ID   RPO5_HALS3              Reviewed;          75 AA.
AC   B0R8D7; P15740; Q9HM76;
DT   24-MAR-2009, integrated into UniProtKB/Swiss-Prot.
DT   08-APR-2008, sequence version 1.
DT   03-AUG-2022, entry version 73.
DE   RecName: Full=DNA-directed RNA polymerase subunit Rpo5 {ECO:0000255|HAMAP-Rule:MF_00025};
DE            EC=2.7.7.6 {ECO:0000255|HAMAP-Rule:MF_00025};
DE   AltName: Full=DNA-directed RNA polymerase subunit H {ECO:0000255|HAMAP-Rule:MF_00025};
GN   Name=rpo5 {ECO:0000255|HAMAP-Rule:MF_00025};
GN   Synonyms=rpoH {ECO:0000255|HAMAP-Rule:MF_00025};
GN   OrderedLocusNames=OE_4743R;
OS   Halobacterium salinarum (strain ATCC 29341 / DSM 671 / R1).
OC   Archaea; Euryarchaeota; Stenosarchaea group; Halobacteria; Halobacteriales;
OC   Halobacteriaceae; Halobacterium.
OX   NCBI_TaxID=478009;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA], AND SUBUNIT.
RC   STRAIN=ATCC 29341 / DSM 671 / R1;
RX   PubMed=2495365; DOI=10.1016/0022-2836(89)90519-6;
RA   Leffers H., Gropp F., Lottspeich F., Zillig W., Garrett R.A.;
RT   "Sequence, organization, transcription and evolution of RNA polymerase
RT   subunit genes from the archaebacterial extreme halophiles Halobacterium
RT   halobium and Halococcus morrhuae.";
RL   J. Mol. Biol. 206:1-17(1989).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 29341 / DSM 671 / R1;
RX   PubMed=18313895; DOI=10.1016/j.ygeno.2008.01.001;
RA   Pfeiffer F., Schuster S.C., Broicher A., Falb M., Palm P., Rodewald K.,
RA   Ruepp A., Soppa J., Tittor J., Oesterhelt D.;
RT   "Evolution in the laboratory: the genome of Halobacterium salinarum strain
RT   R1 compared to that of strain NRC-1.";
RL   Genomics 91:335-346(2008).
CC   -!- FUNCTION: DNA-dependent RNA polymerase (RNAP) catalyzes the
CC       transcription of DNA into RNA using the four ribonucleoside
CC       triphosphates as substrates. {ECO:0000255|HAMAP-Rule:MF_00025}.
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=a ribonucleoside 5'-triphosphate + RNA(n) = diphosphate +
CC         RNA(n+1); Xref=Rhea:RHEA:21248, Rhea:RHEA-COMP:14527, Rhea:RHEA-
CC         COMP:17342, ChEBI:CHEBI:33019, ChEBI:CHEBI:61557, ChEBI:CHEBI:140395;
CC         EC=2.7.7.6; Evidence={ECO:0000255|HAMAP-Rule:MF_00025};
CC   -!- SUBUNIT: Part of the RNA polymerase complex. {ECO:0000255|HAMAP-
CC       Rule:MF_00025, ECO:0000269|PubMed:2495365}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000255|HAMAP-Rule:MF_00025}.
CC   -!- SIMILARITY: Belongs to the archaeal Rpo5/eukaryotic RPB5 RNA polymerase
CC       subunit family. {ECO:0000255|HAMAP-Rule:MF_00025}.
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DR   EMBL; X57144; CAA40423.1; -; Genomic_DNA.
DR   EMBL; AM774415; CAP15006.1; -; Genomic_DNA.
DR   PIR; S03578; S03578.
DR   RefSeq; WP_010903999.1; NC_010364.1.
DR   AlphaFoldDB; B0R8D7; -.
DR   SMR; B0R8D7; -.
DR   EnsemblBacteria; CAP15006; CAP15006; OE_4743R.
DR   GeneID; 55593111; -.
DR   GeneID; 60510059; -.
DR   GeneID; 62887875; -.
DR   GeneID; 63554706; -.
DR   KEGG; hsl:OE_4743R; -.
DR   HOGENOM; CLU_058320_4_0_2; -.
DR   OMA; PKIYHDD; -.
DR   PhylomeDB; B0R8D7; -.
DR   Proteomes; UP000001321; Chromosome.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0000428; C:DNA-directed RNA polymerase complex; IEA:UniProtKB-KW.
DR   GO; GO:0003677; F:DNA binding; IEA:InterPro.
DR   GO; GO:0003899; F:DNA-directed 5'-3' RNA polymerase activity; IEA:UniProtKB-UniRule.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-UniRule.
DR   Gene3D; 3.90.940.20; -; 1.
DR   HAMAP; MF_00025; RNApol_Rpo5_RPB5; 1.
DR   InterPro; IPR014381; Arch_Rpo5/euc_Rpb5.
DR   InterPro; IPR000783; RNA_pol_subH/Rpb5_C.
DR   InterPro; IPR020608; RNA_pol_subH/Rpb5_CS.
DR   InterPro; IPR035913; RPB5-like_sf.
DR   Pfam; PF01191; RNA_pol_Rpb5_C; 1.
DR   SUPFAM; SSF55287; SSF55287; 1.
DR   PROSITE; PS01110; RNA_POL_H_23KD; 1.
PE   1: Evidence at protein level;
KW   Cytoplasm; DNA-directed RNA polymerase; Nucleotidyltransferase;
KW   Transcription; Transferase.
FT   CHAIN           1..75
FT                   /note="DNA-directed RNA polymerase subunit Rpo5"
FT                   /id="PRO_1000090208"
SQ   SEQUENCE   75 AA;  8507 MW;  CA23333FF48A6F25 CRC64;
     MVDVSQHELV PEHTVLDEET LDGVLADYDI DRTELPKIKY KDPALPDNAE IGDVVEIVRD
     SRTTDEAVVY RLVIE