AB37G_ORYSJ
ID AB37G_ORYSJ Reviewed; 1450 AA.
AC Q8GU89; Q0JLC3; Q5ZE25;
DT 16-MAY-2006, integrated into UniProtKB/Swiss-Prot.
DT 01-MAR-2003, sequence version 1.
DT 03-AUG-2022, entry version 114.
DE RecName: Full=ABC transporter G family member 37 {ECO:0000303|PubMed:18299247};
DE Short=OsABCG37 {ECO:0000303|PubMed:18299247};
DE AltName: Full=Pleiotropic drug resistance protein 8 {ECO:0000303|PubMed:12644668, ECO:0000303|PubMed:16506311};
DE Short=OsPDR8 {ECO:0000303|PubMed:16506311};
GN Name=ABCG37 {ECO:0000303|PubMed:18299247};
GN Synonyms=PDR4 {ECO:0000303|PubMed:12430018},
GN PDR8 {ECO:0000303|PubMed:12644668, ECO:0000303|PubMed:16506311};
GN OrderedLocusNames=Os01g0609900 {ECO:0000312|EMBL:BAF05455.1},
GN LOC_Os01g42410; ORFNames=P0410E03.10 {ECO:0000312|EMBL:BAD52527.1};
OS Oryza sativa subsp. japonica (Rice).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; Liliopsida; Poales; Poaceae; BOP clade;
OC Oryzoideae; Oryzeae; Oryzinae; Oryza; Oryza sativa.
OX NCBI_TaxID=39947;
RN [1]
RP NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC STRAIN=cv. Nipponbare;
RX PubMed=12644668; DOI=10.1104/pp.102.014720;
RA Jasinski M., Ducos E., Martinoia E., Boutry M.;
RT "The ATP-binding cassette transporters: structure, function, and gene
RT family comparison between rice and Arabidopsis.";
RL Plant Physiol. 131:1169-1177(2003).
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Nipponbare;
RX PubMed=12447438; DOI=10.1038/nature01184;
RA Sasaki T., Matsumoto T., Yamamoto K., Sakata K., Baba T., Katayose Y.,
RA Wu J., Niimura Y., Cheng Z., Nagamura Y., Antonio B.A., Kanamori H.,
RA Hosokawa S., Masukawa M., Arikawa K., Chiden Y., Hayashi M., Okamoto M.,
RA Ando T., Aoki H., Arita K., Hamada M., Harada C., Hijishita S., Honda M.,
RA Ichikawa Y., Idonuma A., Iijima M., Ikeda M., Ikeno M., Ito S., Ito T.,
RA Ito Y., Ito Y., Iwabuchi A., Kamiya K., Karasawa W., Katagiri S.,
RA Kikuta A., Kobayashi N., Kono I., Machita K., Maehara T., Mizuno H.,
RA Mizubayashi T., Mukai Y., Nagasaki H., Nakashima M., Nakama Y.,
RA Nakamichi Y., Nakamura M., Namiki N., Negishi M., Ohta I., Ono N., Saji S.,
RA Sakai K., Shibata M., Shimokawa T., Shomura A., Song J., Takazaki Y.,
RA Terasawa K., Tsuji K., Waki K., Yamagata H., Yamane H., Yoshiki S.,
RA Yoshihara R., Yukawa K., Zhong H., Iwama H., Endo T., Ito H., Hahn J.H.,
RA Kim H.-I., Eun M.-Y., Yano M., Jiang J., Gojobori T.;
RT "The genome sequence and structure of rice chromosome 1.";
RL Nature 420:312-316(2002).
RN [3]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Nipponbare;
RX PubMed=16100779; DOI=10.1038/nature03895;
RG International rice genome sequencing project (IRGSP);
RT "The map-based sequence of the rice genome.";
RL Nature 436:793-800(2005).
RN [4]
RP GENOME REANNOTATION.
RC STRAIN=cv. Nipponbare;
RX PubMed=18089549; DOI=10.1093/nar/gkm978;
RG The rice annotation project (RAP);
RT "The rice annotation project database (RAP-DB): 2008 update.";
RL Nucleic Acids Res. 36:D1028-D1033(2008).
RN [5]
RP GENOME REANNOTATION.
RC STRAIN=cv. Nipponbare;
RX PubMed=24280374; DOI=10.1186/1939-8433-6-4;
RA Kawahara Y., de la Bastide M., Hamilton J.P., Kanamori H., McCombie W.R.,
RA Ouyang S., Schwartz D.C., Tanaka T., Wu J., Zhou S., Childs K.L.,
RA Davidson R.M., Lin H., Quesada-Ocampo L., Vaillancourt B., Sakai H.,
RA Lee S.S., Kim J., Numa H., Itoh T., Buell C.R., Matsumoto T.;
RT "Improvement of the Oryza sativa Nipponbare reference genome using next
RT generation sequence and optical map data.";
RL Rice 6:4-4(2013).
RN [6]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] OF 62-1450.
RC STRAIN=cv. Nipponbare;
RX PubMed=12869764; DOI=10.1126/science.1081288;
RG The rice full-length cDNA consortium;
RT "Collection, mapping, and annotation of over 28,000 cDNA clones from
RT japonica rice.";
RL Science 301:376-379(2003).
RN [7]
RP IDENTIFICATION.
RX PubMed=12430018; DOI=10.1007/s00425-002-0889-z;
RA van den Brule S., Smart C.C.;
RT "The plant PDR family of ABC transporters.";
RL Planta 216:95-106(2002).
RN [8]
RP GENE FAMILY, AND NOMENCLATURE.
RX PubMed=16506311; DOI=10.1016/j.febslet.2005.12.043;
RA Crouzet J., Trombik T., Fraysse A.S., Boutry M.;
RT "Organization and function of the plant pleiotropic drug resistance ABC
RT transporter family.";
RL FEBS Lett. 580:1123-1130(2006).
RN [9]
RP GENE FAMILY, AND NOMENCLATURE.
RX PubMed=18299247; DOI=10.1016/j.tplants.2008.02.001;
RA Verrier P.J., Bird D., Burla B., Dassa E., Forestier C., Geisler M.,
RA Klein M., Kolukisaoglu H.U., Lee Y., Martinoia E., Murphy A., Rea P.A.,
RA Samuels L., Schulz B., Spalding E.J., Yazaki K., Theodoulou F.L.;
RT "Plant ABC proteins - a unified nomenclature and updated inventory.";
RL Trends Plant Sci. 13:151-159(2008).
CC -!- FUNCTION: May be a general defense protein. {ECO:0000250}.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000255}; Multi-pass membrane
CC protein {ECO:0000255}.
CC -!- SIMILARITY: Belongs to the ABC transporter superfamily. ABCG family.
CC PDR (TC 3.A.1.205) subfamily. {ECO:0000305}.
CC -!- SEQUENCE CAUTION:
CC Sequence=BAD52527.1; Type=Erroneous initiation; Note=Truncated N-terminus.; Evidence={ECO:0000305};
CC Sequence=BAF05455.1; Type=Erroneous gene model prediction; Evidence={ECO:0000305};
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DR EMBL; AJ535047; CAD59569.1; -; Genomic_DNA.
DR EMBL; AP002844; BAD52527.1; ALT_INIT; Genomic_DNA.
DR EMBL; AP008207; BAF05455.1; ALT_SEQ; Genomic_DNA.
DR EMBL; AP014957; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AK065988; -; NOT_ANNOTATED_CDS; mRNA.
DR EMBL; BK001018; DAA00887.1; -; Genomic_DNA.
DR RefSeq; XP_015648329.1; XM_015792843.1.
DR AlphaFoldDB; Q8GU89; -.
DR SMR; Q8GU89; -.
DR STRING; 4530.OS01T0609900-02; -.
DR PaxDb; Q8GU89; -.
DR PRIDE; Q8GU89; -.
DR GeneID; 4327730; -.
DR KEGG; osa:4327730; -.
DR eggNOG; KOG0065; Eukaryota.
DR InParanoid; Q8GU89; -.
DR OrthoDB; 324553at2759; -.
DR Proteomes; UP000000763; Chromosome 1.
DR Proteomes; UP000059680; Chromosome 1.
DR Genevisible; Q8GU89; OS.
DR GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR GO; GO:0140359; F:ABC-type transporter activity; IEA:InterPro.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR CDD; cd03233; ABCG_PDR_domain1; 1.
DR CDD; cd03232; ABCG_PDR_domain2; 1.
DR Gene3D; 3.40.50.300; -; 2.
DR InterPro; IPR003593; AAA+_ATPase.
DR InterPro; IPR013525; ABC_2_trans.
DR InterPro; IPR029481; ABC_trans_N.
DR InterPro; IPR003439; ABC_transporter-like_ATP-bd.
DR InterPro; IPR043926; ABCG_dom.
DR InterPro; IPR034001; ABCG_PDR_1.
DR InterPro; IPR034003; ABCG_PDR_2.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR013581; PDR_assoc.
DR Pfam; PF01061; ABC2_membrane; 2.
DR Pfam; PF19055; ABC2_membrane_7; 2.
DR Pfam; PF00005; ABC_tran; 2.
DR Pfam; PF14510; ABC_trans_N; 1.
DR Pfam; PF08370; PDR_assoc; 1.
DR SMART; SM00382; AAA; 2.
DR SUPFAM; SSF52540; SSF52540; 2.
DR PROSITE; PS50893; ABC_TRANSPORTER_2; 2.
PE 2: Evidence at transcript level;
KW ATP-binding; Membrane; Nucleotide-binding; Reference proteome; Repeat;
KW Transmembrane; Transmembrane helix; Transport.
FT CHAIN 1..1450
FT /note="ABC transporter G family member 37"
FT /id="PRO_0000234646"
FT TRANSMEM 527..547
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 559..579
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 614..634
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 646..666
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 670..690
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 756..776
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 1198..1218
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 1236..1256
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 1284..1304
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 1311..1331
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 1341..1361
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 1372..1392
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 1422..1442
FT /note="Helical"
FT /evidence="ECO:0000255"
FT DOMAIN 158..431
FT /note="ABC transporter 1"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00434"
FT DOMAIN 509..721
FT /note="ABC transmembrane type-2 1"
FT DOMAIN 852..1104
FT /note="ABC transporter 2"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00434"
FT DOMAIN 1177..1391
FT /note="ABC transmembrane type-2 2"
FT BINDING 191..198
FT /ligand="ATP"
FT /ligand_id="ChEBI:CHEBI:30616"
FT /ligand_label="1"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00434"
FT BINDING 897..904
FT /ligand="ATP"
FT /ligand_id="ChEBI:CHEBI:30616"
FT /ligand_label="2"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00434"
FT CONFLICT 940
FT /note="G -> R (in Ref. 6; AK065988)"
FT /evidence="ECO:0000305"
FT CONFLICT 1331
FT /note="M -> T (in Ref. 6; AK065988)"
FT /evidence="ECO:0000305"
SQ SEQUENCE 1450 AA; 163421 MW; D7C9837D02A82609 CRC64;
MDREVHRMAS LRREGSMWRS GGDVFSRSSS RFQDEDDDEE ALRWAALERL PTYDRVRRGI
LAVSSEDGGA GGEKVEVDVG RLGARESRAL IERLVRAADD DHERFLLKLR ERMDRVGIDY
PTIEVRFENL EVEADVHVGN RGLPTLLNSV TNTVEAIGNA LHILPNKKQP MTVLHDVSGI
IKPRRMTLLL GPPGSGKTTL LLALAGKLDK DLKVSGKVTY NGHGMHEFVP ERTAAYISQH
DLHIGEMTVR ETLAFSARCQ GVGTRYEMLT ELARREKAAN IKPDHDIDIY MKASAMGGQE
SSVVTDYILK ILGLDICADT VVGNEMLRGI SGGQRKRVTT GEMLVGPARA LFMDEISTGL
DSSTTYQIVN SLRQTIHILG GTAVISLLQP APETYNLFDD IILLSDGQVV YQGPREHVLE
FFEFMGFRCP ARKGVADFLQ EVTSRKDQGQ YWCRRDRPYR FVPVKQFADA FRSFHVGRSI
QNELSEPFDR TRSHPAALAT SKYGVSRKEL LKATIDRELL LMKRNAFMYI FKAVNLTLMA
LIVMTTFFRT SMRHDRDYGM IYLGALYFAL DTVMFNGFAE LAMTVMKLPV FFKQRDLLFF
PAWAYTIPSW ILQIPITFLE VGVYVFITYY VIGFDPSVSR FFKQYLLLLA LNQMSSALFR
FIAGIGRDMV VSHTFGPLSL LAFAALGGFI LARPDVKKWW IWGYWISPLS YAQNAISTNE
FLGHSWSQIL PGENVTLGVS VLKSRGIFTE AKWYWIGLGA LLGYTLLFNL LYTVALSVLS
PFTDSHASMS EDALKEKHAN LTGEVVEGQK DTKSRKQELE LSHIADQNSG INSADSSASR
KGMVLPFAPL SISFNDVRYS VDMPEAMKAQ GITEDRLLLL KGVSGSFRPG VLTALMGVSG
AGKTTLMDVL AGRKTGGYIE GDIRISGYPK KQETFARISG YCEQNDIHSP HVTVYESLVF
SAWLRLPSEV DSEARKMFIE EVMDLVELTS LRGALVGLPG VSGLSTEQRK RLTIAVELVA
NPSIIFMDEP TSGLDARAAA IVMRTVRNTV NTGRTVVCTI HQPSIDIFEA FDELFLMKRG
GEEIYVGPVG QNSSKLIEYF EGIDGVSRIK DGYNPATWML EVTSSAQEEM LGVDFSEIYR
QSELYQRNKE LIEELSTPPP GSTDLNFPTQ YSRSFITQCL ACLWKQNWSY WRNPSYTAVR
LLFTIVIALM FGTMFWNLGT RTKKQQDLFN AMGSMYAAVL YIGVQNSGSV QPVVVVERTV
FYRERAAGMY SAFPYAFGQV AIELPYIMVQ TLIYGVLVYS MIGFEWTVAK FLWYLFFMYF
TLLYFTFYGM MAVGLTPNES IAAIISSAFY NVWNLFSGYL IPRPKIPVWW RWYCWICPVA
WTLYGLVASQ FGDIQHVLEG DTRTVAQFVT DYFGFHHNFL WVVAVVHVVF AVTFAFLFSF
AIMKFNFQRR
