaefer M., Mueller-Auer S., Gabel C., Fuchs M., Duesterhoeft A.,
RA Fritzc C., Holzer E., Moestl D., Hilbert H., Borzym K., Langer I., Beck A.,
RA Lehrach H., Reinhardt R., Pohl T.M., Eger P., Zimmermann W., Wedler H.,
RA Wambutt R., Purnelle B., Goffeau A., Cadieu E., Dreano S., Gloux S.,
RA Lelaure V., Mottier S., Galibert F., Aves S.J., Xiang Z., Hunt C.,
RA Moore K., Hurst S.M., Lucas M., Rochet M., Gaillardin C., Tallada V.A.,
RA Garzon A., Thode G., Daga R.R., Cruzado L., Jimenez J., Sanchez M.,
RA del Rey F., Benito J., Dominguez A., Revuelta J.L., Moreno S.,
RA Armstrong J., Forsburg S.L., Cerutti L., Lowe T., McCombie W.R.,
RA Paulsen I., Potashkin J., Shpakovski G.V., Ussery D., Barrell B.G.,
RA Nurse P.;
RT "The genome sequence of Schizosaccharomyces pombe.";
RL Nature 415:871-880(2002).
CC -!- FUNCTION: DNA-dependent RNA polymerase catalyzes the transcription of
CC DNA into RNA using the four ribonucleoside triphosphates as substrates.
CC Specific peripheric component of RNA polymerase III which synthesizes
CC small RNAs, such as 5S rRNA and tRNAs.
CC -!- SUBUNIT: Component of the RNA polymerase III (Pol III) complex
CC consisting of 17 subunits (By similarity). Interacts with TFIIB.
CC {ECO:0000250}.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000250}.
CC -!- SIMILARITY: Belongs to the eukaryotic RPC34/RPC39 RNA polymerase
CC subunit family. {ECO:0000305}.
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DR EMBL; DQ156223; ABA54851.1; -; mRNA.
DR EMBL; CU329672; CAA22872.1; -; Genomic_DNA.
DR PIR; T41266; T41266.
DR RefSeq; NP_588398.1; NM_001023389.2.
DR AlphaFoldDB; O94553; -.
DR SMR; O94553; -.
DR BioGRID; 275566; 4.
DR STRING; 4896.SPCC290.02.1; -.
DR MaxQB; O94553; -.
DR PaxDb; O94553; -.
DR EnsemblFungi; SPCC290.02.1; SPCC290.02.1:pep; SPCC290.02.
DR GeneID; 2538992; -.
DR KEGG; spo:SPCC290.02; -.
DR PomBase; SPCC290.02; -.
DR VEuPathDB; FungiDB:SPCC290.02; -.
DR eggNOG; KOG3233; Eukaryota.
DR HOGENOM; CLU_033661_1_0_1; -.
DR InParanoid; O94553; -.
DR OMA; CEYMRDW; -.
DR PhylomeDB; O94553; -.
DR Reactome; R-SPO-76061; RNA Polymerase III Transcription Initiation From Type 1 Promoter.
DR Reactome; R-SPO-76066; RNA Polymerase III Transcription Initiation From Type 2 Promoter.
DR PRO; PR:O94553; -.
DR Proteomes; UP000002485; Chromosome III.
DR GO; GO:0005829; C:cytosol; HDA:PomBase.
DR GO; GO:0005634; C:nucleus; HDA:PomBase.
DR GO; GO:0005666; C:RNA polymerase III complex; ISO:PomBase.
DR GO; GO:0003899; F:DNA-directed 5'-3' RNA polymerase activity; ISO:PomBase.
DR GO; GO:0006383; P:transcription by RNA polymerase III; ISO:PomBase.
DR Gene3D; 1.10.10.10; -; 2.
DR InterPro; IPR007832; RNA_pol_Rpc34.
DR InterPro; IPR016049; RNA_pol_Rpc34-like.
DR InterPro; IPR036388; WH-like_DNA-bd_sf.
DR InterPro; IPR036390; WH_DNA-bd_sf.
DR PANTHER; PTHR12780; PTHR12780; 1.
DR Pfam; PF05158; RNA_pol_Rpc34; 1.
DR PIRSF; PIRSF028763; RNA_pol_Rpc34; 1.
DR SUPFAM; SSF46785; SSF46785; 2.
PE 2: Evidence at transcript level;
KW DNA-directed RNA polymerase; Nucleus; Reference proteome; Transcription.
FT CHAIN 1..301
FT /note="Probable DNA-directed RNA polymerase III subunit
FT rpc6"
FT /id="PRO_0000073976"
SQ SEQUENCE 301 AA; 33950 MW; 8DB7E152F7BFFD55 CRC64;
MADQLRTLPK NAKVIYEHCL KQIPNSLSQQ DLVEAIGASI SVNDLSSALN ILLSRRLLDP
LRQGNVLVYR AVRLDEAKTV STMEGDEQIV YSFIKNSGNE GIWRKTLTLR TNLHVSVVDR
CLKSLESKNL VKSIKSVKNP TRKIYMLYDL VPSTELTGGP WFTDQELDVE FIENLKKVIY
RYVHSKSFPP KKAAMGPDLV WGPEYNGYPT ALQIHNWLRS TNITKVDLSL ANVISLVDVL
IYDGKVEKRS DGASYRAIRV NNENIDAFTE SPCGNCPVSD ICDANSRVNP ITCEYLDKWL
N
