RPC7_SCHPO
ID RPC7_SCHPO Reviewed; 210 AA.
AC Q8WZJ8;
DT 04-NOV-2008, integrated into UniProtKB/Swiss-Prot.
DT 01-MAR-2002, sequence version 1.
DT 03-AUG-2022, entry version 110.
DE RecName: Full=DNA-directed RNA polymerase III subunit rpc31;
DE Short=RNA polymerase III subunit C31;
DE AltName: Full=DNA-directed RNA polymerase III 31 kDa polypeptide;
GN Name=rpc31; ORFNames=SPBC839.12;
OS Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Taphrinomycotina;
OC Schizosaccharomycetes; Schizosaccharomycetales; Schizosaccharomycetaceae;
OC Schizosaccharomyces.
OX NCBI_TaxID=284812;
RN [1]
RP NUCLEOTIDE SEQUENCE [MRNA], AND FUNCTION.
RC STRAIN=972 / ATCC 24843;
RX PubMed=16877568; DOI=10.1093/nar/gkl421;
RA Proshkina G.M., Shematorova E.K., Proshkin S.A., Zaros C., Thuriaux P.,
RA Shpakovski G.V.;
RT "Ancient origin, functional conservation and fast evolution of DNA-
RT dependent RNA polymerase III.";
RL Nucleic Acids Res. 34:3615-3624(2006).
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=972 / ATCC 24843;
RX PubMed=11859360; DOI=10.1038/nature724;
RA Wood V., Gwilliam R., Rajandream M.A., Lyne M.H., Lyne R., Stewart A.,
RA Sgouros J.G., Peat N., Hayles J., Baker S.G., Basham D., Bowman S.,
RA Brooks K., Brown D., Brown S., Chillingworth T., Churcher C.M., Collins M.,
RA Connor R., Cronin A., Davis P., Feltwell T., Fraser A., Gentles S.,
RA Goble A., Hamlin N., Harris D.E., Hidalgo J., Hodgson G., Holroyd S.,
RA Hornsby T., Howarth S., Huckle E.J., Hunt S., Jagels K., James K.D.,
RA Jones L., Jones M., Leather S., McDonald S., McLean J., Mooney P.,
RA Moule S., Mungall K.L., Murphy L.D., Niblett D., Odell C., Oliver K.,
RA O'Neil S., Pearson D., Quail M.A., Rabbinowitsch E., Rutherford K.M.,
RA Rutter S., Saunders D., Seeger K., Sharp S., Skelton J., Simmonds M.N.,
RA Squares R., Squares S., Stevens K., Taylor K., Taylor R.G., Tivey A.,
RA Walsh S.V., Warren T., Whitehead S., Woodward J.R., Volckaert G., Aert R.,
RA Robben J., Grymonprez B., Weltjens I., Vanstreels E., Rieger M.,
RA Schaefer M., Mueller-Auer S., Gabel C., Fuchs M., Duesterhoeft A.,
RA Fritzc C., Holzer E., Moestl D., Hilbert H., Borzym K., Langer I., Beck A.,
RA Lehrach H., Reinhardt R., Pohl T.M., Eger P., Zimmermann W., Wedler H.,
RA Wambutt R., Purnelle B., Goffeau A., Cadieu E., Dreano S., Gloux S.,
RA Lelaure V., Mottier S., Galibert F., Aves S.J., Xiang Z., Hunt C.,
RA Moore K., Hurst S.M., Lucas M., Rochet M., Gaillardin C., Tallada V.A.,
RA Garzon A., Thode G., Daga R.R., Cruzado L., Jimenez J., Sanchez M.,
RA del Rey F., Benito J., Dominguez A., Revuelta J.L., Moreno S.,
RA Armstrong J., Forsburg S.L., Cerutti L., Lowe T., McCombie W.R.,
RA Paulsen I., Potashkin J., Shpakovski G.V., Ussery D., Barrell B.G.,
RA Nurse P.;
RT "The genome sequence of Schizosaccharomyces pombe.";
RL Nature 415:871-880(2002).
RN [3]
RP SUBCELLULAR LOCATION [LARGE SCALE ANALYSIS].
RX PubMed=16823372; DOI=10.1038/nbt1222;
RA Matsuyama A., Arai R., Yashiroda Y., Shirai A., Kamata A., Sekido S.,
RA Kobayashi Y., Hashimoto A., Hamamoto M., Hiraoka Y., Horinouchi S.,
RA Yoshida M.;
RT "ORFeome cloning and global analysis of protein localization in the fission
RT yeast Schizosaccharomyces pombe.";
RL Nat. Biotechnol. 24:841-847(2006).
RN [4]
RP PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-103, AND IDENTIFICATION BY
RP MASS SPECTROMETRY.
RX PubMed=18257517; DOI=10.1021/pr7006335;
RA Wilson-Grady J.T., Villen J., Gygi S.P.;
RT "Phosphoproteome analysis of fission yeast.";
RL J. Proteome Res. 7:1088-1097(2008).
CC -!- FUNCTION: DNA-dependent RNA polymerase catalyzes the transcription of
CC DNA into RNA using the four ribonucleoside triphosphates as substrates.
CC Specific peripheric component of RNA polymerase III which synthesizes
CC small RNAs, such as 5S rRNA and tRNAs. {ECO:0000269|PubMed:16877568}.
CC -!- SUBUNIT: Component of the RNA polymerase III (Pol III) complex.
CC -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000269|PubMed:16823372}. Nucleus
CC {ECO:0000269|PubMed:16823372}.
CC -!- SIMILARITY: Belongs to the eukaryotic RPC7 RNA polymerase subunit
CC family. {ECO:0000305}.
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DR EMBL; DQ156222; ABA54850.1; -; mRNA.
DR EMBL; CU329671; CAB46705.1; -; Genomic_DNA.
DR PIR; T40719; T40719.
DR RefSeq; NP_595252.1; NM_001021158.2.
DR AlphaFoldDB; Q8WZJ8; -.
DR BioGRID; 277711; 7.
DR STRING; 4896.SPBC839.12.1; -.
DR iPTMnet; Q8WZJ8; -.
DR MaxQB; Q8WZJ8; -.
DR PaxDb; Q8WZJ8; -.
DR PRIDE; Q8WZJ8; -.
DR EnsemblFungi; SPBC839.12.1; SPBC839.12.1:pep; SPBC839.12.
DR GeneID; 2541197; -.
DR KEGG; spo:SPBC839.12; -.
DR PomBase; SPBC839.12; rpc31.
DR VEuPathDB; FungiDB:SPBC839.12; -.
DR eggNOG; ENOG502SEZJ; Eukaryota.
DR HOGENOM; CLU_1327066_0_0_1; -.
DR InParanoid; Q8WZJ8; -.
DR OMA; TFIDFTI; -.
DR PhylomeDB; Q8WZJ8; -.
DR Reactome; R-SPO-76061; RNA Polymerase III Transcription Initiation From Type 1 Promoter.
DR Reactome; R-SPO-76066; RNA Polymerase III Transcription Initiation From Type 2 Promoter.
DR PRO; PR:Q8WZJ8; -.
DR Proteomes; UP000002485; Chromosome II.
DR GO; GO:0005829; C:cytosol; HDA:PomBase.
DR GO; GO:0005634; C:nucleus; HDA:PomBase.
DR GO; GO:0005666; C:RNA polymerase III complex; ISO:PomBase.
DR GO; GO:0003899; F:DNA-directed 5'-3' RNA polymerase activity; ISO:PomBase.
DR GO; GO:0006383; P:transcription by RNA polymerase III; ISO:PomBase.
DR InterPro; IPR024661; RNA_pol_III_Rpc31.
DR PANTHER; PTHR15367; PTHR15367; 1.
DR Pfam; PF11705; RNA_pol_3_Rpc31; 1.
DR PIRSF; PIRSF000777; RNA_polIII_C31; 1.
PE 1: Evidence at protein level;
KW Cytoplasm; DNA-directed RNA polymerase; Nucleus; Phosphoprotein;
KW Reference proteome; Transcription.
FT CHAIN 1..210
FT /note="DNA-directed RNA polymerase III subunit rpc31"
FT /id="PRO_0000352832"
FT REGION 151..210
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 165..210
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT MOD_RES 103
FT /note="Phosphoserine"
FT /evidence="ECO:0000269|PubMed:18257517"
SQ SEQUENCE 210 AA; 24342 MW; A47CC3573168E60D CRC64;
MRRGARGSTN LGGMTWQEVL EFNANSTPTK LYPDRDIPLQ RSIRPEELLE LRFYKEIRTS
FLDESAFYIR RNPISVVQRN EDGLVRYSDR NKPKRKNDNL SLSDLDLDPK FFPEELRKTL
GAASATGRKR ARRKLDMKTF IDFTIKAQDL KDESSEAAHP NIEEEPDEGL EEEDEDFGDD
DDNDYGENYF DNGEGDDYDD YDGDEGAIYE
