ID   RPO1C_THEVO             Reviewed;         508 AA.
AC   Q979F5;
DT   15-MAY-2002, integrated into UniProtKB/Swiss-Prot.
DT   01-OCT-2001, sequence version 1.
DT   03-AUG-2022, entry version 96.
DE   RecName: Full=DNA-directed RNA polymerase subunit Rpo1C {ECO:0000255|HAMAP-Rule:MF_00411};
DE            EC=2.7.7.6 {ECO:0000255|HAMAP-Rule:MF_00411};
DE   AltName: Full=DNA-directed RNA polymerase subunit A'' {ECO:0000255|HAMAP-Rule:MF_00411};
GN   Name=rpo1C {ECO:0000255|HAMAP-Rule:MF_00411};
GN   Synonyms=rpoA2 {ECO:0000255|HAMAP-Rule:MF_00411}; OrderedLocusNames=TV1206;
GN   ORFNames=TVG1233699;
OS   Thermoplasma volcanium (strain ATCC 51530 / DSM 4299 / JCM 9571 / NBRC
OS   15438 / GSS1).
OC   Archaea; Candidatus Thermoplasmatota; Thermoplasmata; Thermoplasmatales;
OC   Thermoplasmataceae; Thermoplasma.
OX   NCBI_TaxID=273116;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 51530 / DSM 4299 / JCM 9571 / NBRC 15438 / GSS1;
RX   PubMed=11121031; DOI=10.1073/pnas.97.26.14257;
RA   Kawashima T., Amano N., Koike H., Makino S., Higuchi S., Kawashima-Ohya Y.,
RA   Watanabe K., Yamazaki M., Kanehori K., Kawamoto T., Nunoshiba T.,
RA   Yamamoto Y., Aramaki H., Makino K., Suzuki M.;
RT   "Archaeal adaptation to higher temperatures revealed by genomic sequence of
RT   Thermoplasma volcanium.";
RL   Proc. Natl. Acad. Sci. U.S.A. 97:14257-14262(2000).
CC   -!- FUNCTION: DNA-dependent RNA polymerase (RNAP) catalyzes the
CC       transcription of DNA into RNA using the four ribonucleoside
CC       triphosphates as substrates. Forms part of the jaw domain.
CC       {ECO:0000255|HAMAP-Rule:MF_00411}.
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=a ribonucleoside 5'-triphosphate + RNA(n) = diphosphate +
CC         RNA(n+1); Xref=Rhea:RHEA:21248, Rhea:RHEA-COMP:14527, Rhea:RHEA-
CC         COMP:17342, ChEBI:CHEBI:33019, ChEBI:CHEBI:61557, ChEBI:CHEBI:140395;
CC         EC=2.7.7.6; Evidence={ECO:0000255|HAMAP-Rule:MF_00411};
CC   -!- SUBUNIT: Part of the RNA polymerase complex. {ECO:0000255|HAMAP-
CC       Rule:MF_00411}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000255|HAMAP-Rule:MF_00411}.
CC   -!- SIMILARITY: Belongs to the RNA polymerase beta' chain family.
CC       {ECO:0000255|HAMAP-Rule:MF_00411}.
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DR   EMBL; BA000011; BAB60348.1; -; Genomic_DNA.
DR   AlphaFoldDB; Q979F5; -.
DR   SMR; Q979F5; -.
DR   STRING; 273116.14325444; -.
DR   EnsemblBacteria; BAB60348; BAB60348; BAB60348.
DR   KEGG; tvo:TVG1233699; -.
DR   eggNOG; arCOG04256; Archaea.
DR   HOGENOM; CLU_037097_1_0_2; -.
DR   OMA; TPMMTVY; -.
DR   PhylomeDB; Q979F5; -.
DR   Proteomes; UP000001017; Chromosome.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0000428; C:DNA-directed RNA polymerase complex; IEA:UniProtKB-KW.
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-UniRule.
DR   GO; GO:0003899; F:DNA-directed 5'-3' RNA polymerase activity; IEA:UniProtKB-UniRule.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-UniRule.
DR   CDD; cd06528; RNAP_A; 1.
DR   HAMAP; MF_00411; RNApol_arch_Rpo1C; 1.
DR   InterPro; IPR045867; DNA-dir_RpoC_beta_prime.
DR   InterPro; IPR007081; RNA_pol_Rpb1_5.
DR   InterPro; IPR012757; RPO1C.
DR   PANTHER; PTHR19376; PTHR19376; 1.
DR   Pfam; PF04998; RNA_pol_Rpb1_5; 1.
DR   TIGRFAMs; TIGR02389; RNA_pol_rpoA2; 1.
PE   3: Inferred from homology;
KW   Cytoplasm; DNA-binding; DNA-directed RNA polymerase;
KW   Nucleotidyltransferase; Transcription; Transferase.
FT   CHAIN           1..508
FT                   /note="DNA-directed RNA polymerase subunit Rpo1C"
FT                   /id="PRO_0000074030"
FT   REGION          1..123
FT                   /note="Unknown"
FT   REGION          124..508
FT                   /note="DNA-directed RNA polymerase subunit Rpo1C"
SQ   SEQUENCE   508 AA;  56950 MW;  0B17ABCBFE0118FE CRC64;
     MIIWKDTAKN MSLLSKSVPA KYAVDFEVPK GITEGYVTSD KKRFTYHVSI SSVAPYSNES
     DVIQKKKSGL KSIMEIEKIQ KIEPISIMEF RSSGKRIDEL LTYAIAERET AEIREKYEYE
     KKVSSQVLDV IAEAKKLGYN IPESVAEEIL RRKEEWGEKK YREILKRIGE EIQDELIDPY
     EAVGIIAAQS IGEPGTQMTM RTFHFAGVRE MNVTLGLPRL IEIVDARRIP STPSMTIYLK
     PEFETNDEVV MDVVKRLENT SVSDVADIIT DIGELTITVR PDPNKMNDRL INQDDLVNAI
     YKVKGVTVME ESGQIIVKPQ QESFKKLYLL QEQIKALPIK GISGIKRAIA RVEGKEHRWV
     IYTQGSNLKD VLEVDEVDPT RTYTNDIVEI ATVLGIEAAR NAILNEAQRT LQEQGLNVDV
     RHLMLVADMM TFSGSVRAVG RTGISGRKSS VLARAAFEIT TKHLLRAGIM GEVDKLAGVA
     ENIIVGQPIT LGTGAVDIIY KGYPKTKK