RPO1C_HALSA
ID RPO1C_HALSA Reviewed; 397 AA.
AC P0CX07; P15354; Q9HM80;
DT 28-JUN-2011, integrated into UniProtKB/Swiss-Prot.
DT 28-JUN-2011, sequence version 1.
DT 03-AUG-2022, entry version 48.
DE RecName: Full=DNA-directed RNA polymerase subunit Rpo1C {ECO:0000255|HAMAP-Rule:MF_00411};
DE EC=2.7.7.6 {ECO:0000255|HAMAP-Rule:MF_00411};
DE AltName: Full=DNA-directed RNA polymerase subunit A'' {ECO:0000255|HAMAP-Rule:MF_00411};
GN Name=rpo1C {ECO:0000255|HAMAP-Rule:MF_00411};
GN Synonyms=rpoA2 {ECO:0000255|HAMAP-Rule:MF_00411},
GN rpoC {ECO:0000303|PubMed:11016950}; OrderedLocusNames=VNG_2662G;
OS Halobacterium salinarum (strain ATCC 700922 / JCM 11081 / NRC-1)
OS (Halobacterium halobium).
OC Archaea; Euryarchaeota; Stenosarchaea group; Halobacteria; Halobacteriales;
OC Halobacteriaceae; Halobacterium.
OX NCBI_TaxID=64091;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 700922 / JCM 11081 / NRC-1;
RX PubMed=11016950; DOI=10.1073/pnas.190337797;
RA Ng W.V., Kennedy S.P., Mahairas G.G., Berquist B., Pan M., Shukla H.D.,
RA Lasky S.R., Baliga N.S., Thorsson V., Sbrogna J., Swartzell S., Weir D.,
RA Hall J., Dahl T.A., Welti R., Goo Y.A., Leithauser B., Keller K., Cruz R.,
RA Danson M.J., Hough D.W., Maddocks D.G., Jablonski P.E., Krebs M.P.,
RA Angevine C.M., Dale H., Isenbarger T.A., Peck R.F., Pohlschroder M.,
RA Spudich J.L., Jung K.-H., Alam M., Freitas T., Hou S., Daniels C.J.,
RA Dennis P.P., Omer A.D., Ebhardt H., Lowe T.M., Liang P., Riley M., Hood L.,
RA DasSarma S.;
RT "Genome sequence of Halobacterium species NRC-1.";
RL Proc. Natl. Acad. Sci. U.S.A. 97:12176-12181(2000).
CC -!- FUNCTION: DNA-dependent RNA polymerase (RNAP) catalyzes the
CC transcription of DNA into RNA using the four ribonucleoside
CC triphosphates as substrates. Forms part of the jaw domain.
CC {ECO:0000255|HAMAP-Rule:MF_00411}.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=a ribonucleoside 5'-triphosphate + RNA(n) = diphosphate +
CC RNA(n+1); Xref=Rhea:RHEA:21248, Rhea:RHEA-COMP:14527, Rhea:RHEA-
CC COMP:17342, ChEBI:CHEBI:33019, ChEBI:CHEBI:61557, ChEBI:CHEBI:140395;
CC EC=2.7.7.6; Evidence={ECO:0000255|HAMAP-Rule:MF_00411};
CC -!- SUBUNIT: Part of the RNA polymerase complex. {ECO:0000255|HAMAP-
CC Rule:MF_00411}.
CC -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000255|HAMAP-Rule:MF_00411}.
CC -!- SIMILARITY: Belongs to the RNA polymerase beta' chain family.
CC {ECO:0000255|HAMAP-Rule:MF_00411}.
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DR EMBL; AE004437; AAG20691.1; -; Genomic_DNA.
DR PIR; G84415; G84415.
DR RefSeq; WP_010903995.1; NC_002607.1.
DR AlphaFoldDB; P0CX07; -.
DR SMR; P0CX07; -.
DR STRING; 64091.VNG_2662G; -.
DR PaxDb; P0CX07; -.
DR EnsemblBacteria; AAG20691; AAG20691; VNG_2662G.
DR GeneID; 5954046; -.
DR KEGG; hal:VNG_2662G; -.
DR PATRIC; fig|64091.14.peg.2068; -.
DR HOGENOM; CLU_037097_1_0_2; -.
DR InParanoid; P0CX07; -.
DR OMA; TPMMTVY; -.
DR OrthoDB; 66811at2157; -.
DR PhylomeDB; P0CX07; -.
DR Proteomes; UP000000554; Chromosome.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR GO; GO:0000428; C:DNA-directed RNA polymerase complex; IEA:UniProtKB-KW.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-UniRule.
DR GO; GO:0003899; F:DNA-directed 5'-3' RNA polymerase activity; IEA:UniProtKB-UniRule.
DR GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-UniRule.
DR CDD; cd06528; RNAP_A; 1.
DR HAMAP; MF_00411; RNApol_arch_Rpo1C; 1.
DR InterPro; IPR045867; DNA-dir_RpoC_beta_prime.
DR InterPro; IPR007081; RNA_pol_Rpb1_5.
DR InterPro; IPR012757; RPO1C.
DR PANTHER; PTHR19376; PTHR19376; 1.
DR Pfam; PF04998; RNA_pol_Rpb1_5; 1.
DR TIGRFAMs; TIGR02389; RNA_pol_rpoA2; 1.
PE 3: Inferred from homology;
KW Cytoplasm; DNA-binding; DNA-directed RNA polymerase;
KW Nucleotidyltransferase; Reference proteome; Transcription; Transferase.
FT INIT_MET 1
FT /note="Removed"
FT /evidence="ECO:0000250"
FT CHAIN 2..397
FT /note="DNA-directed RNA polymerase subunit Rpo1C"
FT /id="PRO_0000074013"
SQ SEQUENCE 397 AA; 43750 MW; 453E5DBAEC78A1DC CRC64;
MTEFDVTDGV HDVIEDTELP RRLKDEVLAT AEERGVTKSQ ANEIATAVEA QYLDTRVDPL
DPVGTVSAQS IGEPGTQMTM NTFHYAGVAE MDVTQGLPRL IELVDARKTP DTPVMEVYLE
DEYAEERERA HEVVWKIEAT KILALGDIST NVADMVVRID LNEDTLQERW PRVDSTTQIA
GEVAETIEGN LGVTVTQDGT ILEFGPSEPS YRELLQLVEQ LRDIVFKGIE EVSRVVIRRE
ETERGEEFVL YTEGSAFKKA LKIEGVDATR TSCNNIHEVH KTLGIEAARE AIINETMTTL
EEQGLDDVNI RHLMLVADIM TNDGTIESIG RHGISGNKNS VLARAAFEVT VNHLLDAAIH
GESDDLDGVI ENVIVGKPVR LGTGDVDLRM GATQTSD
