ID   RPE5C_ARATH             Reviewed;         233 AA.
AC   Q9M1H8;
DT   18-SEP-2013, integrated into UniProtKB/Swiss-Prot.
DT   01-OCT-2000, sequence version 1.
DT   03-AUG-2022, entry version 120.
DE   RecName: Full=DNA-directed RNA polymerase V subunit 5C;
GN   Name=NRPE5C; Synonyms=NRPB5L2, RPB5E; OrderedLocusNames=At3g54490;
GN   ORFNames=T14E10.60;
OS   Arabidopsis thaliana (Mouse-ear cress).
OC   Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC   Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC   rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.
OX   NCBI_TaxID=3702;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=cv. Columbia;
RX   PubMed=11130713; DOI=10.1038/35048706;
RA   Salanoubat M., Lemcke K., Rieger M., Ansorge W., Unseld M., Fartmann B.,
RA   Valle G., Bloecker H., Perez-Alonso M., Obermaier B., Delseny M.,
RA   Boutry M., Grivell L.A., Mache R., Puigdomenech P., De Simone V.,
RA   Choisne N., Artiguenave F., Robert C., Brottier P., Wincker P.,
RA   Cattolico L., Weissenbach J., Saurin W., Quetier F., Schaefer M.,
RA   Mueller-Auer S., Gabel C., Fuchs M., Benes V., Wurmbach E., Drzonek H.,
RA   Erfle H., Jordan N., Bangert S., Wiedelmann R., Kranz H., Voss H.,
RA   Holland R., Brandt P., Nyakatura G., Vezzi A., D'Angelo M., Pallavicini A.,
RA   Toppo S., Simionati B., Conrad A., Hornischer K., Kauer G., Loehnert T.-H.,
RA   Nordsiek G., Reichelt J., Scharfe M., Schoen O., Bargues M., Terol J.,
RA   Climent J., Navarro P., Collado C., Perez-Perez A., Ottenwaelder B.,
RA   Duchemin D., Cooke R., Laudie M., Berger-Llauro C., Purnelle B., Masuy D.,
RA   de Haan M., Maarse A.C., Alcaraz J.-P., Cottet A., Casacuberta E.,
RA   Monfort A., Argiriou A., Flores M., Liguori R., Vitale D., Mannhaupt G.,
RA   Haase D., Schoof H., Rudd S., Zaccaria P., Mewes H.-W., Mayer K.F.X.,
RA   Kaul S., Town C.D., Koo H.L., Tallon L.J., Jenkins J., Rooney T., Rizzo M.,
RA   Walts A., Utterback T., Fujii C.Y., Shea T.P., Creasy T.H., Haas B.,
RA   Maiti R., Wu D., Peterson J., Van Aken S., Pai G., Militscher J.,
RA   Sellers P., Gill J.E., Feldblyum T.V., Preuss D., Lin X., Nierman W.C.,
RA   Salzberg S.L., White O., Venter J.C., Fraser C.M., Kaneko T., Nakamura Y.,
RA   Sato S., Kato T., Asamizu E., Sasamoto S., Kimura T., Idesawa K.,
RA   Kawashima K., Kishida Y., Kiyokawa C., Kohara M., Matsumoto M., Matsuno A.,
RA   Muraki A., Nakayama S., Nakazaki N., Shinpo S., Takeuchi C., Wada T.,
RA   Watanabe A., Yamada M., Yasuda M., Tabata S.;
RT   "Sequence and analysis of chromosome 3 of the plant Arabidopsis thaliana.";
RL   Nature 408:820-822(2000).
RN   [2]
RP   GENOME REANNOTATION.
RC   STRAIN=cv. Columbia;
RX   PubMed=27862469; DOI=10.1111/tpj.13415;
RA   Cheng C.Y., Krishnakumar V., Chan A.P., Thibaud-Nissen F., Schobel S.,
RA   Town C.D.;
RT   "Araport11: a complete reannotation of the Arabidopsis thaliana reference
RT   genome.";
RL   Plant J. 89:789-804(2017).
RN   [3]
RP   NOMENCLATURE.
RX   PubMed=19110459; DOI=10.1016/j.molcel.2008.12.015;
RA   Ream T.S., Haag J.R., Wierzbicki A.T., Nicora C.D., Norbeck A.D., Zhu J.K.,
RA   Hagen G., Guilfoyle T.J., Pasa-Tolic L., Pikaard C.S.;
RT   "Subunit compositions of the RNA-silencing enzymes Pol IV and Pol V reveal
RT   their origins as specialized forms of RNA polymerase II.";
RL   Mol. Cell 33:192-203(2009).
RN   [4]
RP   IDENTIFICATION, TISSUE SPECIFICITY, AND NOMENCLATURE.
RX   PubMed=19141635; DOI=10.1073/pnas.0810310106;
RA   Lahmy S., Pontier D., Cavel E., Vega D., El-Shami M., Kanno T.,
RA   Lagrange T.;
RT   "PolV(PolIVb) function in RNA-directed DNA methylation requires the
RT   conserved active site and an additional plant-specific subunit.";
RL   Proc. Natl. Acad. Sci. U.S.A. 106:941-946(2009).
CC   -!- FUNCTION: DNA-dependent RNA polymerase catalyzes the transcription of
CC       DNA into RNA using the four ribonucleoside triphosphates as substrates.
CC       Component of RNA polymerase V involved in RNA-directed DNA methylation-
CC       dependent (RdDM) silencing of endogenous repeated sequences, including
CC       transposable elements.
CC   -!- SUBUNIT: Component of the RNA polymerase V complex.
CC   -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000250}.
CC   -!- TISSUE SPECIFICITY: Expressed in flower buds and siliques.
CC       {ECO:0000269|PubMed:19141635}.
CC   -!- SIMILARITY: Belongs to the archaeal Rpo5/eukaryotic RPB5 RNA polymerase
CC       subunit family. {ECO:0000305}.
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DR   EMBL; AL138656; CAB77569.1; -; Genomic_DNA.
DR   EMBL; CP002686; AEE79238.1; -; Genomic_DNA.
DR   PIR; T47608; T47608.
DR   RefSeq; NP_191013.1; NM_115306.5.
DR   AlphaFoldDB; Q9M1H8; -.
DR   SMR; Q9M1H8; -.
DR   BioGRID; 9930; 1.
DR   STRING; 3702.AT3G54490.1; -.
DR   PaxDb; Q9M1H8; -.
DR   PRIDE; Q9M1H8; -.
DR   ProteomicsDB; 228219; -.
DR   EnsemblPlants; AT3G54490.1; AT3G54490.1; AT3G54490.
DR   GeneID; 824614; -.
DR   Gramene; AT3G54490.1; AT3G54490.1; AT3G54490.
DR   KEGG; ath:AT3G54490; -.
DR   Araport; AT3G54490; -.
DR   TAIR; locus:2096971; AT3G54490.
DR   eggNOG; KOG3218; Eukaryota.
DR   HOGENOM; CLU_058320_0_0_1; -.
DR   InParanoid; Q9M1H8; -.
DR   OMA; EIRKQTM; -.
DR   OrthoDB; 1255823at2759; -.
DR   PhylomeDB; Q9M1H8; -.
DR   PRO; PR:Q9M1H8; -.
DR   Proteomes; UP000006548; Chromosome 3.
DR   ExpressionAtlas; Q9M1H8; baseline and differential.
DR   Genevisible; Q9M1H8; AT.
DR   GO; GO:0000419; C:RNA polymerase V complex; IDA:UniProtKB.
DR   GO; GO:0003677; F:DNA binding; IEA:InterPro.
DR   GO; GO:0003899; F:DNA-directed 5'-3' RNA polymerase activity; IEA:InterPro.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:InterPro.
DR   Gene3D; 3.40.1340.10; -; 1.
DR   Gene3D; 3.90.940.20; -; 1.
DR   InterPro; IPR014381; Arch_Rpo5/euc_Rpb5.
DR   InterPro; IPR005571; RNA_pol_Rpb5_N.
DR   InterPro; IPR036710; RNA_pol_Rpb5_N_sf.
DR   InterPro; IPR000783; RNA_pol_subH/Rpb5_C.
DR   InterPro; IPR035913; RPB5-like_sf.
DR   PANTHER; PTHR10535; PTHR10535; 1.
DR   Pfam; PF01191; RNA_pol_Rpb5_C; 1.
DR   Pfam; PF03871; RNA_pol_Rpb5_N; 1.
DR   PIRSF; PIRSF000747; RPB5; 1.
DR   SUPFAM; SSF53036; SSF53036; 1.
DR   SUPFAM; SSF55287; SSF55287; 1.
PE   2: Evidence at transcript level;
KW   Nucleus; Reference proteome.
FT   CHAIN           1..233
FT                   /note="DNA-directed RNA polymerase V subunit 5C"
FT                   /id="PRO_0000423329"
SQ   SEQUENCE   233 AA;  26886 MW;  C72E507A229DD7AE CRC64;
     MEETMAEEGC CENVESTFDD GTNCISKTED TGGIESKRFY LARTTAFEML RDRGYEVNEA
     ELSLTLSEFR SVFGEKPELE RLRICVPLRS DPKKKILVVF MGTEPITVKS VRALHIQISN
     NVGLHAMILV LQSKMNHFAQ KALTTFPFTV ETFPIEDLLV NITKHIQQPK IEILNKEEKE
     QLLRKHALED KQLPYLQEKD SFVRYYGLKK KQVVKITYSK EPVGDFVTYR CII