ID   AB35G_ORYSJ             Reviewed;        1464 AA.
AC   Q8GU92; A0A0P0V536; Q0JLC6;
DT   16-MAY-2006, integrated into UniProtKB/Swiss-Prot.
DT   01-MAR-2003, sequence version 1.
DT   03-AUG-2022, entry version 110.
DE   RecName: Full=ABC transporter G family member 35 {ECO:0000303|PubMed:18299247};
DE            Short=OsABCG35 {ECO:0000303|PubMed:18299247};
DE   AltName: Full=Pleiotropic drug resistance protein 11 {ECO:0000303|PubMed:12644668, ECO:0000303|PubMed:16506311};
DE            Short=OsPDR11 {ECO:0000303|PubMed:16506311};
GN   Name=ABCG35 {ECO:0000303|PubMed:18299247};
GN   Synonyms=PDR11 {ECO:0000303|PubMed:12644668},
GN   PDR2 {ECO:0000303|PubMed:12430018, ECO:0000303|PubMed:16506311};
GN   OrderedLocusNames=Os01g0609200 {ECO:0000312|EMBL:BAF05452.1},
GN   LOC_Os01g42370; ORFNames=P0410E03.6 {ECO:0000312|EMBL:AP002844};
OS   Oryza sativa subsp. japonica (Rice).
OC   Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC   Spermatophyta; Magnoliopsida; Liliopsida; Poales; Poaceae; BOP clade;
OC   Oryzoideae; Oryzeae; Oryzinae; Oryza; Oryza sativa.
OX   NCBI_TaxID=39947;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RX   PubMed=12644668; DOI=10.1104/pp.102.014720;
RA   Jasinski M., Ducos E., Martinoia E., Boutry M.;
RT   "The ATP-binding cassette transporters: structure, function, and gene
RT   family comparison between rice and Arabidopsis.";
RL   Plant Physiol. 131:1169-1177(2003).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=cv. Nipponbare;
RX   PubMed=12447438; DOI=10.1038/nature01184;
RA   Sasaki T., Matsumoto T., Yamamoto K., Sakata K., Baba T., Katayose Y.,
RA   Wu J., Niimura Y., Cheng Z., Nagamura Y., Antonio B.A., Kanamori H.,
RA   Hosokawa S., Masukawa M., Arikawa K., Chiden Y., Hayashi M., Okamoto M.,
RA   Ando T., Aoki H., Arita K., Hamada M., Harada C., Hijishita S., Honda M.,
RA   Ichikawa Y., Idonuma A., Iijima M., Ikeda M., Ikeno M., Ito S., Ito T.,
RA   Ito Y., Ito Y., Iwabuchi A., Kamiya K., Karasawa W., Katagiri S.,
RA   Kikuta A., Kobayashi N., Kono I., Machita K., Maehara T., Mizuno H.,
RA   Mizubayashi T., Mukai Y., Nagasaki H., Nakashima M., Nakama Y.,
RA   Nakamichi Y., Nakamura M., Namiki N., Negishi M., Ohta I., Ono N., Saji S.,
RA   Sakai K., Shibata M., Shimokawa T., Shomura A., Song J., Takazaki Y.,
RA   Terasawa K., Tsuji K., Waki K., Yamagata H., Yamane H., Yoshiki S.,
RA   Yoshihara R., Yukawa K., Zhong H., Iwama H., Endo T., Ito H., Hahn J.H.,
RA   Kim H.-I., Eun M.-Y., Yano M., Jiang J., Gojobori T.;
RT   "The genome sequence and structure of rice chromosome 1.";
RL   Nature 420:312-316(2002).
RN   [3]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=cv. Nipponbare;
RX   PubMed=16100779; DOI=10.1038/nature03895;
RG   International rice genome sequencing project (IRGSP);
RT   "The map-based sequence of the rice genome.";
RL   Nature 436:793-800(2005).
RN   [4]
RP   GENOME REANNOTATION.
RC   STRAIN=cv. Nipponbare;
RX   PubMed=18089549; DOI=10.1093/nar/gkm978;
RG   The rice annotation project (RAP);
RT   "The rice annotation project database (RAP-DB): 2008 update.";
RL   Nucleic Acids Res. 36:D1028-D1033(2008).
RN   [5]
RP   GENOME REANNOTATION.
RC   STRAIN=cv. Nipponbare;
RX   PubMed=24280374; DOI=10.1186/1939-8433-6-4;
RA   Kawahara Y., de la Bastide M., Hamilton J.P., Kanamori H., McCombie W.R.,
RA   Ouyang S., Schwartz D.C., Tanaka T., Wu J., Zhou S., Childs K.L.,
RA   Davidson R.M., Lin H., Quesada-Ocampo L., Vaillancourt B., Sakai H.,
RA   Lee S.S., Kim J., Numa H., Itoh T., Buell C.R., Matsumoto T.;
RT   "Improvement of the Oryza sativa Nipponbare reference genome using next
RT   generation sequence and optical map data.";
RL   Rice 6:4-4(2013).
RN   [6]
RP   IDENTIFICATION.
RX   PubMed=12430018; DOI=10.1007/s00425-002-0889-z;
RA   van den Brule S., Smart C.C.;
RT   "The plant PDR family of ABC transporters.";
RL   Planta 216:95-106(2002).
RN   [7]
RP   GENE FAMILY, AND NOMENCLATURE.
RX   PubMed=16506311; DOI=10.1016/j.febslet.2005.12.043;
RA   Crouzet J., Trombik T., Fraysse A.S., Boutry M.;
RT   "Organization and function of the plant pleiotropic drug resistance ABC
RT   transporter family.";
RL   FEBS Lett. 580:1123-1130(2006).
RN   [8]
RP   GENE FAMILY, AND NOMENCLATURE.
RX   PubMed=18299247; DOI=10.1016/j.tplants.2008.02.001;
RA   Verrier P.J., Bird D., Burla B., Dassa E., Forestier C., Geisler M.,
RA   Klein M., Kolukisaoglu H.U., Lee Y., Martinoia E., Murphy A., Rea P.A.,
RA   Samuels L., Schulz B., Spalding E.J., Yazaki K., Theodoulou F.L.;
RT   "Plant ABC proteins - a unified nomenclature and updated inventory.";
RL   Trends Plant Sci. 13:151-159(2008).
CC   -!- FUNCTION: May be a general defense protein. {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Membrane {ECO:0000255}; Multi-pass membrane
CC       protein {ECO:0000255}.
CC   -!- SIMILARITY: Belongs to the ABC transporter superfamily. ABCG family.
CC       PDR (TC 3.A.1.205) subfamily. {ECO:0000305}.
CC   -!- SEQUENCE CAUTION:
CC       Sequence=BAF05452.1; Type=Erroneous gene model prediction; Evidence={ECO:0000305};
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DR   EMBL; AJ535044; CAD59566.1; -; Genomic_DNA.
DR   EMBL; AP002844; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; AP008207; BAF05452.1; ALT_SEQ; Genomic_DNA.
DR   EMBL; AP014957; BAS73100.1; -; Genomic_DNA.
DR   EMBL; BK001016; DAA00885.1; -; Genomic_DNA.
DR   RefSeq; XP_015638596.1; XM_015783110.1.
DR   AlphaFoldDB; Q8GU92; -.
DR   SMR; Q8GU92; -.
DR   STRING; 4530.OS01T0609200-00; -.
DR   PaxDb; Q8GU92; -.
DR   PRIDE; Q8GU92; -.
DR   EnsemblPlants; Os01t0609200-00; Os01t0609200-00; Os01g0609200.
DR   GeneID; 4327727; -.
DR   Gramene; Os01t0609200-00; Os01t0609200-00; Os01g0609200.
DR   KEGG; osa:4327727; -.
DR   eggNOG; KOG0065; Eukaryota.
DR   HOGENOM; CLU_000604_35_6_1; -.
DR   InParanoid; Q8GU92; -.
DR   OMA; NGARRCE; -.
DR   OrthoDB; 324553at2759; -.
DR   Proteomes; UP000000763; Chromosome 1.
DR   Proteomes; UP000059680; Chromosome 1.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0140359; F:ABC-type transporter activity; IEA:InterPro.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   CDD; cd03233; ABCG_PDR_domain1; 1.
DR   CDD; cd03232; ABCG_PDR_domain2; 1.
DR   Gene3D; 3.40.50.300; -; 2.
DR   InterPro; IPR003593; AAA+_ATPase.
DR   InterPro; IPR013525; ABC_2_trans.
DR   InterPro; IPR029481; ABC_trans_N.
DR   InterPro; IPR003439; ABC_transporter-like_ATP-bd.
DR   InterPro; IPR043926; ABCG_dom.
DR   InterPro; IPR034001; ABCG_PDR_1.
DR   InterPro; IPR034003; ABCG_PDR_2.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   InterPro; IPR013581; PDR_assoc.
DR   Pfam; PF01061; ABC2_membrane; 2.
DR   Pfam; PF19055; ABC2_membrane_7; 1.
DR   Pfam; PF00005; ABC_tran; 2.
DR   Pfam; PF14510; ABC_trans_N; 1.
DR   Pfam; PF08370; PDR_assoc; 1.
DR   SMART; SM00382; AAA; 2.
DR   SUPFAM; SSF52540; SSF52540; 2.
DR   PROSITE; PS50893; ABC_TRANSPORTER_2; 2.
PE   3: Inferred from homology;
KW   ATP-binding; Membrane; Nucleotide-binding; Reference proteome; Repeat;
KW   Transmembrane; Transmembrane helix; Transport.
FT   CHAIN           1..1464
FT                   /note="ABC transporter G family member 35"
FT                   /id="PRO_0000234644"
FT   TRANSMEM        542..562
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        575..595
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        630..650
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        662..682
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        686..706
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        715..735
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        774..794
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        1213..1233
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        1243..1263
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        1299..1319
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        1326..1346
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        1356..1376
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        1387..1407
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        1436..1456
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   DOMAIN          173..446
FT                   /note="ABC transporter 1"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00434"
FT   DOMAIN          524..737
FT                   /note="ABC transmembrane type-2 1"
FT   DOMAIN          867..1119
FT                   /note="ABC transporter 2"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00434"
FT   DOMAIN          1192..1406
FT                   /note="ABC transmembrane type-2 2"
FT   REGION          1..26
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   BINDING         206..213
FT                   /ligand="ATP"
FT                   /ligand_id="ChEBI:CHEBI:30616"
FT                   /ligand_label="1"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00434"
FT   BINDING         912..919
FT                   /ligand="ATP"
FT                   /ligand_id="ChEBI:CHEBI:30616"
FT                   /ligand_label="2"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00434"
SQ   SEQUENCE   1464 AA;  163870 MW;  C990DB43917B74FF CRC64;
     MDAAAEMQKV VSLRRGGGGS SSRGAASMWW SADNGVFSRS RASSSGEDGE DDEEALRWAA
     LEKLPTYDRV RRAVLPVVEE GGGGGEAGKK VVDVLSLGPQ ERRALLERLV RVAEDDNERF
     LLKLKERIDR VGIDIPTIEV RFEHLEAEAE VRVGNSGLPT VLNSMTNKLE GAANALGILP
     NKKQTMPILH DVSGIVKPRR MTLLLGPPGS GKTTLLLALA GRLGKDIKFS GQVTYNGHQM
     EDFVPQRTAA YISQHDLHIG EMTVRETLSF SARCQGVGSR FDMLTELSRR EKAANIKPDA
     DIDAFMKASA MEGQETNLIT DYILKILGLD ICADTMVGDD MVRGISGGQR KRVTTGEMLV
     GPANALFMDE ISTGLDSSTT FQIVKSLRQA IHILGGTAVI SLLQPAPETY DLFDDIILLS
     DGQIVYQGPR EGVLEFFELM GFKCPERKGV ADFLQEVTSR KDQKQYWMQH DKPYRYVPVK
     DFASAFQSFH TGKSIANELA TPFDKSKNHP AALTTSRYGV SAMELLKANI DREFLLMKRN
     SFVYIFRACQ LMVVSAIAMT VFFRTKMHRD SVTDGVIFMG ALFFSVMMIM FNGLSELPLT
     IFKLPVFFKQ RDLLFFPAWT YTIPSWILKI PMSFIEVGGF VFMSYYVIGF DPSAGRFFKQ
     YLLMLAINQM AAALFRFVGG AARNMIVANV FGSFMLLIFM VLGGFILVRE KVKKWWIWGY
     WISPMMYAQN AISVNEFLGH SWDKVLNNSL SNETLGVQAL RSRGVFPEAK WYWIGFGALL
     GFIMLFNGLF TLALTYLKPY GKSQPSVSEE ELKEKQANIN GNVLDVDTMA SSTNLAIVDN
     TETSSEIADN SQPTQRGMVL PFAPLSLTFD NIKYSVDMPQ EMKAHGIVED RLELLKGVSG
     SFRPGVLTAL MGVSGAGKTT LMDVLAGRKT GGYIEGNITI SGYPKKQETF ARVSGYCEQN
     DIHSPQVTVS ESLLFSAWLR LPKDVDSNTR KMFIEEVMEL VELKPLRDAL VGLPGVNGLS
     TEQRKRLTIA VELVANPSII FMDEPTSGLD ARAAAIVMRT VRNTVDTGRT VVCTIHQPSI
     DIFEAFDELF LMKRGGEEIY VGPLGHQSSE LIKYFEGIKG VSRIKDGYNP ATWMLEVSTI
     SQEQALGVDF CDIYRKSELF QRNKALIQEL STPPPGSSEL YFPTKYSLSF LNQCLACLWK
     MHLSYWRNPP YNAIRLFFTT VIALLFGTIF WDLGGKTGKS QDLFNAMGSM YSAVLFIGVL
     NSQSVQPVVS VERTVFYRER AAGMYSAFPY AFGQVAIEFP YTLVQSIIYG IIVYSMIGFK
     WTAAKFFWYL FFMFFTFLYF TFYGMMAVGL TPSYHVASIV SSAFYGIWNL FSGFIIPRPK
     VPIWWRWYCW ICPVAWTLYG LVASQFGDIM TPMDDGTPVK IFVENYFDFK HSWLGVVAVV
     IVAFTMLFAF LFGFAIMKLN FQKR