ID   RPO1C_HALS3             Reviewed;         397 AA.
AC   B0R8D3; P15354; Q9HM80;
DT   14-APR-2009, integrated into UniProtKB/Swiss-Prot.
DT   08-APR-2008, sequence version 1.
DT   03-AUG-2022, entry version 68.
DE   RecName: Full=DNA-directed RNA polymerase subunit Rpo1C {ECO:0000255|HAMAP-Rule:MF_00411};
DE            EC=2.7.7.6 {ECO:0000255|HAMAP-Rule:MF_00411};
DE   AltName: Full=DNA-directed RNA polymerase subunit A'' {ECO:0000255|HAMAP-Rule:MF_00411};
DE   AltName: Full=DNA-directed RNA polymerase subunit C {ECO:0000303|PubMed:2495365};
DE            Short=Subunit C {ECO:0000303|PubMed:2495365};
GN   Name=rpo1C {ECO:0000255|HAMAP-Rule:MF_00411};
GN   Synonyms=rpoA2 {ECO:0000255|HAMAP-Rule:MF_00411};
GN   OrderedLocusNames=OE_4739R;
OS   Halobacterium salinarum (strain ATCC 29341 / DSM 671 / R1).
OC   Archaea; Euryarchaeota; Stenosarchaea group; Halobacteria; Halobacteriales;
OC   Halobacteriaceae; Halobacterium.
OX   NCBI_TaxID=478009;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA], PROTEIN SEQUENCE OF 2-10, AND SUBUNIT.
RC   STRAIN=ATCC 29341 / DSM 671 / R1;
RX   PubMed=2495365; DOI=10.1016/0022-2836(89)90519-6;
RA   Leffers H., Gropp F., Lottspeich F., Zillig W., Garrett R.A.;
RT   "Sequence, organization, transcription and evolution of RNA polymerase
RT   subunit genes from the archaebacterial extreme halophiles Halobacterium
RT   halobium and Halococcus morrhuae.";
RL   J. Mol. Biol. 206:1-17(1989).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 29341 / DSM 671 / R1;
RX   PubMed=18313895; DOI=10.1016/j.ygeno.2008.01.001;
RA   Pfeiffer F., Schuster S.C., Broicher A., Falb M., Palm P., Rodewald K.,
RA   Ruepp A., Soppa J., Tittor J., Oesterhelt D.;
RT   "Evolution in the laboratory: the genome of Halobacterium salinarum strain
RT   R1 compared to that of strain NRC-1.";
RL   Genomics 91:335-346(2008).
CC   -!- FUNCTION: DNA-dependent RNA polymerase (RNAP) catalyzes the
CC       transcription of DNA into RNA using the four ribonucleoside
CC       triphosphates as substrates. Forms part of the jaw domain.
CC       {ECO:0000255|HAMAP-Rule:MF_00411}.
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=a ribonucleoside 5'-triphosphate + RNA(n) = diphosphate +
CC         RNA(n+1); Xref=Rhea:RHEA:21248, Rhea:RHEA-COMP:14527, Rhea:RHEA-
CC         COMP:17342, ChEBI:CHEBI:33019, ChEBI:CHEBI:61557, ChEBI:CHEBI:140395;
CC         EC=2.7.7.6; Evidence={ECO:0000255|HAMAP-Rule:MF_00411};
CC   -!- SUBUNIT: Part of the RNA polymerase complex. {ECO:0000255|HAMAP-
CC       Rule:MF_00411, ECO:0000269|PubMed:2495365}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000255|HAMAP-Rule:MF_00411}.
CC   -!- SIMILARITY: Belongs to the RNA polymerase beta' chain family.
CC       {ECO:0000255|HAMAP-Rule:MF_00411}.
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DR   EMBL; X57144; CAA40427.1; -; Genomic_DNA.
DR   EMBL; AM774415; CAP15002.1; -; Genomic_DNA.
DR   PIR; S03577; S03577.
DR   RefSeq; WP_010903995.1; NC_010364.1.
DR   AlphaFoldDB; B0R8D3; -.
DR   SMR; B0R8D3; -.
DR   PRIDE; B0R8D3; -.
DR   EnsemblBacteria; CAP15002; CAP15002; OE_4739R.
DR   GeneID; 5954046; -.
DR   KEGG; hsl:OE_4739R; -.
DR   HOGENOM; CLU_037097_1_0_2; -.
DR   OMA; TPMMTVY; -.
DR   PhylomeDB; B0R8D3; -.
DR   Proteomes; UP000001321; Chromosome.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0000428; C:DNA-directed RNA polymerase complex; IEA:UniProtKB-KW.
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-UniRule.
DR   GO; GO:0003899; F:DNA-directed 5'-3' RNA polymerase activity; IEA:UniProtKB-UniRule.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-UniRule.
DR   CDD; cd06528; RNAP_A; 1.
DR   HAMAP; MF_00411; RNApol_arch_Rpo1C; 1.
DR   InterPro; IPR045867; DNA-dir_RpoC_beta_prime.
DR   InterPro; IPR007081; RNA_pol_Rpb1_5.
DR   InterPro; IPR012757; RPO1C.
DR   PANTHER; PTHR19376; PTHR19376; 1.
DR   Pfam; PF04998; RNA_pol_Rpb1_5; 1.
DR   TIGRFAMs; TIGR02389; RNA_pol_rpoA2; 1.
PE   1: Evidence at protein level;
KW   Cytoplasm; Direct protein sequencing; DNA-binding;
KW   DNA-directed RNA polymerase; Nucleotidyltransferase; Transcription;
KW   Transferase.
FT   INIT_MET        1
FT                   /note="Removed"
FT                   /evidence="ECO:0000269|PubMed:2495365"
FT   CHAIN           2..397
FT                   /note="DNA-directed RNA polymerase subunit Rpo1C"
FT                   /id="PRO_1000194737"
SQ   SEQUENCE   397 AA;  43750 MW;  453E5DBAEC78A1DC CRC64;
     MTEFDVTDGV HDVIEDTELP RRLKDEVLAT AEERGVTKSQ ANEIATAVEA QYLDTRVDPL
     DPVGTVSAQS IGEPGTQMTM NTFHYAGVAE MDVTQGLPRL IELVDARKTP DTPVMEVYLE
     DEYAEERERA HEVVWKIEAT KILALGDIST NVADMVVRID LNEDTLQERW PRVDSTTQIA
     GEVAETIEGN LGVTVTQDGT ILEFGPSEPS YRELLQLVEQ LRDIVFKGIE EVSRVVIRRE
     ETERGEEFVL YTEGSAFKKA LKIEGVDATR TSCNNIHEVH KTLGIEAARE AIINETMTTL
     EEQGLDDVNI RHLMLVADIM TNDGTIESIG RHGISGNKNS VLARAAFEVT VNHLLDAAIH
     GESDDLDGVI ENVIVGKPVR LGTGDVDLRM GATQTSD