RPF2_ARATH
ID RPF2_ARATH Reviewed; 314 AA.
AC Q9LUG5; Q8LCK0;
DT 26-SEP-2001, integrated into UniProtKB/Swiss-Prot.
DT 01-OCT-2000, sequence version 1.
DT 25-MAY-2022, entry version 120.
DE RecName: Full=Ribosome production factor 2 homolog;
DE AltName: Full=Brix domain-containing protein 1 homolog;
DE AltName: Full=Ribosome biogenesis protein RPF2 homolog;
GN OrderedLocusNames=At3g23620; ORFNames=MDB19.11;
OS Arabidopsis thaliana (Mouse-ear cress).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.
OX NCBI_TaxID=3702;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Columbia;
RX PubMed=10819329; DOI=10.1093/dnares/7.2.131;
RA Sato S., Nakamura Y., Kaneko T., Katoh T., Asamizu E., Tabata S.;
RT "Structural analysis of Arabidopsis thaliana chromosome 3. I. Sequence
RT features of the regions of 4,504,864 bp covered by sixty P1 and TAC
RT clones.";
RL DNA Res. 7:131-135(2000).
RN [2]
RP GENOME REANNOTATION.
RC STRAIN=cv. Columbia;
RX PubMed=27862469; DOI=10.1111/tpj.13415;
RA Cheng C.Y., Krishnakumar V., Chan A.P., Thibaud-Nissen F., Schobel S.,
RA Town C.D.;
RT "Araport11: a complete reannotation of the Arabidopsis thaliana reference
RT genome.";
RL Plant J. 89:789-804(2017).
RN [3]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC STRAIN=cv. Columbia;
RX PubMed=14593172; DOI=10.1126/science.1088305;
RA Yamada K., Lim J., Dale J.M., Chen H., Shinn P., Palm C.J., Southwick A.M.,
RA Wu H.C., Kim C.J., Nguyen M., Pham P.K., Cheuk R.F., Karlin-Newmann G.,
RA Liu S.X., Lam B., Sakano H., Wu T., Yu G., Miranda M., Quach H.L.,
RA Tripp M., Chang C.H., Lee J.M., Toriumi M.J., Chan M.M., Tang C.C.,
RA Onodera C.S., Deng J.M., Akiyama K., Ansari Y., Arakawa T., Banh J.,
RA Banno F., Bowser L., Brooks S.Y., Carninci P., Chao Q., Choy N., Enju A.,
RA Goldsmith A.D., Gurjal M., Hansen N.F., Hayashizaki Y., Johnson-Hopson C.,
RA Hsuan V.W., Iida K., Karnes M., Khan S., Koesema E., Ishida J., Jiang P.X.,
RA Jones T., Kawai J., Kamiya A., Meyers C., Nakajima M., Narusaka M.,
RA Seki M., Sakurai T., Satou M., Tamse R., Vaysberg M., Wallender E.K.,
RA Wong C., Yamamura Y., Yuan S., Shinozaki K., Davis R.W., Theologis A.,
RA Ecker J.R.;
RT "Empirical analysis of transcriptional activity in the Arabidopsis
RT genome.";
RL Science 302:842-846(2003).
RN [4]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RA Brover V.V., Troukhan M.E., Alexandrov N.A., Lu Y.-P., Flavell R.B.,
RA Feldmann K.A.;
RT "Full-length cDNA from Arabidopsis thaliana.";
RL Submitted (MAR-2002) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Nucleus, nucleolus {ECO:0000250}.
CC -!- SIMILARITY: Belongs to the RPF2 family. {ECO:0000305}.
CC -!- SEQUENCE CAUTION:
CC Sequence=AAM63614.1; Type=Erroneous initiation; Evidence={ECO:0000305};
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DR EMBL; AB023036; BAB02781.1; -; Genomic_DNA.
DR EMBL; CP002686; AEE76787.1; -; Genomic_DNA.
DR EMBL; AY070410; AAL49906.1; -; mRNA.
DR EMBL; AY122939; AAM67472.1; -; mRNA.
DR EMBL; AY086550; AAM63614.1; ALT_INIT; mRNA.
DR RefSeq; NP_566734.1; NM_113266.4.
DR AlphaFoldDB; Q9LUG5; -.
DR SMR; Q9LUG5; -.
DR BioGRID; 7274; 38.
DR IntAct; Q9LUG5; 3.
DR STRING; 3702.AT3G23620.1; -.
DR PaxDb; Q9LUG5; -.
DR PRIDE; Q9LUG5; -.
DR ProteomicsDB; 228232; -.
DR EnsemblPlants; AT3G23620.1; AT3G23620.1; AT3G23620.
DR GeneID; 821942; -.
DR Gramene; AT3G23620.1; AT3G23620.1; AT3G23620.
DR KEGG; ath:AT3G23620; -.
DR Araport; AT3G23620; -.
DR TAIR; locus:2088015; AT3G23620.
DR eggNOG; KOG3031; Eukaryota.
DR HOGENOM; CLU_049783_1_0_1; -.
DR InParanoid; Q9LUG5; -.
DR OMA; GCKIPRI; -.
DR OrthoDB; 974865at2759; -.
DR PhylomeDB; Q9LUG5; -.
DR PRO; PR:Q9LUG5; -.
DR Proteomes; UP000006548; Chromosome 3.
DR ExpressionAtlas; Q9LUG5; baseline and differential.
DR Genevisible; Q9LUG5; AT.
DR GO; GO:0005730; C:nucleolus; IDA:TAIR.
DR GO; GO:0019843; F:rRNA binding; IDA:TAIR.
DR GO; GO:0000463; P:maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA); IBA:GO_Central.
DR GO; GO:0000027; P:ribosomal large subunit assembly; IBA:GO_Central.
DR GO; GO:0032774; P:RNA biosynthetic process; IMP:TAIR.
DR InterPro; IPR007109; Brix.
DR InterPro; IPR039770; Rpf2.
DR PANTHER; PTHR12728; PTHR12728; 1.
DR Pfam; PF04427; Brix; 1.
DR SMART; SM00879; Brix; 1.
DR PROSITE; PS50833; BRIX; 1.
PE 2: Evidence at transcript level;
KW Nucleus; Reference proteome.
FT CHAIN 1..314
FT /note="Ribosome production factor 2 homolog"
FT /id="PRO_0000120227"
FT DOMAIN 28..238
FT /note="Brix"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00034"
FT REGION 238..314
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 238..262
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 272..314
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT CONFLICT 133
FT /note="D -> Y (in Ref. 4; AAM63614)"
FT /evidence="ECO:0000305"
FT CONFLICT 222
FT /note="G -> S (in Ref. 4; AAM63614)"
FT /evidence="ECO:0000305"
SQ SEQUENCE 314 AA; 35728 MW; F7543B58411A109A CRC64;
MMEIRTPKTG KAKRVLESRA PKLVETGKKT LILHGTKTSA TLSSVMTELY RLKKGGAIRY
SRRNENIRPF ESGGETSLEF FSQKTDCSIF VYGSHTKKRP DNLVLGRMYD HQVYDLIEVG
IENFKSLRAF SYDKKFAPHE GTKPFICFIG EGFENVSELK HLKEVLTDLF RGEVVDNLNL
TGLDRAYVCS AISPTKVFLT HCALKLKKSG SIVPRMELVE VGPSMDLVIR RNRLPNDSLM
KEAMRTSKDK PKKKEKNVDQ DAVLGKTGKI YMPDQKLKEM KLFDKSKGSK RERKDAKLKH
KEETVAKKMK VSSE
