ID   RPF1_XENLA              Reviewed;         343 AA.
AC   Q8AVP1;
DT   19-JUL-2005, integrated into UniProtKB/Swiss-Prot.
DT   01-MAR-2003, sequence version 1.
DT   03-AUG-2022, entry version 65.
DE   RecName: Full=Ribosome production factor 1;
DE   AltName: Full=Brix domain-containing protein 5;
DE   AltName: Full=Ribosome biogenesis protein RPF1;
GN   Name=rpf1; Synonyms=bxdc5;
OS   Xenopus laevis (African clawed frog).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia;
OC   Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Xenopus.
OX   NCBI_TaxID=8355;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   TISSUE=Embryo;
RG   NIH - Xenopus Gene Collection (XGC) project;
RL   Submitted (DEC-2002) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: May be required for ribosome biogenesis. {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Nucleus, nucleolus {ECO:0000250}.
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DR   EMBL; BC041557; AAH41557.1; -; mRNA.
DR   RefSeq; NP_001080272.1; NM_001086803.1.
DR   AlphaFoldDB; Q8AVP1; -.
DR   SMR; Q8AVP1; -.
DR   DNASU; 379964; -.
DR   GeneID; 379964; -.
DR   KEGG; xla:379964; -.
DR   CTD; 379964; -.
DR   OrthoDB; 768872at2759; -.
DR   Proteomes; UP000186698; Chromosome 4S.
DR   Bgee; 379964; Expressed in neurula embryo and 19 other tissues.
DR   GO; GO:0005730; C:nucleolus; ISS:UniProtKB.
DR   GO; GO:0003723; F:RNA binding; ISS:UniProtKB.
DR   GO; GO:0042134; F:rRNA primary transcript binding; IEA:InterPro.
DR   GO; GO:0006364; P:rRNA processing; IEA:UniProtKB-KW.
DR   InterPro; IPR007109; Brix.
DR   InterPro; IPR044281; IMP4/RPF1.
DR   PANTHER; PTHR22734; PTHR22734; 1.
DR   Pfam; PF04427; Brix; 1.
DR   SMART; SM00879; Brix; 1.
DR   PROSITE; PS50833; BRIX; 1.
PE   2: Evidence at transcript level;
KW   Nucleus; Reference proteome; Ribosome biogenesis; RNA-binding;
KW   rRNA processing; rRNA-binding.
FT   CHAIN           1..343
FT                   /note="Ribosome production factor 1"
FT                   /id="PRO_0000120253"
FT   DOMAIN          136..319
FT                   /note="Brix"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00034"
FT   REGION          1..51
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          77..97
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          297..314
FT                   /note="RNA-binding"
FT                   /evidence="ECO:0000250"
FT   COMPBIAS        1..27
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   343 AA;  40208 MW;  C2CFEA3F6E26F7DC CRC64;
     MAEKKGPEAK KQKKMKNKSK VEETDAGEEA GASEEQQQVT RLPPAFSLSE IKNKQRRQFM
     FIKLKQEKRK EKLILRKKRK KEREALGDKA PPKPVPKTIE NQRVYDETTV DPADEEVALD
     EATDEFAPYF NKQTTPKILI TTSDRPRGRS VRFTEQLSSI IPNSDVYYRR GLALKKIIPQ
     CVSRDYTDLL VINEDRKVPN GLVLCHLPDG PTAHFKISNV RLRKEMKRKG KEPTEHKPEV
     ILNNFTTRLG HSIGRMFASL YPHDPHFVGR QVATFHNQRD YIFFRYHRYL FKSEKKVGIQ
     ELGPRFTLKL RSLQKGTFDS KYGEYEWVHK RHEMDTSRRK FHL