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RPF2_DICDI
ID   RPF2_DICDI              Reviewed;         307 AA.
AC   Q54DJ0;
DT   08-APR-2008, integrated into UniProtKB/Swiss-Prot.
DT   24-MAY-2005, sequence version 1.
DT   25-MAY-2022, entry version 80.
DE   RecName: Full=Ribosome production factor 2 homolog;
DE   AltName: Full=Brix domain-containing protein 1 homolog;
DE   AltName: Full=Ribosome biogenesis protein RPF2 homolog;
GN   Name=bxdc1; ORFNames=DDB_G0292216;
OS   Dictyostelium discoideum (Slime mold).
OC   Eukaryota; Amoebozoa; Evosea; Eumycetozoa; Dictyostelia; Dictyosteliales;
OC   Dictyosteliaceae; Dictyostelium.
OX   NCBI_TaxID=44689;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=AX4;
RX   PubMed=15875012; DOI=10.1038/nature03481;
RA   Eichinger L., Pachebat J.A., Gloeckner G., Rajandream M.A., Sucgang R.,
RA   Berriman M., Song J., Olsen R., Szafranski K., Xu Q., Tunggal B.,
RA   Kummerfeld S., Madera M., Konfortov B.A., Rivero F., Bankier A.T.,
RA   Lehmann R., Hamlin N., Davies R., Gaudet P., Fey P., Pilcher K., Chen G.,
RA   Saunders D., Sodergren E.J., Davis P., Kerhornou A., Nie X., Hall N.,
RA   Anjard C., Hemphill L., Bason N., Farbrother P., Desany B., Just E.,
RA   Morio T., Rost R., Churcher C.M., Cooper J., Haydock S., van Driessche N.,
RA   Cronin A., Goodhead I., Muzny D.M., Mourier T., Pain A., Lu M., Harper D.,
RA   Lindsay R., Hauser H., James K.D., Quiles M., Madan Babu M., Saito T.,
RA   Buchrieser C., Wardroper A., Felder M., Thangavelu M., Johnson D.,
RA   Knights A., Loulseged H., Mungall K.L., Oliver K., Price C., Quail M.A.,
RA   Urushihara H., Hernandez J., Rabbinowitsch E., Steffen D., Sanders M.,
RA   Ma J., Kohara Y., Sharp S., Simmonds M.N., Spiegler S., Tivey A.,
RA   Sugano S., White B., Walker D., Woodward J.R., Winckler T., Tanaka Y.,
RA   Shaulsky G., Schleicher M., Weinstock G.M., Rosenthal A., Cox E.C.,
RA   Chisholm R.L., Gibbs R.A., Loomis W.F., Platzer M., Kay R.R.,
RA   Williams J.G., Dear P.H., Noegel A.A., Barrell B.G., Kuspa A.;
RT   "The genome of the social amoeba Dictyostelium discoideum.";
RL   Nature 435:43-57(2005).
CC   -!- SUBCELLULAR LOCATION: Nucleus, nucleolus {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the RPF2 family. {ECO:0000305}.
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DR   EMBL; AAFI02000188; EAL61318.1; -; Genomic_DNA.
DR   RefSeq; XP_629737.1; XM_629735.1.
DR   AlphaFoldDB; Q54DJ0; -.
DR   SMR; Q54DJ0; -.
DR   STRING; 44689.DDB0238377; -.
DR   PaxDb; Q54DJ0; -.
DR   EnsemblProtists; EAL61318; EAL61318; DDB_G0292216.
DR   GeneID; 8628566; -.
DR   KEGG; ddi:DDB_G0292216; -.
DR   dictyBase; DDB_G0292216; bxdc1.
DR   eggNOG; KOG3031; Eukaryota.
DR   HOGENOM; CLU_049783_1_1_1; -.
DR   InParanoid; Q54DJ0; -.
DR   OMA; GCKIPRI; -.
DR   PhylomeDB; Q54DJ0; -.
DR   PRO; PR:Q54DJ0; -.
DR   Proteomes; UP000002195; Chromosome 6.
DR   GO; GO:0005730; C:nucleolus; ISS:dictyBase.
DR   GO; GO:0019843; F:rRNA binding; ISS:dictyBase.
DR   GO; GO:0000463; P:maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA); IBA:GO_Central.
DR   GO; GO:0000027; P:ribosomal large subunit assembly; ISS:dictyBase.
DR   InterPro; IPR007109; Brix.
DR   InterPro; IPR039770; Rpf2.
DR   PANTHER; PTHR12728; PTHR12728; 1.
DR   Pfam; PF04427; Brix; 1.
DR   SMART; SM00879; Brix; 1.
DR   PROSITE; PS50833; BRIX; 1.
PE   3: Inferred from homology;
KW   Nucleus; Reference proteome.
FT   CHAIN           1..307
FT                   /note="Ribosome production factor 2 homolog"
FT                   /id="PRO_0000328307"
FT   DOMAIN          36..239
FT                   /note="Brix"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00034"
SQ   SEQUENCE   307 AA;  34831 MW;  9A65A562BA49DC0C CRC64;
     MSSKPKKIFL KREPSKSHAA KKFLRNKEAK EVEIVKQAMF IRGQQSSDII QKLQKDLFML
     KKPEAIQYNK KNAFRPMESA ESIEFLGEKS NSSLFTFGSH SKKREHNLIM GRLFDNAVFD
     MIEMGISNFK SIKEFGADGS AVGNKPMFIF QGNEFENNET VKKVGNLFLD MFRGRLVEYI
     NLVGLDHVVI MTAVDDKILF RHYTTIFSPS GSKIPKVDLK EVGPSFDITI RRTKLASADL
     EKEAYKVHKS VVPKAKKNVE TDALGQTFGT VYKNHQDFNK IAFRKNRALR GKNPVPTLNQ
     AATSVDV
 
 
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