RPO1C_SULIN
ID RPO1C_SULIN Reviewed; 392 AA.
AC C3NFS2;
DT 22-SEP-2009, integrated into UniProtKB/Swiss-Prot.
DT 16-JUN-2009, sequence version 1.
DT 03-AUG-2022, entry version 62.
DE RecName: Full=DNA-directed RNA polymerase subunit Rpo1C {ECO:0000255|HAMAP-Rule:MF_00411};
DE EC=2.7.7.6 {ECO:0000255|HAMAP-Rule:MF_00411};
DE AltName: Full=DNA-directed RNA polymerase subunit A'' {ECO:0000255|HAMAP-Rule:MF_00411};
GN Name=rpo1C {ECO:0000255|HAMAP-Rule:MF_00411};
GN Synonyms=rpoA2 {ECO:0000255|HAMAP-Rule:MF_00411};
GN OrderedLocusNames=YN1551_0931;
OS Sulfolobus islandicus (strain Y.N.15.51 / Yellowstone #2).
OC Archaea; Crenarchaeota; Thermoprotei; Sulfolobales; Sulfolobaceae;
OC Sulfolobus.
OX NCBI_TaxID=419942;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Y.N.15.51 / Yellowstone #2;
RX PubMed=19435847; DOI=10.1073/pnas.0808945106;
RA Reno M.L., Held N.L., Fields C.J., Burke P.V., Whitaker R.J.;
RT "Biogeography of the Sulfolobus islandicus pan-genome.";
RL Proc. Natl. Acad. Sci. U.S.A. 106:8605-8610(2009).
CC -!- FUNCTION: DNA-dependent RNA polymerase (RNAP) catalyzes the
CC transcription of DNA into RNA using the four ribonucleoside
CC triphosphates as substrates. Forms part of the jaw domain.
CC {ECO:0000255|HAMAP-Rule:MF_00411}.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=a ribonucleoside 5'-triphosphate + RNA(n) = diphosphate +
CC RNA(n+1); Xref=Rhea:RHEA:21248, Rhea:RHEA-COMP:14527, Rhea:RHEA-
CC COMP:17342, ChEBI:CHEBI:33019, ChEBI:CHEBI:61557, ChEBI:CHEBI:140395;
CC EC=2.7.7.6; Evidence={ECO:0000255|HAMAP-Rule:MF_00411};
CC -!- SUBUNIT: Part of the RNA polymerase complex. {ECO:0000255|HAMAP-
CC Rule:MF_00411}.
CC -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000255|HAMAP-Rule:MF_00411}.
CC -!- SIMILARITY: Belongs to the RNA polymerase beta' chain family.
CC {ECO:0000255|HAMAP-Rule:MF_00411}.
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DR EMBL; CP001404; ACP48040.1; -; Genomic_DNA.
DR RefSeq; WP_012711886.1; NC_012623.1.
DR AlphaFoldDB; C3NFS2; -.
DR SMR; C3NFS2; -.
DR EnsemblBacteria; ACP48040; ACP48040; YN1551_0931.
DR GeneID; 7813071; -.
DR GeneID; 7939647; -.
DR GeneID; 8761976; -.
DR KEGG; sin:YN1551_0931; -.
DR HOGENOM; CLU_037097_1_0_2; -.
DR OMA; TPMMTVY; -.
DR Proteomes; UP000006818; Chromosome.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR GO; GO:0000428; C:DNA-directed RNA polymerase complex; IEA:UniProtKB-KW.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-UniRule.
DR GO; GO:0003899; F:DNA-directed 5'-3' RNA polymerase activity; IEA:UniProtKB-UniRule.
DR GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-UniRule.
DR CDD; cd06528; RNAP_A; 1.
DR HAMAP; MF_00411; RNApol_arch_Rpo1C; 1.
DR InterPro; IPR045867; DNA-dir_RpoC_beta_prime.
DR InterPro; IPR007081; RNA_pol_Rpb1_5.
DR InterPro; IPR012757; RPO1C.
DR PANTHER; PTHR19376; PTHR19376; 1.
DR Pfam; PF04998; RNA_pol_Rpb1_5; 1.
DR TIGRFAMs; TIGR02389; RNA_pol_rpoA2; 1.
PE 3: Inferred from homology;
KW Cytoplasm; DNA-binding; DNA-directed RNA polymerase;
KW Nucleotidyltransferase; Transcription; Transferase.
FT CHAIN 1..392
FT /note="DNA-directed RNA polymerase subunit Rpo1C"
FT /id="PRO_1000205987"
SQ SEQUENCE 392 AA; 43390 MW; 982D42722F539826 CRC64;
MIDEKDKSYL EEKVKQASNI LPQKIVEDLK NLISNKEVLV TRDEIDKIFD LAIKEYSEGL
IAPGEAIGIV AAQSVGEPGT QMTLRTFHFA GIRELNVTLG LPRLIEIVDA KKVPSTPMMT
IYLTDEYKHD KEKALEVARK LEYTKIENVV SSTSIDIASM SIILQLDNEM LKDKGVTVDD
VKKAINRLKL GEFVIDESEG NTLNISFANI DSIAALFKLR DKILNTKIKG IKGIKRAIVQ
KKGDEYIILT DGSNLSGVLS VKGVDIAKVE TNNIREIEEV FGIEAAREII IREISKVLAE
QGLDVDMRHI LLVADVMTRT GVVRQIGRHG VTGEKNSVLA RAAFEVTVKH LLDAAARGDV
EEFKGVVENI IIGHPIKLGT GMVELTMRPI LR
