AB2F_ARATH
ID AB2F_ARATH Reviewed; 678 AA.
AC Q9FIB4;
DT 07-JUL-2009, integrated into UniProtKB/Swiss-Prot.
DT 07-JUL-2009, sequence version 2.
DT 03-AUG-2022, entry version 121.
DE RecName: Full=ABC transporter F family member 2;
DE Short=ABC transporter ABCF.2;
DE Short=AtABCF2;
DE AltName: Full=GCN20-type ATP-binding cassette protein GCN2;
GN Name=ABCF2; Synonyms=GCN2; OrderedLocusNames=At5g09930; ORFNames=MYH9.14;
OS Arabidopsis thaliana (Mouse-ear cress).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.
OX NCBI_TaxID=3702;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Columbia;
RX PubMed=10048488; DOI=10.1093/dnares/5.6.379;
RA Asamizu E., Sato S., Kaneko T., Nakamura Y., Kotani H., Miyajima N.,
RA Tabata S.;
RT "Structural analysis of Arabidopsis thaliana chromosome 5. VIII. Sequence
RT features of the regions of 1,081,958 bp covered by seventeen physically
RT assigned P1 and TAC clones.";
RL DNA Res. 5:379-391(1998).
RN [2]
RP GENOME REANNOTATION.
RC STRAIN=cv. Columbia;
RX PubMed=27862469; DOI=10.1111/tpj.13415;
RA Cheng C.Y., Krishnakumar V., Chan A.P., Thibaud-Nissen F., Schobel S.,
RA Town C.D.;
RT "Araport11: a complete reannotation of the Arabidopsis thaliana reference
RT genome.";
RL Plant J. 89:789-804(2017).
RN [3]
RP GENE FAMILY, AND NOMENCLATURE.
RX PubMed=11346655; DOI=10.1074/jbc.m103104200;
RA Sanchez-Fernandez R., Davies T.G., Coleman J.O., Rea P.A.;
RT "The Arabidopsis thaliana ABC protein superfamily, a complete inventory.";
RL J. Biol. Chem. 276:30231-30244(2001).
RN [4]
RP GENE FAMILY.
RX PubMed=11855639; DOI=10.1007/s004250100661;
RA Martinoia E., Klein M., Geisler M., Bovet L., Forestier C.,
RA Kolukisaoglu H.U., Mueller-Roeber B., Schulz B.;
RT "Multifunctionality of plant ABC transporters -- more than just
RT detoxifiers.";
RL Planta 214:345-355(2002).
RN [5]
RP GENE FAMILY, AND NOMENCLATURE.
RX PubMed=18299247; DOI=10.1016/j.tplants.2008.02.001;
RA Verrier P.J., Bird D., Burla B., Dassa E., Forestier C., Geisler M.,
RA Klein M., Kolukisaoglu H.U., Lee Y., Martinoia E., Murphy A., Rea P.A.,
RA Samuels L., Schulz B., Spalding E.J., Yazaki K., Theodoulou F.L.;
RT "Plant ABC proteins - a unified nomenclature and updated inventory.";
RL Trends Plant Sci. 13:151-159(2008).
CC -!- SIMILARITY: Belongs to the ABC transporter superfamily. ABCF family.
CC EF3 (TC 3.A.1.121) subfamily. {ECO:0000305}.
CC -!- SEQUENCE CAUTION:
CC Sequence=BAB09414.1; Type=Erroneous gene model prediction; Evidence={ECO:0000305};
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; AB016893; BAB09414.1; ALT_SEQ; Genomic_DNA.
DR EMBL; CP002688; AED91468.1; -; Genomic_DNA.
DR RefSeq; NP_196555.2; NM_121030.3.
DR AlphaFoldDB; Q9FIB4; -.
DR SMR; Q9FIB4; -.
DR STRING; 3702.AT5G09930.1; -.
DR iPTMnet; Q9FIB4; -.
DR PaxDb; Q9FIB4; -.
DR PRIDE; Q9FIB4; -.
DR ProteomicsDB; 244626; -.
DR EnsemblPlants; AT5G09930.1; AT5G09930.1; AT5G09930.
DR GeneID; 830854; -.
DR Gramene; AT5G09930.1; AT5G09930.1; AT5G09930.
DR KEGG; ath:AT5G09930; -.
DR Araport; AT5G09930; -.
DR TAIR; locus:2178168; AT5G09930.
DR eggNOG; KOG0927; Eukaryota.
DR HOGENOM; CLU_000604_36_0_1; -.
DR InParanoid; Q9FIB4; -.
DR OMA; IASEIAW; -.
DR OrthoDB; 580544at2759; -.
DR PhylomeDB; Q9FIB4; -.
DR PRO; PR:Q9FIB4; -.
DR Proteomes; UP000006548; Chromosome 5.
DR ExpressionAtlas; Q9FIB4; baseline and differential.
DR Genevisible; Q9FIB4; AT.
DR GO; GO:0005524; F:ATP binding; IBA:GO_Central.
DR GO; GO:0003729; F:mRNA binding; IDA:TAIR.
DR Gene3D; 3.40.50.300; -; 2.
DR InterPro; IPR003593; AAA+_ATPase.
DR InterPro; IPR032781; ABC_tran_Xtn.
DR InterPro; IPR003439; ABC_transporter-like_ATP-bd.
DR InterPro; IPR017871; ABC_transporter-like_CS.
DR InterPro; IPR027417; P-loop_NTPase.
DR Pfam; PF00005; ABC_tran; 2.
DR Pfam; PF12848; ABC_tran_Xtn; 1.
DR SMART; SM00382; AAA; 2.
DR SUPFAM; SSF52540; SSF52540; 2.
DR PROSITE; PS00211; ABC_TRANSPORTER_1; 2.
DR PROSITE; PS50893; ABC_TRANSPORTER_2; 2.
PE 3: Inferred from homology;
KW ATP-binding; Nucleotide-binding; Reference proteome; Repeat; Transport.
FT CHAIN 1..678
FT /note="ABC transporter F family member 2"
FT /id="PRO_0000379140"
FT DOMAIN 84..342
FT /note="ABC transporter 1"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00434"
FT DOMAIN 411..626
FT /note="ABC transporter 2"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00434"
FT REGION 630..678
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 630..658
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 659..678
FT /note="Basic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT BINDING 116..123
FT /ligand="ATP"
FT /ligand_id="ChEBI:CHEBI:30616"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00434"
FT BINDING 443..450
FT /ligand="ATP"
FT /ligand_id="ChEBI:CHEBI:30616"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00434"
SQ SEQUENCE 678 AA; 76491 MW; BAB1D77CCE143AA8 CRC64;
MVLTTNLYSL NLRSTFFFTN TITCPTLFTF KLSSVSNPRR VFPNIRAHVS AASSNSELES
LLSTDRKLIS KQSNNGASSI SSGVRLENIS KSYEGITVLK DVTWEVKKGE KVGLIGVNGA
GKTTQLRIIT GQEEPDSGNV IWAKPNLKVA FLSQEFEVSM GKTVKEEFMC TFKEEMEIAR
KLENLQKAIE EAVDDLELMG KLLDEFDLLQ RRAQEVDLDS IHAKISKLMS ELGFVSEDAD
RLVASFSSGW QMRMSLGKIL LQNPDLLLLD EPTNHLDLDT IEWLEGYLIK QDVPMVIISH
DRAFLDQLCT KIVETEMGVS RTFDGNYSQY VISKAELVEA QYAAWEKQQK EIEATKDLIS
RLSAGANSGR ASSAEKKLEK LQEEELIEKP FQRKQMKIRF PECGLSGRSV VTVKNLVFGF
DDKMLFNKAN LAIERGEKVA IIGPNGCGKS TLLKLIMGLE KPMRGEVILG EHNVLPNYFE
QNQAEAQDLD KTVIETVVEA AVDWRIDDIK ALLGRCNFKA DMLDRKVSLL SGGEKARLAF
CKFMVKPSTL LVLDEPTNHL DIPSKEMLEE AINEYKGTVI TVSHDRYFIK QIVNRVIEVR
DGGLMDYAGD YNYFLEKNVE ARARELEREA ELEEKAPKVK AKSKMSKAER EARKKQKMKA
FQASKKKSKS SKNAKRWN