RPND_ECO57
ID RPND_ECO57 Reviewed; 260 AA.
AC P58245;
DT 29-AUG-2001, integrated into UniProtKB/Swiss-Prot.
DT 29-AUG-2001, sequence version 1.
DT 03-AUG-2022, entry version 90.
DE RecName: Full=Recombination-promoting nuclease RpnD {ECO:0000250|UniProtKB:P39387};
DE EC=3.1.21.-;
GN Name=rpnD; Synonyms=yjiP; OrderedLocusNames=Z5940, ECs5301;
OS Escherichia coli O157:H7.
OC Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC Enterobacteriaceae; Escherichia.
OX NCBI_TaxID=83334;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=O157:H7 / EDL933 / ATCC 700927 / EHEC;
RX PubMed=11206551; DOI=10.1038/35054089;
RA Perna N.T., Plunkett G. III, Burland V., Mau B., Glasner J.D., Rose D.J.,
RA Mayhew G.F., Evans P.S., Gregor J., Kirkpatrick H.A., Posfai G.,
RA Hackett J., Klink S., Boutin A., Shao Y., Miller L., Grotbeck E.J.,
RA Davis N.W., Lim A., Dimalanta E.T., Potamousis K., Apodaca J.,
RA Anantharaman T.S., Lin J., Yen G., Schwartz D.C., Welch R.A.,
RA Blattner F.R.;
RT "Genome sequence of enterohaemorrhagic Escherichia coli O157:H7.";
RL Nature 409:529-533(2001).
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=O157:H7 / Sakai / RIMD 0509952 / EHEC;
RX PubMed=11258796; DOI=10.1093/dnares/8.1.11;
RA Hayashi T., Makino K., Ohnishi M., Kurokawa K., Ishii K., Yokoyama K.,
RA Han C.-G., Ohtsubo E., Nakayama K., Murata T., Tanaka M., Tobe T., Iida T.,
RA Takami H., Honda T., Sasakawa C., Ogasawara N., Yasunaga T., Kuhara S.,
RA Shiba T., Hattori M., Shinagawa H.;
RT "Complete genome sequence of enterohemorrhagic Escherichia coli O157:H7 and
RT genomic comparison with a laboratory strain K-12.";
RL DNA Res. 8:11-22(2001).
CC -!- FUNCTION: A low activity DNA endonuclease probably yielding 3'-hydroxyl
CC ends. Involved in RecA-independent recombination and horizontal gene
CC transfer (By similarity). {ECO:0000250|UniProtKB:P39387}.
CC -!- SIMILARITY: Belongs to the Rpn/YhgA-like nuclease family.
CC {ECO:0000305}.
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DR EMBL; AE005174; AAG59523.1; -; Genomic_DNA.
DR EMBL; BA000007; BAB38724.1; -; Genomic_DNA.
DR PIR; E91291; E91291.
DR PIR; G86132; G86132.
DR RefSeq; NP_313328.1; NC_002695.1.
DR RefSeq; WP_001303778.1; NZ_SWKA01000005.1.
DR AlphaFoldDB; P58245; -.
DR SMR; P58245; -.
DR STRING; 155864.EDL933_5682; -.
DR EnsemblBacteria; AAG59523; AAG59523; Z5940.
DR EnsemblBacteria; BAB38724; BAB38724; ECs_5301.
DR GeneID; 913622; -.
DR KEGG; ece:Z5940; -.
DR KEGG; ecs:ECs_5301; -.
DR PATRIC; fig|386585.9.peg.5543; -.
DR eggNOG; COG5464; Bacteria.
DR HOGENOM; CLU_059548_1_0_6; -.
DR Proteomes; UP000000558; Chromosome.
DR Proteomes; UP000002519; Chromosome.
DR GO; GO:0004519; F:endonuclease activity; IEA:UniProtKB-KW.
DR GO; GO:0006310; P:DNA recombination; IEA:UniProtKB-KW.
DR InterPro; IPR010106; RpnA.
DR InterPro; IPR006842; Transposase_31.
DR Pfam; PF04754; Transposase_31; 1.
DR TIGRFAMs; TIGR01784; T_den_put_tspse; 1.
PE 3: Inferred from homology;
KW DNA recombination; Endonuclease; Hydrolase; Magnesium; Nuclease;
KW Reference proteome.
FT CHAIN 1..260
FT /note="Recombination-promoting nuclease RpnD"
FT /id="PRO_0000169795"
SQ SEQUENCE 260 AA; 30489 MW; 49BED4A9FC824A82 CRC64;
MTNFTTSTPH DALFKSFLMH PDTARDFMEI HLPKDLRELC DLDSLKLESA SFVDEKLRAL
HSDILWSVKT REGDGYIYVV IEHQSREDIH MAFRLMRYSM AVMQRHIEHD KRRPLPLVIP
MLFYHGSRSP YPWSLCWLDE FADPTTARKL YNAAFPLVDI TVVPDDEIVQ HRRVALLELI
QKHIRQRDLM GLIDQLVVLL VTECANDSQI TALLNYILLT GDEERFNEFI SELTSRMPQH
RERIMTIAER IHNDDCRANS