ID   RPO6_THEKO              Reviewed;          57 AA.
AC   Q5JJD0;
DT   30-AUG-2005, integrated into UniProtKB/Swiss-Prot.
DT   15-FEB-2005, sequence version 1.
DT   03-AUG-2022, entry version 99.
DE   RecName: Full=DNA-directed RNA polymerase subunit Rpo6 {ECO:0000255|HAMAP-Rule:MF_00192};
DE            EC=2.7.7.6 {ECO:0000255|HAMAP-Rule:MF_00192};
DE   AltName: Full=DNA-directed RNA polymerase subunit K {ECO:0000255|HAMAP-Rule:MF_00192};
GN   Name=rpo6 {ECO:0000255|HAMAP-Rule:MF_00192};
GN   Synonyms=rpoK {ECO:0000255|HAMAP-Rule:MF_00192}; OrderedLocusNames=TK1498;
OS   Thermococcus kodakarensis (strain ATCC BAA-918 / JCM 12380 / KOD1)
OS   (Pyrococcus kodakaraensis (strain KOD1)).
OC   Archaea; Euryarchaeota; Thermococci; Thermococcales; Thermococcaceae;
OC   Thermococcus.
OX   NCBI_TaxID=69014;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC BAA-918 / JCM 12380 / KOD1;
RX   PubMed=15710748; DOI=10.1101/gr.3003105;
RA   Fukui T., Atomi H., Kanai T., Matsumi R., Fujiwara S., Imanaka T.;
RT   "Complete genome sequence of the hyperthermophilic archaeon Thermococcus
RT   kodakaraensis KOD1 and comparison with Pyrococcus genomes.";
RL   Genome Res. 15:352-363(2005).
CC   -!- FUNCTION: DNA-dependent RNA polymerase (RNAP) catalyzes the
CC       transcription of DNA into RNA using the four ribonucleoside
CC       triphosphates as substrates. {ECO:0000255|HAMAP-Rule:MF_00192}.
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=a ribonucleoside 5'-triphosphate + RNA(n) = diphosphate +
CC         RNA(n+1); Xref=Rhea:RHEA:21248, Rhea:RHEA-COMP:14527, Rhea:RHEA-
CC         COMP:17342, ChEBI:CHEBI:33019, ChEBI:CHEBI:61557, ChEBI:CHEBI:140395;
CC         EC=2.7.7.6; Evidence={ECO:0000255|HAMAP-Rule:MF_00192};
CC   -!- SUBUNIT: Part of the RNA polymerase complex. {ECO:0000255|HAMAP-
CC       Rule:MF_00192}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000255|HAMAP-Rule:MF_00192}.
CC   -!- SIMILARITY: Belongs to the archaeal Rpo6/eukaryotic RPB6 RNA polymerase
CC       subunit family. {ECO:0000255|HAMAP-Rule:MF_00192}.
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DR   EMBL; AP006878; BAD85687.1; -; Genomic_DNA.
DR   RefSeq; WP_011250449.1; NC_006624.1.
DR   PDB; 4QIW; X-ray; 3.50 A; K/T=1-57.
DR   PDB; 6KF3; EM; 3.90 A; K=1-57.
DR   PDB; 6KF4; EM; 3.97 A; K=1-57.
DR   PDB; 6KF9; EM; 3.79 A; K=1-57.
DR   PDBsum; 4QIW; -.
DR   PDBsum; 6KF3; -.
DR   PDBsum; 6KF4; -.
DR   PDBsum; 6KF9; -.
DR   AlphaFoldDB; Q5JJD0; -.
DR   SMR; Q5JJD0; -.
DR   STRING; 69014.TK1498; -.
DR   EnsemblBacteria; BAD85687; BAD85687; TK1498.
DR   GeneID; 3234823; -.
DR   KEGG; tko:TK1498; -.
DR   PATRIC; fig|69014.16.peg.1458; -.
DR   eggNOG; arCOG01268; Archaea.
DR   HOGENOM; CLU_112527_5_0_2; -.
DR   InParanoid; Q5JJD0; -.
DR   OMA; HNRYEKA; -.
DR   OrthoDB; 126193at2157; -.
DR   PhylomeDB; Q5JJD0; -.
DR   Proteomes; UP000000536; Chromosome.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0000428; C:DNA-directed RNA polymerase complex; IEA:UniProtKB-KW.
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-UniRule.
DR   GO; GO:0003899; F:DNA-directed 5'-3' RNA polymerase activity; IEA:UniProtKB-UniRule.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-UniRule.
DR   Gene3D; 3.90.940.10; -; 1.
DR   HAMAP; MF_00192; RNApol_arch_Rpo6; 1.
DR   InterPro; IPR020708; DNA-dir_RNA_polK_14-18kDa_CS.
DR   InterPro; IPR006110; Pol_omega/Rpo6/RPB6.
DR   InterPro; IPR036161; RPB6/omega-like_sf.
DR   InterPro; IPR006111; Rpo6/Rpb6.
DR   Pfam; PF01192; RNA_pol_Rpb6; 1.
DR   PIRSF; PIRSF000778; RpoK/RPB6; 1.
DR   SUPFAM; SSF63562; SSF63562; 1.
DR   PROSITE; PS01111; RNA_POL_K_14KD; 1.
PE   1: Evidence at protein level;
KW   3D-structure; Cytoplasm; DNA-directed RNA polymerase;
KW   Nucleotidyltransferase; Reference proteome; Transcription; Transferase.
FT   CHAIN           1..57
FT                   /note="DNA-directed RNA polymerase subunit Rpo6"
FT                   /id="PRO_0000133821"
FT   HELIX           6..21
FT                   /evidence="ECO:0007829|PDB:4QIW"
FT   HELIX           36..45
FT                   /evidence="ECO:0007829|PDB:4QIW"
FT   STRAND          52..54
FT                   /evidence="ECO:0007829|PDB:4QIW"
SQ   SEQUENCE   57 AA;  6280 MW;  134BF6D6F3681AF4 CRC64;
     MFRYTRFEKA RIIGARALQI AMGAPVLIDV PEGITPLQAA LLEFEKGVIP ITVIRPS