ID   RPO6_HALMA              Reviewed;          57 AA.
AC   P29200; Q5V5Q4;
DT   01-DEC-1992, integrated into UniProtKB/Swiss-Prot.
DT   01-DEC-1992, sequence version 1.
DT   03-AUG-2022, entry version 121.
DE   RecName: Full=DNA-directed RNA polymerase subunit Rpo6 {ECO:0000255|HAMAP-Rule:MF_00192};
DE            EC=2.7.7.6 {ECO:0000255|HAMAP-Rule:MF_00192};
DE   AltName: Full=DNA-directed RNA polymerase subunit K {ECO:0000255|HAMAP-Rule:MF_00192};
GN   Name=rpo6 {ECO:0000255|HAMAP-Rule:MF_00192};
GN   Synonyms=rpoK {ECO:0000255|HAMAP-Rule:MF_00192};
GN   OrderedLocusNames=rrnAC0068;
OS   Haloarcula marismortui (strain ATCC 43049 / DSM 3752 / JCM 8966 / VKM
OS   B-1809) (Halobacterium marismortui).
OC   Archaea; Euryarchaeota; Stenosarchaea group; Halobacteria; Halobacteriales;
OC   Haloarculaceae; Haloarcula.
OX   NCBI_TaxID=272569;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RX   PubMed=1840597; DOI=10.1016/s0021-9258(18)54267-8;
RA   Kroemer W.J., Arndt E.;
RT   "Halobacterial S9 operon. Three ribosomal protein genes are cotranscribed
RT   with genes encoding a tRNA(Leu), the enolase, and a putative membrane
RT   protein in the archaebacterium Haloarcula (Halobacterium) marismortui.";
RL   J. Biol. Chem. 266:24573-24579(1991).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 43049 / DSM 3752 / JCM 8966 / VKM B-1809;
RX   PubMed=15520287; DOI=10.1101/gr.2700304;
RA   Baliga N.S., Bonneau R., Facciotti M.T., Pan M., Glusman G., Deutsch E.W.,
RA   Shannon P., Chiu Y., Weng R.S., Gan R.R., Hung P., Date S.V., Marcotte E.,
RA   Hood L., Ng W.V.;
RT   "Genome sequence of Haloarcula marismortui: a halophilic archaeon from the
RT   Dead Sea.";
RL   Genome Res. 14:2221-2234(2004).
RN   [3]
RP   SIMILARITY.
RX   PubMed=8045907; DOI=10.1128/jb.176.15.4754-4756.1994;
RA   McKune K., Woychik N.A.;
RT   "Halobacterial S9 operon contains two genes encoding proteins homologous to
RT   subunits shared by eukaryotic RNA polymerases I, II, and III.";
RL   J. Bacteriol. 176:4754-4756(1994).
CC   -!- FUNCTION: DNA-dependent RNA polymerase (RNAP) catalyzes the
CC       transcription of DNA into RNA using the four ribonucleoside
CC       triphosphates as substrates. {ECO:0000255|HAMAP-Rule:MF_00192}.
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=a ribonucleoside 5'-triphosphate + RNA(n) = diphosphate +
CC         RNA(n+1); Xref=Rhea:RHEA:21248, Rhea:RHEA-COMP:14527, Rhea:RHEA-
CC         COMP:17342, ChEBI:CHEBI:33019, ChEBI:CHEBI:61557, ChEBI:CHEBI:140395;
CC         EC=2.7.7.6; Evidence={ECO:0000255|HAMAP-Rule:MF_00192};
CC   -!- SUBUNIT: Part of the RNA polymerase complex. {ECO:0000255|HAMAP-
CC       Rule:MF_00192}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000255|HAMAP-Rule:MF_00192}.
CC   -!- SIMILARITY: Belongs to the archaeal Rpo6/eukaryotic RPB6 RNA polymerase
CC       subunit family. {ECO:0000255|HAMAP-Rule:MF_00192,
CC       ECO:0000305|PubMed:8045907}.
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DR   EMBL; M76567; AAA73100.1; -; Genomic_DNA.
DR   EMBL; AY596297; AAV45148.1; -; Genomic_DNA.
DR   PIR; E41715; E41715.
DR   RefSeq; WP_004516796.1; NZ_CP039138.1.
DR   AlphaFoldDB; P29200; -.
DR   SMR; P29200; -.
DR   STRING; 272569.rrnAC0068; -.
DR   EnsemblBacteria; AAV45148; AAV45148; rrnAC0068.
DR   GeneID; 40154383; -.
DR   GeneID; 64823165; -.
DR   KEGG; hma:rrnAC0068; -.
DR   PATRIC; fig|272569.17.peg.876; -.
DR   eggNOG; arCOG01268; Archaea.
DR   HOGENOM; CLU_112527_5_0_2; -.
DR   OMA; GTNRYEK; -.
DR   Proteomes; UP000001169; Chromosome I.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0000428; C:DNA-directed RNA polymerase complex; IEA:UniProtKB-KW.
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-UniRule.
DR   GO; GO:0003899; F:DNA-directed 5'-3' RNA polymerase activity; IEA:UniProtKB-UniRule.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-UniRule.
DR   Gene3D; 3.90.940.10; -; 1.
DR   HAMAP; MF_00192; RNApol_arch_Rpo6; 1.
DR   InterPro; IPR020708; DNA-dir_RNA_polK_14-18kDa_CS.
DR   InterPro; IPR006110; Pol_omega/Rpo6/RPB6.
DR   InterPro; IPR036161; RPB6/omega-like_sf.
DR   InterPro; IPR006111; Rpo6/Rpb6.
DR   Pfam; PF01192; RNA_pol_Rpb6; 1.
DR   PIRSF; PIRSF000778; RpoK/RPB6; 1.
DR   SUPFAM; SSF63562; SSF63562; 1.
DR   PROSITE; PS01111; RNA_POL_K_14KD; 1.
PE   3: Inferred from homology;
KW   Cytoplasm; DNA-directed RNA polymerase; Nucleotidyltransferase;
KW   Reference proteome; Transcription; Transferase.
FT   CHAIN           1..57
FT                   /note="DNA-directed RNA polymerase subunit Rpo6"
FT                   /id="PRO_0000133810"
SQ   SEQUENCE   57 AA;  6291 MW;  D299FDA1954D030F CRC64;
     MNAQESRYEK ARKLGARALQ LAHGAPVLIE TEHTQPILIA AEEYDAGVLP FTVNRSD