RPKL_ARATH
ID RPKL_ARATH Reviewed; 757 AA.
AC Q94C77; O49483;
DT 30-MAY-2006, integrated into UniProtKB/Swiss-Prot.
DT 01-DEC-2001, sequence version 1.
DT 25-MAY-2022, entry version 126.
DE RecName: Full=Receptor protein kinase-like protein At4g34220;
DE Flags: Precursor;
GN OrderedLocusNames=At4g34220; ORFNames=F10M10.12, F28A23_20;
OS Arabidopsis thaliana (Mouse-ear cress).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.
OX NCBI_TaxID=3702;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Columbia;
RX PubMed=10617198; DOI=10.1038/47134;
RA Mayer K.F.X., Schueller C., Wambutt R., Murphy G., Volckaert G., Pohl T.,
RA Duesterhoeft A., Stiekema W., Entian K.-D., Terryn N., Harris B.,
RA Ansorge W., Brandt P., Grivell L.A., Rieger M., Weichselgartner M.,
RA de Simone V., Obermaier B., Mache R., Mueller M., Kreis M., Delseny M.,
RA Puigdomenech P., Watson M., Schmidtheini T., Reichert B., Portetelle D.,
RA Perez-Alonso M., Boutry M., Bancroft I., Vos P., Hoheisel J.,
RA Zimmermann W., Wedler H., Ridley P., Langham S.-A., McCullagh B.,
RA Bilham L., Robben J., van der Schueren J., Grymonprez B., Chuang Y.-J.,
RA Vandenbussche F., Braeken M., Weltjens I., Voet M., Bastiaens I., Aert R.,
RA Defoor E., Weitzenegger T., Bothe G., Ramsperger U., Hilbert H., Braun M.,
RA Holzer E., Brandt A., Peters S., van Staveren M., Dirkse W., Mooijman P.,
RA Klein Lankhorst R., Rose M., Hauf J., Koetter P., Berneiser S., Hempel S.,
RA Feldpausch M., Lamberth S., Van den Daele H., De Keyser A., Buysshaert C.,
RA Gielen J., Villarroel R., De Clercq R., van Montagu M., Rogers J.,
RA Cronin A., Quail M.A., Bray-Allen S., Clark L., Doggett J., Hall S.,
RA Kay M., Lennard N., McLay K., Mayes R., Pettett A., Rajandream M.A.,
RA Lyne M., Benes V., Rechmann S., Borkova D., Bloecker H., Scharfe M.,
RA Grimm M., Loehnert T.-H., Dose S., de Haan M., Maarse A.C., Schaefer M.,
RA Mueller-Auer S., Gabel C., Fuchs M., Fartmann B., Granderath K., Dauner D.,
RA Herzl A., Neumann S., Argiriou A., Vitale D., Liguori R., Piravandi E.,
RA Massenet O., Quigley F., Clabauld G., Muendlein A., Felber R., Schnabl S.,
RA Hiller R., Schmidt W., Lecharny A., Aubourg S., Chefdor F., Cooke R.,
RA Berger C., Monfort A., Casacuberta E., Gibbons T., Weber N., Vandenbol M.,
RA Bargues M., Terol J., Torres A., Perez-Perez A., Purnelle B., Bent E.,
RA Johnson S., Tacon D., Jesse T., Heijnen L., Schwarz S., Scholler P.,
RA Heber S., Francs P., Bielke C., Frishman D., Haase D., Lemcke K.,
RA Mewes H.-W., Stocker S., Zaccaria P., Bevan M., Wilson R.K.,
RA de la Bastide M., Habermann K., Parnell L., Dedhia N., Gnoj L., Schutz K.,
RA Huang E., Spiegel L., Sekhon M., Murray J., Sheet P., Cordes M.,
RA Abu-Threideh J., Stoneking T., Kalicki J., Graves T., Harmon G.,
RA Edwards J., Latreille P., Courtney L., Cloud J., Abbott A., Scott K.,
RA Johnson D., Minx P., Bentley D., Fulton B., Miller N., Greco T., Kemp K.,
RA Kramer J., Fulton L., Mardis E., Dante M., Pepin K., Hillier L.W.,
RA Nelson J., Spieth J., Ryan E., Andrews S., Geisel C., Layman D., Du H.,
RA Ali J., Berghoff A., Jones K., Drone K., Cotton M., Joshu C., Antonoiu B.,
RA Zidanic M., Strong C., Sun H., Lamar B., Yordan C., Ma P., Zhong J.,
RA Preston R., Vil D., Shekher M., Matero A., Shah R., Swaby I.K.,
RA O'Shaughnessy A., Rodriguez M., Hoffman J., Till S., Granat S., Shohdy N.,
RA Hasegawa A., Hameed A., Lodhi M., Johnson A., Chen E., Marra M.A.,
RA Martienssen R., McCombie W.R.;
RT "Sequence and analysis of chromosome 4 of the plant Arabidopsis thaliana.";
RL Nature 402:769-777(1999).
RN [2]
RP GENOME REANNOTATION.
RC STRAIN=cv. Columbia;
RX PubMed=27862469; DOI=10.1111/tpj.13415;
RA Cheng C.Y., Krishnakumar V., Chan A.P., Thibaud-Nissen F., Schobel S.,
RA Town C.D.;
RT "Araport11: a complete reannotation of the Arabidopsis thaliana reference
RT genome.";
RL Plant J. 89:789-804(2017).
RN [3]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC STRAIN=cv. Columbia;
RX PubMed=14593172; DOI=10.1126/science.1088305;
RA Yamada K., Lim J., Dale J.M., Chen H., Shinn P., Palm C.J., Southwick A.M.,
RA Wu H.C., Kim C.J., Nguyen M., Pham P.K., Cheuk R.F., Karlin-Newmann G.,
RA Liu S.X., Lam B., Sakano H., Wu T., Yu G., Miranda M., Quach H.L.,
RA Tripp M., Chang C.H., Lee J.M., Toriumi M.J., Chan M.M., Tang C.C.,
RA Onodera C.S., Deng J.M., Akiyama K., Ansari Y., Arakawa T., Banh J.,
RA Banno F., Bowser L., Brooks S.Y., Carninci P., Chao Q., Choy N., Enju A.,
RA Goldsmith A.D., Gurjal M., Hansen N.F., Hayashizaki Y., Johnson-Hopson C.,
RA Hsuan V.W., Iida K., Karnes M., Khan S., Koesema E., Ishida J., Jiang P.X.,
RA Jones T., Kawai J., Kamiya A., Meyers C., Nakajima M., Narusaka M.,
RA Seki M., Sakurai T., Satou M., Tamse R., Vaysberg M., Wallender E.K.,
RA Wong C., Yamamura Y., Yuan S., Shinozaki K., Davis R.W., Theologis A.,
RA Ecker J.R.;
RT "Empirical analysis of transcriptional activity in the Arabidopsis
RT genome.";
RL Science 302:842-846(2003).
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000305}; Single-pass membrane
CC protein {ECO:0000305}.
CC -!- DOMAIN: The protein kinase domain is predicted to be catalytically
CC inactive.
CC -!- SIMILARITY: Belongs to the protein kinase superfamily. {ECO:0000305}.
CC -!- SEQUENCE CAUTION:
CC Sequence=CAA17550.1; Type=Erroneous gene model prediction; Note=The predicted gene At4g34220 has been split into 2 genes: At4g34215 and At4g34220.; Evidence={ECO:0000305};
CC Sequence=CAB80139.1; Type=Erroneous gene model prediction; Note=The predicted gene At4g34220 has been split into 2 genes: At4g34215 and At4g34220.; Evidence={ECO:0000305};
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DR EMBL; AL021961; CAA17550.1; ALT_SEQ; Genomic_DNA.
DR EMBL; AL161585; CAB80139.1; ALT_SEQ; Genomic_DNA.
DR EMBL; CP002687; AEE86343.1; -; Genomic_DNA.
DR EMBL; AY035109; AAK59614.1; -; mRNA.
DR EMBL; AY113903; AAM44951.1; -; mRNA.
DR PIR; T05414; T05414.
DR RefSeq; NP_567961.1; NM_119586.3.
DR AlphaFoldDB; Q94C77; -.
DR SMR; Q94C77; -.
DR BioGRID; 14853; 44.
DR IntAct; Q94C77; 43.
DR STRING; 3702.AT4G34220.1; -.
DR iPTMnet; Q94C77; -.
DR PaxDb; Q94C77; -.
DR PRIDE; Q94C77; -.
DR ProteomicsDB; 227960; -.
DR EnsemblPlants; AT4G34220.1; AT4G34220.1; AT4G34220.
DR GeneID; 829571; -.
DR Gramene; AT4G34220.1; AT4G34220.1; AT4G34220.
DR KEGG; ath:AT4G34220; -.
DR Araport; AT4G34220; -.
DR TAIR; locus:2124296; AT4G34220.
DR eggNOG; ENOG502QRF8; Eukaryota.
DR HOGENOM; CLU_000288_92_6_1; -.
DR InParanoid; Q94C77; -.
DR OMA; PYQPPEW; -.
DR OrthoDB; 486781at2759; -.
DR PhylomeDB; Q94C77; -.
DR PRO; PR:Q94C77; -.
DR Proteomes; UP000006548; Chromosome 4.
DR ExpressionAtlas; Q94C77; baseline and differential.
DR Genevisible; Q94C77; AT.
DR GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR GO; GO:0005886; C:plasma membrane; IDA:TAIR.
DR GO; GO:0005524; F:ATP binding; IEA:InterPro.
DR GO; GO:0042631; P:cellular response to water deprivation; IMP:TAIR.
DR GO; GO:0009789; P:positive regulation of abscisic acid-activated signaling pathway; IMP:TAIR.
DR GO; GO:0010030; P:positive regulation of seed germination; IMP:TAIR.
DR GO; GO:0006468; P:protein phosphorylation; IEA:InterPro.
DR Gene3D; 3.80.10.10; -; 2.
DR InterPro; IPR011009; Kinase-like_dom_sf.
DR InterPro; IPR032675; LRR_dom_sf.
DR InterPro; IPR013210; LRR_N_plant-typ.
DR InterPro; IPR000719; Prot_kinase_dom.
DR Pfam; PF08263; LRRNT_2; 1.
DR Pfam; PF00069; Pkinase; 1.
DR SUPFAM; SSF56112; SSF56112; 1.
DR PROSITE; PS50011; PROTEIN_KINASE_DOM; 1.
PE 2: Evidence at transcript level;
KW Leucine-rich repeat; Membrane; Phosphoprotein; Reference proteome; Repeat;
KW Signal; Transmembrane; Transmembrane helix.
FT SIGNAL 1..26
FT /evidence="ECO:0000255"
FT CHAIN 27..757
FT /note="Receptor protein kinase-like protein At4g34220"
FT /id="PRO_0000239081"
FT TRANSMEM 339..359
FT /note="Helical"
FT /evidence="ECO:0000255"
FT REPEAT 104..126
FT /note="LRR 1"
FT REPEAT 128..150
FT /note="LRR 2"
FT REPEAT 152..174
FT /note="LRR 3"
FT REPEAT 176..198
FT /note="LRR 4"
FT REPEAT 199..219
FT /note="LRR 5"
FT REPEAT 220..242
FT /note="LRR 6"
FT REPEAT 245..267
FT /note="LRR 7"
FT DOMAIN 471..753
FT /note="Protein kinase"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00159"
FT REGION 633..654
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 635..654
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT MOD_RES 473
FT /note="Phosphoserine"
FT /evidence="ECO:0000250|UniProtKB:Q94F62"
FT MOD_RES 494
FT /note="Phosphothreonine"
FT /evidence="ECO:0000250|UniProtKB:Q94F62"
FT MOD_RES 553
FT /note="Phosphoserine"
FT /evidence="ECO:0000250|UniProtKB:Q94AG2"
FT MOD_RES 638
FT /note="Phosphothreonine"
FT /evidence="ECO:0000250|UniProtKB:Q94F62"
FT MOD_RES 639
FT /note="Phosphothreonine"
FT /evidence="ECO:0000250|UniProtKB:Q94F62"
SQ SEQUENCE 757 AA; 82602 MW; FEBA93BB487B6FED CRC64;
MTSNRSNLLF SLVLFHFLFV PTQLQALNTD GVLLLTFKYS ILTDPLSVLR NWNYDDATPC
LWTGVTCTEL GKPNTPDMFR VTSLVLPNKH LLGSITPDLF SIPYLRILDL SSNFFNGSLP
DSVFNATELQ SISLGSNNLS GDLPKSVNSV TNLQLLNLSA NAFTGEIPLN ISLLKNLTVV
SLSKNTFSGD IPSGFEAAQI LDLSSNLLNG SLPKDLGGKS LHYLNLSHNK VLGEISPNFA
EKFPANATVD LSFNNLTGPI PSSLSLLNQK AESFSGNQEL CGKPLKILCS IPSTLSNPPN
ISETTSPAIA VKPRSTAPIN PLTEKPNQTG KSKLKPSTIA AITVADIVGL AFIGLLVLYV
YQVRKRRRYP ESSKFSFFKF CLEKNEAKKS KPSTTEVTVP ESPEAKTTCG SCIILTGGRY
DETSTSESDV ENQQTVQAFT RTDGGQLKQS SQTQLVTVDG ETRLDLDTLL KASAYILGTT
GTGIVYKAVL ENGTAFAVRR IETESCAAAK PKEFEREVRA IAKLRHPNLV RIRGFCWGDD
EKLLISDYVP NGSLLCFFTA TKASSSSSSS SSLQNPLTFE ARLKIARGMA RGLSYINEKK
QVHGNIKPNN ILLNAENEPI ITDLGLDRLM TPARESHTTG PTSSSPYQPP EWSTSLKPNP
KWDVYSFGVI LLELLTSKVF SVDHDIDQFS NLSDSAAEEN GRFLRLIDGA IRSDVARHED
AAMACFRLGI ECVSSLPQKR PSMKELVQVL EKICVLV
