ID   RPOB_ACIAD              Reviewed;        1362 AA.
AC   Q6FF90;
DT   21-FEB-2006, integrated into UniProtKB/Swiss-Prot.
DT   19-JUL-2004, sequence version 1.
DT   03-AUG-2022, entry version 112.
DE   RecName: Full=DNA-directed RNA polymerase subunit beta {ECO:0000255|HAMAP-Rule:MF_01321};
DE            Short=RNAP subunit beta {ECO:0000255|HAMAP-Rule:MF_01321};
DE            EC=2.7.7.6 {ECO:0000255|HAMAP-Rule:MF_01321};
DE   AltName: Full=RNA polymerase subunit beta {ECO:0000255|HAMAP-Rule:MF_01321};
DE   AltName: Full=Transcriptase subunit beta {ECO:0000255|HAMAP-Rule:MF_01321};
GN   Name=rpoB {ECO:0000255|HAMAP-Rule:MF_01321}; OrderedLocusNames=ACIAD0307;
OS   Acinetobacter baylyi (strain ATCC 33305 / BD413 / ADP1).
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Moraxellales; Moraxellaceae;
OC   Acinetobacter.
OX   NCBI_TaxID=62977;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 33305 / BD413 / ADP1;
RX   PubMed=15514110; DOI=10.1093/nar/gkh910;
RA   Barbe V., Vallenet D., Fonknechten N., Kreimeyer A., Oztas S., Labarre L.,
RA   Cruveiller S., Robert C., Duprat S., Wincker P., Ornston L.N.,
RA   Weissenbach J., Marliere P., Cohen G.N., Medigue C.;
RT   "Unique features revealed by the genome sequence of Acinetobacter sp. ADP1,
RT   a versatile and naturally transformation competent bacterium.";
RL   Nucleic Acids Res. 32:5766-5779(2004).
CC   -!- FUNCTION: DNA-dependent RNA polymerase catalyzes the transcription of
CC       DNA into RNA using the four ribonucleoside triphosphates as substrates.
CC       {ECO:0000255|HAMAP-Rule:MF_01321}.
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=a ribonucleoside 5'-triphosphate + RNA(n) = diphosphate +
CC         RNA(n+1); Xref=Rhea:RHEA:21248, Rhea:RHEA-COMP:14527, Rhea:RHEA-
CC         COMP:17342, ChEBI:CHEBI:33019, ChEBI:CHEBI:61557, ChEBI:CHEBI:140395;
CC         EC=2.7.7.6; Evidence={ECO:0000255|HAMAP-Rule:MF_01321};
CC   -!- SUBUNIT: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta'
CC       and 1 omega subunit. When a sigma factor is associated with the core
CC       the holoenzyme is formed, which can initiate transcription.
CC       {ECO:0000255|HAMAP-Rule:MF_01321}.
CC   -!- SIMILARITY: Belongs to the RNA polymerase beta chain family.
CC       {ECO:0000255|HAMAP-Rule:MF_01321}.
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DR   EMBL; CR543861; CAG67267.1; -; Genomic_DNA.
DR   RefSeq; WP_011182019.1; NC_005966.1.
DR   AlphaFoldDB; Q6FF90; -.
DR   SMR; Q6FF90; -.
DR   STRING; 62977.ACIAD0307; -.
DR   PRIDE; Q6FF90; -.
DR   EnsemblBacteria; CAG67267; CAG67267; ACIAD0307.
DR   GeneID; 45232821; -.
DR   KEGG; aci:ACIAD0307; -.
DR   eggNOG; COG0085; Bacteria.
DR   HOGENOM; CLU_000524_4_0_6; -.
DR   OMA; FMTWEGY; -.
DR   OrthoDB; 9601at2; -.
DR   BioCyc; ASP62977:ACIAD_RS01460-MON; -.
DR   Proteomes; UP000000430; Chromosome.
DR   GO; GO:0000428; C:DNA-directed RNA polymerase complex; IEA:UniProtKB-KW.
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-UniRule.
DR   GO; GO:0003899; F:DNA-directed 5'-3' RNA polymerase activity; IEA:UniProtKB-UniRule.
DR   GO; GO:0032549; F:ribonucleoside binding; IEA:InterPro.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-UniRule.
DR   CDD; cd00653; RNA_pol_B_RPB2; 1.
DR   Gene3D; 2.30.150.10; -; 1.
DR   Gene3D; 2.40.270.10; -; 2.
DR   Gene3D; 2.40.50.150; -; 1.
DR   Gene3D; 3.90.1110.10; -; 2.
DR   HAMAP; MF_01321; RNApol_bact_RpoB; 1.
DR   InterPro; IPR042107; DNA-dir_RNA_pol_bsu_ext_1_sf.
DR   InterPro; IPR019462; DNA-dir_RNA_pol_bsu_external_1.
DR   InterPro; IPR015712; DNA-dir_RNA_pol_su2.
DR   InterPro; IPR007120; DNA-dir_RNAP_su2_dom.
DR   InterPro; IPR037033; DNA-dir_RNAP_su2_hyb_sf.
DR   InterPro; IPR010243; RNA_pol_bsu_bac.
DR   InterPro; IPR007121; RNA_pol_bsu_CS.
DR   InterPro; IPR007644; RNA_pol_bsu_protrusion.
DR   InterPro; IPR007642; RNA_pol_Rpb2_2.
DR   InterPro; IPR037034; RNA_pol_Rpb2_2_sf.
DR   InterPro; IPR007645; RNA_pol_Rpb2_3.
DR   InterPro; IPR007641; RNA_pol_Rpb2_7.
DR   InterPro; IPR014724; RNA_pol_RPB2_OB-fold.
DR   PANTHER; PTHR20856; PTHR20856; 1.
DR   Pfam; PF04563; RNA_pol_Rpb2_1; 1.
DR   Pfam; PF04561; RNA_pol_Rpb2_2; 2.
DR   Pfam; PF04565; RNA_pol_Rpb2_3; 1.
DR   Pfam; PF10385; RNA_pol_Rpb2_45; 1.
DR   Pfam; PF00562; RNA_pol_Rpb2_6; 1.
DR   Pfam; PF04560; RNA_pol_Rpb2_7; 1.
DR   TIGRFAMs; TIGR02013; rpoB; 1.
DR   PROSITE; PS01166; RNA_POL_BETA; 1.
PE   3: Inferred from homology;
KW   DNA-directed RNA polymerase; Nucleotidyltransferase; Reference proteome;
KW   Transcription; Transferase.
FT   CHAIN           1..1362
FT                   /note="DNA-directed RNA polymerase subunit beta"
FT                   /id="PRO_0000224022"
SQ   SEQUENCE   1362 AA;  151484 MW;  840F7A54A31DA85B CRC64;
     MAYSYTEKKR IRKNFGKLPS VMDAPYLLSI QVDSYRTFLQ DGKSPKNRED IGLQAAFRSV
     FPIESYSGNA ALEFVEYGLG KPEFDVRECI LRGSTYAAPM RVKIRLIIKD RETKSIKDVR
     EQEVYMGEIP LMTENGTFVI NGTERVIVSQ LHRSPGVFFD HDKGKTHSSG KVLYSARIIP
     YRGSWLDFEF DAKDLVYVRI DRRRKLLASV ILRALGYNNA QILDLFYEKV PVYLDFGSYQ
     IDLVPERLRG EMAQFDIADN DGKVIVEQGK RINARHVRQM EASGLTKLSV PDEYLYERIT
     AEDITLRDGD VIAANTLLSH EIMVKLAEGG VKQFNILYTN DIDHGSFVAD TLRADTTMGR
     EDALVEIYKV MRPGEPPTKE AAENLFNNLF FSSERYDLSP VGRMKFNRRL GRPYEVGTDQ
     KSREVEGILS NEDIIDVLRT LVEIRNGKGE VDDIDHLGNR RVRSVGEMTE NQFRVGLVRV
     ERAVKERLSQ AETDNLSPQD LINAKPVAAA IKEFFGSSQL SQFMDQNNPL SEITHKRRVS
     ALGPGGLTRE RAGFEVRDVH QTHYGRVCPI ETPEGPNIGL INSLSVYAKA NDFGFLETPY
     RKVVDGRVSD DVEYLSAIEE VGTVIAQADS AVDADGHLME EMVSVRHQGE FVRMPPEKVT
     HMDVSAQQVV SVAASLIPFL EHDDANRALM GSNMQRQAVP TLLADKPLVG TGMEANVARD
     SGVCVIAKRG GMIEFVDASR VVIRVNEEEM IAGEAGVDIY NLIKYTRSNQ NTCINQKVLV
     NLGDKVGRGD VLADGPSTDG GELALGQNMR VAFMTWNGYN YEDSILLSER VLQEDRLTSI
     HIQELSCVAR DTKLGAEEIT ADIPNVGEAA LSKLDESGIV YIGAEVTAGD ILVGKVTPKG
     ETQLTPEEKL LRAIFGEKAA DVKDSSLRVP SGTKGTVIDV QVFTRDGLEK DDRALAIEKA
     QLDAYRKDLK EEYKIFEEAA RERIVRLLNG QESNGGGTTK RGDKLSDDVL SGLELVDLLD
     IQPTDEGIAE RLSQIQVFLK EKSAEIDEKF AEKKRKLATG DELTTGVLKV VKVYLAVKRR
     IQPGDKMAGR HGNKGVVSNI LPVEDMPHDA NGVPVDVVLN PLGVPSRMNV GQILETHLGL
     AAKGLGEQID KMLQQQRTIA ELRIFLDKIY NKVGGEQEEL DTLTDEEILV LAGNLRKGVP
     LATPVFDGAE EGQIKELLEL AELPRTGQQI LFDGRTGEQF DRPVTVGYMY MLKLNHLVDD
     KMHARSTGSY SLVTQQPLGG KAQFGGQRFG EMEVWALEAY GAAYTLQEML TVKSDDVEGR
     TRIYKNIVDG NHYMDPGMPE SFNVLTKEIR SLGINIELKN GD