ID   RPIA_BOVIN              Reviewed;         264 AA.
AC   Q3T186;
DT   01-MAY-2007, integrated into UniProtKB/Swiss-Prot.
DT   24-JUL-2007, sequence version 2.
DT   03-AUG-2022, entry version 88.
DE   RecName: Full=Ribose-5-phosphate isomerase;
DE            EC=5.3.1.6;
DE   AltName: Full=Phosphoriboisomerase;
DE   Flags: Fragment;
GN   Name=RPIA;
OS   Bos taurus (Bovine).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae;
OC   Bovinae; Bos.
OX   NCBI_TaxID=9913;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   STRAIN=Crossbred X Angus; TISSUE=Ileum;
RG   NIH - Mammalian Gene Collection (MGC) project;
RL   Submitted (AUG-2005) to the EMBL/GenBank/DDBJ databases.
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=aldehydo-D-ribose 5-phosphate = D-ribulose 5-phosphate;
CC         Xref=Rhea:RHEA:14657, ChEBI:CHEBI:58121, ChEBI:CHEBI:58273;
CC         EC=5.3.1.6;
CC   -!- PATHWAY: Carbohydrate degradation; pentose phosphate pathway; D-ribose
CC       5-phosphate from D-ribulose 5-phosphate (non-oxidative stage): step
CC       1/1.
CC   -!- SIMILARITY: Belongs to the ribose 5-phosphate isomerase family.
CC       {ECO:0000305}.
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DR   EMBL; BC102070; AAI02071.2; -; mRNA.
DR   RefSeq; NP_001030510.2; NM_001035433.2.
DR   AlphaFoldDB; Q3T186; -.
DR   SMR; Q3T186; -.
DR   STRING; 9913.ENSBTAP00000003719; -.
DR   PaxDb; Q3T186; -.
DR   PRIDE; Q3T186; -.
DR   GeneID; 613376; -.
DR   KEGG; bta:613376; -.
DR   CTD; 22934; -.
DR   eggNOG; KOG3075; Eukaryota.
DR   HOGENOM; CLU_056590_0_2_1; -.
DR   InParanoid; Q3T186; -.
DR   OrthoDB; 1074761at2759; -.
DR   UniPathway; UPA00115; UER00412.
DR   Proteomes; UP000009136; Unplaced.
DR   GO; GO:0043231; C:intracellular membrane-bounded organelle; IBA:GO_Central.
DR   GO; GO:0004751; F:ribose-5-phosphate isomerase activity; IBA:GO_Central.
DR   GO; GO:0006014; P:D-ribose metabolic process; IBA:GO_Central.
DR   GO; GO:0009052; P:pentose-phosphate shunt, non-oxidative branch; IBA:GO_Central.
DR   CDD; cd01398; RPI_A; 1.
DR   HAMAP; MF_00170; Rib_5P_isom_A; 1.
DR   InterPro; IPR037171; NagB/RpiA_transferase-like.
DR   InterPro; IPR020672; Ribose5P_isomerase_typA_subgr.
DR   InterPro; IPR004788; Ribose5P_isomerase_type_A.
DR   PANTHER; PTHR11934; PTHR11934; 1.
DR   Pfam; PF06026; Rib_5-P_isom_A; 1.
DR   SUPFAM; SSF100950; SSF100950; 1.
DR   TIGRFAMs; TIGR00021; rpiA; 1.
PE   2: Evidence at transcript level;
KW   Isomerase; Phosphoprotein; Reference proteome.
FT   CHAIN           <1..264
FT                   /note="Ribose-5-phosphate isomerase"
FT                   /id="PRO_0000284953"
FT   REGION          1..20
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   MOD_RES         60
FT                   /note="Phosphoserine"
FT                   /evidence="ECO:0000250|UniProtKB:P49247"
FT   NON_TER         1
SQ   SEQUENCE   264 AA;  28753 MW;  C940FDCCD985646D CRC64;
     LPGRSQFGAG STSTGVRETN IVCPGPSAMS KAEEAKKLAG RAAVENHVRN NQVLGIGSGS
     TIVHAVQRIA ERVEQENLKL VCIPTSFQAR QLILQYGLTL SDLDRHPEID LAIDGADEVD
     ADLNLIKGGG GCLTQEKIVA GNASRFIVIA DFRKDSKNLG DQWHKGIPIE VIPMAYVPVS
     RTVTQKFGGV IELRMAVNKA GPVVTDNGNF ILDWKFDRVH KWSEVNIAIK MIPGVVDTGL
     FINMAERVYF GMQDGSVNMR EKPF