ID   RPN2_CHICK              Reviewed;          36 AA.
AC   P80897;
DT   01-NOV-1997, integrated into UniProtKB/Swiss-Prot.
DT   01-NOV-1997, sequence version 1.
DT   25-MAY-2022, entry version 71.
DE   RecName: Full=Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 2 {ECO:0000250|UniProtKB:P04844};
DE   AltName: Full=Dolichyl-diphosphooligosaccharide--protein glycosyltransferase 65-II kDa subunit;
DE   AltName: Full=Ribophorin II;
DE            Short=RPN-II;
DE   AltName: Full=Ribophorin-2;
DE   Flags: Fragments;
GN   Name=RPN2 {ECO:0000250|UniProtKB:P04844};
OS   Gallus gallus (Chicken).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda;
OC   Coelurosauria; Aves; Neognathae; Galloanserae; Galliformes; Phasianidae;
OC   Phasianinae; Gallus.
OX   NCBI_TaxID=9031;
RN   [1]
RP   PROTEIN SEQUENCE.
RC   TISSUE=Oviduct;
RX   PubMed=8175777; DOI=10.1016/s0021-9258(17)36853-9;
RA   Kumar V., Heinemann F.S., Ozols J.;
RT   "Purification and characterization of avian oligosaccharyltransferase.
RT   Complete amino acid sequence of the 50-kDa subunit.";
RL   J. Biol. Chem. 269:13451-13457(1994).
CC   -!- FUNCTION: Subunit of the oligosaccharyl transferase (OST) complex that
CC       catalyzes the initial transfer of a defined glycan
CC       (Glc(3)Man(9)GlcNAc(2) in eukaryotes) from the lipid carrier dolichol-
CC       pyrophosphate to an asparagine residue within an Asn-X-Ser/Thr
CC       consensus motif in nascent polypeptide chains, the first step in
CC       protein N-glycosylation. N-glycosylation occurs cotranslationally and
CC       the complex associates with the Sec61 complex at the channel-forming
CC       translocon complex that mediates protein translocation across the
CC       endoplasmic reticulum (ER). All subunits are required for a maximal
CC       enzyme activity. {ECO:0000250|UniProtKB:F1PCT7}.
CC   -!- PATHWAY: Protein modification; protein glycosylation.
CC       {ECO:0000250|UniProtKB:P04844}.
CC   -!- SUBUNIT: Component of the oligosaccharyltransferase (OST) complex.
CC       {ECO:0000250|UniProtKB:F1PCT7}.
CC   -!- SUBCELLULAR LOCATION: Endoplasmic reticulum
CC       {ECO:0000250|UniProtKB:F1PCT7}. Endoplasmic reticulum membrane; Multi-
CC       pass membrane protein {ECO:0000305}.
CC   -!- SIMILARITY: Belongs to the SWP1 family. {ECO:0000305}.
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DR   PIR; C54127; C54127.
DR   AlphaFoldDB; P80897; -.
DR   SMR; P80897; -.
DR   eggNOG; KOG2447; Eukaryota.
DR   UniPathway; UPA00378; -.
DR   Proteomes; UP000000539; Unplaced.
DR   GO; GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0006486; P:protein glycosylation; IEA:UniProtKB-UniPathway.
PE   1: Evidence at protein level;
KW   Direct protein sequencing; Endoplasmic reticulum; Membrane;
KW   Reference proteome; Transmembrane.
FT   CHAIN           <1..>36
FT                   /note="Dolichyl-diphosphooligosaccharide--protein
FT                   glycosyltransferase subunit 2"
FT                   /id="PRO_0000058092"
FT   NON_CONS        18..19
FT                   /evidence="ECO:0000305"
FT   NON_TER         1
FT   NON_TER         36
SQ   SEQUENCE   36 AA;  3927 MW;  2A8D47456E6C132E CRC64;
     NAIFSKKNFE TLSEAFSVFQ TLKYLAILGG VTFLAG