RPN1_CHICK
ID RPN1_CHICK Reviewed; 28 AA.
AC P80896;
DT 01-NOV-1997, integrated into UniProtKB/Swiss-Prot.
DT 01-NOV-1997, sequence version 1.
DT 25-MAY-2022, entry version 76.
DE RecName: Full=Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 1 {ECO:0000250|UniProtKB:P04843};
DE AltName: Full=Dolichyl-diphosphooligosaccharide--protein glycosyltransferase 65 kDa subunit;
DE AltName: Full=Oligosaccharyl transferase 65-I kDa subunit;
DE AltName: Full=Ribophorin I;
DE Short=RPN-I;
DE AltName: Full=Ribophorin-1;
DE Flags: Fragments;
GN Name=RPN1 {ECO:0000250|UniProtKB:P04843};
OS Gallus gallus (Chicken).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda;
OC Coelurosauria; Aves; Neognathae; Galloanserae; Galliformes; Phasianidae;
OC Phasianinae; Gallus.
OX NCBI_TaxID=9031;
RN [1]
RP PROTEIN SEQUENCE.
RC TISSUE=Oviduct;
RX PubMed=8175777; DOI=10.1016/s0021-9258(17)36853-9;
RA Kumar V., Heinemann F.S., Ozols J.;
RT "Purification and characterization of avian oligosaccharyltransferase.
RT Complete amino acid sequence of the 50-kDa subunit.";
RL J. Biol. Chem. 269:13451-13457(1994).
CC -!- FUNCTION: Subunit of the oligosaccharyl transferase (OST) complex that
CC catalyzes the initial transfer of a defined glycan
CC (Glc(3)Man(9)GlcNAc(2) in eukaryotes) from the lipid carrier dolichol-
CC pyrophosphate to an asparagine residue within an Asn-X-Ser/Thr
CC consensus motif in nascent polypeptide chains, the first step in
CC protein N-glycosylation. N-glycosylation occurs cotranslationally and
CC the complex associates with the Sec61 complex at the channel-forming
CC translocon complex that mediates protein translocation across the
CC endoplasmic reticulum (ER). All subunits are required for a maximal
CC enzyme activity. {ECO:0000250|UniProtKB:P41543}.
CC -!- PATHWAY: Protein modification; protein glycosylation.
CC {ECO:0000250|UniProtKB:P04843}.
CC -!- SUBUNIT: Component of the oligosaccharyltransferase (OST) complex.
CC {ECO:0000250|UniProtKB:E2RQ08}.
CC -!- SUBCELLULAR LOCATION: Endoplasmic reticulum membrane {ECO:0000250};
CC Single-pass type I membrane protein {ECO:0000250}.
CC -!- SIMILARITY: Belongs to the OST1 family. {ECO:0000305}.
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DR PIR; B54127; B54127.
DR UniPathway; UPA00378; -.
DR Proteomes; UP000000539; Unplaced.
DR GO; GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR GO; GO:0006486; P:protein glycosylation; IEA:UniProtKB-UniPathway.
PE 1: Evidence at protein level;
KW Direct protein sequencing; Endoplasmic reticulum; Membrane;
KW Reference proteome; Transmembrane.
FT CHAIN <1..>28
FT /note="Dolichyl-diphosphooligosaccharide--protein
FT glycosyltransferase subunit 1"
FT /id="PRO_0000058091"
FT NON_CONS 10..11
FT /evidence="ECO:0000305"
FT NON_TER 1
FT NON_TER 28
SQ SEQUENCE 28 AA; 3349 MW; 5FAC15F4F4FD335A CRC64;
VFTHVLQPYP EIRPRFPLVG GWKTHYXV
