RPO1C_THECE
ID RPO1C_THECE Reviewed; 393 AA.
AC P29158;
DT 01-DEC-1992, integrated into UniProtKB/Swiss-Prot.
DT 01-JUL-1993, sequence version 2.
DT 03-AUG-2022, entry version 74.
DE RecName: Full=DNA-directed RNA polymerase subunit Rpo1C {ECO:0000255|HAMAP-Rule:MF_00411};
DE EC=2.7.7.6 {ECO:0000255|HAMAP-Rule:MF_00411};
DE AltName: Full=DNA-directed RNA polymerase subunit A'' {ECO:0000255|HAMAP-Rule:MF_00411};
GN Name=rpo1C {ECO:0000255|HAMAP-Rule:MF_00411};
GN Synonyms=rpoA2 {ECO:0000255|HAMAP-Rule:MF_00411};
OS Thermococcus celer.
OC Archaea; Euryarchaeota; Thermococci; Thermococcales; Thermococcaceae;
OC Thermococcus.
OX NCBI_TaxID=2264;
RN [1]
RP NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC STRAIN=ATCC 35543 / DSM 2476 / JCM 8558 / Vu 13;
RX PubMed=1408768; DOI=10.1093/nar/20.17.4659;
RA Klenk H.-P., Schwass V., Lottspeich F., Zillig W.;
RT "Nucleotide sequence of the genes encoding the three largest subunits of
RT the DNA-dependent RNA polymerase from the archaeum Thermococcus celer.";
RL Nucleic Acids Res. 20:4659-4659(1992).
RN [2]
RP NUCLEOTIDE SEQUENCE [GENOMIC DNA] OF 195-393.
RC STRAIN=ATCC 35543 / DSM 2476 / JCM 8558 / Vu 13;
RX PubMed=1840672; DOI=10.1093/nar/19.21.6047;
RA Klenk H.-P., Schwass V., Zillig W.;
RT "Nucleotide sequence of the genes encoding the L30, S12 and S7 equivalent
RT ribosomal proteins from the archaeum Thermococcus celer.";
RL Nucleic Acids Res. 19:6047-6047(1991).
CC -!- FUNCTION: DNA-dependent RNA polymerase (RNAP) catalyzes the
CC transcription of DNA into RNA using the four ribonucleoside
CC triphosphates as substrates. Forms part of the jaw domain.
CC {ECO:0000255|HAMAP-Rule:MF_00411}.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=a ribonucleoside 5'-triphosphate + RNA(n) = diphosphate +
CC RNA(n+1); Xref=Rhea:RHEA:21248, Rhea:RHEA-COMP:14527, Rhea:RHEA-
CC COMP:17342, ChEBI:CHEBI:33019, ChEBI:CHEBI:61557, ChEBI:CHEBI:140395;
CC EC=2.7.7.6; Evidence={ECO:0000255|HAMAP-Rule:MF_00411};
CC -!- SUBUNIT: Part of the RNA polymerase complex. {ECO:0000255|HAMAP-
CC Rule:MF_00411}.
CC -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000255|HAMAP-Rule:MF_00411}.
CC -!- SIMILARITY: Belongs to the RNA polymerase beta' chain family.
CC {ECO:0000255|HAMAP-Rule:MF_00411}.
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DR EMBL; X67313; CAA47724.1; -; Genomic_DNA.
DR EMBL; X60305; CAA42846.1; -; Genomic_DNA.
DR PIR; S25565; S25565.
DR AlphaFoldDB; P29158; -.
DR SMR; P29158; -.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR GO; GO:0000428; C:DNA-directed RNA polymerase complex; IEA:UniProtKB-KW.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-UniRule.
DR GO; GO:0003899; F:DNA-directed 5'-3' RNA polymerase activity; IEA:UniProtKB-UniRule.
DR GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-UniRule.
DR CDD; cd06528; RNAP_A; 1.
DR HAMAP; MF_00411; RNApol_arch_Rpo1C; 1.
DR InterPro; IPR045867; DNA-dir_RpoC_beta_prime.
DR InterPro; IPR007081; RNA_pol_Rpb1_5.
DR InterPro; IPR012757; RPO1C.
DR PANTHER; PTHR19376; PTHR19376; 1.
DR Pfam; PF04998; RNA_pol_Rpb1_5; 1.
DR TIGRFAMs; TIGR02389; RNA_pol_rpoA2; 1.
PE 3: Inferred from homology;
KW Cytoplasm; DNA-binding; DNA-directed RNA polymerase;
KW Nucleotidyltransferase; Transcription; Transferase.
FT CHAIN 1..393
FT /note="DNA-directed RNA polymerase subunit Rpo1C"
FT /id="PRO_0000074029"
SQ SEQUENCE 393 AA; 43888 MW; 23BFAD738E10792E CRC64;
MVAAKTIKGM VDKAELPDNI KEELYAKLIE YNKKYKLKKA EVQAIIDETV KEYQKALIEP
GEAIGTVAAQ SIGEPSTQMT LNTFHYAGVA EINVTLGLPR IIEIVDARKN PSTPIMTVYL
DEEHRYDREK ALEVARRIEG TSLENLARET TIDILNFEFI VEIDPERLEK AGLDMERIQR
KLESSFKSAE FEVDGYTVIM RPKKVGKISS LRRLAEKVKK HRLKGLSRVG KTVITKDSKT
GEYIIRTEGS NFKQVLKVPG VDPTRTRTND IREIAEVLGI EAARNAIIDE ILKTMEEQGL
EVDVRHIMLV ADMMTLDGVI RPIGRHGIVG EKASVLARAA FEITTQHLFE AAERGAVDPL
NGVVENVLIG QPVPVGTGTV KLAMNLPLRP KRE
