ID   RPF2_CAEEL              Reviewed;         297 AA.
AC   Q9N3F0;
DT   26-SEP-2001, integrated into UniProtKB/Swiss-Prot.
DT   01-OCT-2000, sequence version 1.
DT   03-AUG-2022, entry version 117.
DE   RecName: Full=Ribosome production factor 2 homolog;
DE   AltName: Full=Brix domain-containing protein 1 homolog;
DE   AltName: Full=Ribosome biogenesis protein RPF2 homolog;
GN   ORFNames=Y54E10A.10;
OS   Caenorhabditis elegans.
OC   Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC   Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae;
OC   Caenorhabditis.
OX   NCBI_TaxID=6239;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Bristol N2;
RX   PubMed=9851916; DOI=10.1126/science.282.5396.2012;
RG   The C. elegans sequencing consortium;
RT   "Genome sequence of the nematode C. elegans: a platform for investigating
RT   biology.";
RL   Science 282:2012-2018(1998).
CC   -!- SUBCELLULAR LOCATION: Nucleus, nucleolus {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the RPF2 family. {ECO:0000305}.
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DR   EMBL; FO081614; CCD72829.1; -; Genomic_DNA.
DR   RefSeq; NP_491117.1; NM_058716.5.
DR   AlphaFoldDB; Q9N3F0; -.
DR   SMR; Q9N3F0; -.
DR   BioGRID; 37369; 11.
DR   STRING; 6239.Y54E10A.10; -.
DR   EPD; Q9N3F0; -.
DR   PaxDb; Q9N3F0; -.
DR   PeptideAtlas; Q9N3F0; -.
DR   EnsemblMetazoa; Y54E10A.10.1; Y54E10A.10.1; WBGene00021830.
DR   GeneID; 171892; -.
DR   KEGG; cel:CELE_Y54E10A.10; -.
DR   UCSC; Y54E10A.10.1; c. elegans.
DR   CTD; 171892; -.
DR   WormBase; Y54E10A.10; CE24439; WBGene00021830; -.
DR   eggNOG; KOG3031; Eukaryota.
DR   GeneTree; ENSGT00390000007279; -.
DR   HOGENOM; CLU_049783_1_1_1; -.
DR   InParanoid; Q9N3F0; -.
DR   OMA; GCKIPRI; -.
DR   OrthoDB; 974865at2759; -.
DR   PhylomeDB; Q9N3F0; -.
DR   PRO; PR:Q9N3F0; -.
DR   Proteomes; UP000001940; Chromosome I.
DR   Bgee; WBGene00021830; Expressed in larva and 4 other tissues.
DR   GO; GO:0005730; C:nucleolus; IBA:GO_Central.
DR   GO; GO:0019843; F:rRNA binding; IBA:GO_Central.
DR   GO; GO:0000463; P:maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA); IBA:GO_Central.
DR   GO; GO:0000027; P:ribosomal large subunit assembly; IBA:GO_Central.
DR   InterPro; IPR007109; Brix.
DR   InterPro; IPR039770; Rpf2.
DR   PANTHER; PTHR12728; PTHR12728; 1.
DR   Pfam; PF04427; Brix; 1.
DR   SMART; SM00879; Brix; 1.
DR   PROSITE; PS50833; BRIX; 1.
PE   3: Inferred from homology;
KW   Nucleus; Reference proteome.
FT   CHAIN           1..297
FT                   /note="Ribosome production factor 2 homolog"
FT                   /id="PRO_0000120225"
FT   DOMAIN          28..232
FT                   /note="Brix"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00034"
SQ   SEQUENCE   297 AA;  33460 MW;  E315B220DCE6F4A5 CRC64;
     MVRVEKIKTK KGKRVLVNRA SKTVENDKKA LFCRGAKTNE IISHAMMDLF DMKKPLTTKM
     DKHNPYHLFE DETPIVRAGS KFDTSLFVLG SNSKKKPNCL TFGRTYDGQL LDMAELRITS
     YKSSSNFEAA KMTLGSKPCV ILEGAAFESD GDMKRIGNLM VDWFRGPKVD TVRLEGLETV
     IVFTALDETN LALRVYRPML KKSATATPRV ELAEMGPSIS FEVMRKKLAD DALFKLACKK
     PKALMKKRRK NLSEDVFGNQ LARVHVGKQR TDDIQTRKVK ALRKTPLVEA APENAIE