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RPOB_ACIBS
ID   RPOB_ACIBS              Reviewed;        1362 AA.
AC   B0VLZ6;
DT   14-APR-2009, integrated into UniProtKB/Swiss-Prot.
DT   08-APR-2008, sequence version 1.
DT   03-AUG-2022, entry version 88.
DE   RecName: Full=DNA-directed RNA polymerase subunit beta {ECO:0000255|HAMAP-Rule:MF_01321};
DE            Short=RNAP subunit beta {ECO:0000255|HAMAP-Rule:MF_01321};
DE            EC=2.7.7.6 {ECO:0000255|HAMAP-Rule:MF_01321};
DE   AltName: Full=RNA polymerase subunit beta {ECO:0000255|HAMAP-Rule:MF_01321};
DE   AltName: Full=Transcriptase subunit beta {ECO:0000255|HAMAP-Rule:MF_01321};
GN   Name=rpoB {ECO:0000255|HAMAP-Rule:MF_01321}; OrderedLocusNames=ABSDF3243;
OS   Acinetobacter baumannii (strain SDF).
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Moraxellales; Moraxellaceae;
OC   Acinetobacter; Acinetobacter calcoaceticus/baumannii complex.
OX   NCBI_TaxID=509170;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=SDF;
RX   PubMed=18350144; DOI=10.1371/journal.pone.0001805;
RA   Vallenet D., Nordmann P., Barbe V., Poirel L., Mangenot S., Bataille E.,
RA   Dossat C., Gas S., Kreimeyer A., Lenoble P., Oztas S., Poulain J.,
RA   Segurens B., Robert C., Abergel C., Claverie J.-M., Raoult D., Medigue C.,
RA   Weissenbach J., Cruveiller S.;
RT   "Comparative analysis of Acinetobacters: three genomes for three
RT   lifestyles.";
RL   PLoS ONE 3:E1805-E1805(2008).
CC   -!- FUNCTION: DNA-dependent RNA polymerase catalyzes the transcription of
CC       DNA into RNA using the four ribonucleoside triphosphates as substrates.
CC       {ECO:0000255|HAMAP-Rule:MF_01321}.
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=a ribonucleoside 5'-triphosphate + RNA(n) = diphosphate +
CC         RNA(n+1); Xref=Rhea:RHEA:21248, Rhea:RHEA-COMP:14527, Rhea:RHEA-
CC         COMP:17342, ChEBI:CHEBI:33019, ChEBI:CHEBI:61557, ChEBI:CHEBI:140395;
CC         EC=2.7.7.6; Evidence={ECO:0000255|HAMAP-Rule:MF_01321};
CC   -!- SUBUNIT: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta'
CC       and 1 omega subunit. When a sigma factor is associated with the core
CC       the holoenzyme is formed, which can initiate transcription.
CC       {ECO:0000255|HAMAP-Rule:MF_01321}.
CC   -!- SIMILARITY: Belongs to the RNA polymerase beta chain family.
CC       {ECO:0000255|HAMAP-Rule:MF_01321}.
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DR   EMBL; CU468230; CAP02513.1; -; Genomic_DNA.
DR   AlphaFoldDB; B0VLZ6; -.
DR   SMR; B0VLZ6; -.
DR   EnsemblBacteria; CAP02513; CAP02513; ABSDF3243.
DR   KEGG; abm:ABSDF3243; -.
DR   HOGENOM; CLU_000524_4_3_6; -.
DR   OMA; FMTWEGY; -.
DR   Proteomes; UP000001741; Chromosome.
DR   GO; GO:0000428; C:DNA-directed RNA polymerase complex; IEA:UniProtKB-KW.
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-UniRule.
DR   GO; GO:0003899; F:DNA-directed 5'-3' RNA polymerase activity; IEA:UniProtKB-UniRule.
DR   GO; GO:0032549; F:ribonucleoside binding; IEA:InterPro.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-UniRule.
DR   CDD; cd00653; RNA_pol_B_RPB2; 1.
DR   Gene3D; 2.30.150.10; -; 1.
DR   Gene3D; 2.40.270.10; -; 2.
DR   Gene3D; 2.40.50.150; -; 1.
DR   Gene3D; 3.90.1110.10; -; 2.
DR   HAMAP; MF_01321; RNApol_bact_RpoB; 1.
DR   InterPro; IPR042107; DNA-dir_RNA_pol_bsu_ext_1_sf.
DR   InterPro; IPR019462; DNA-dir_RNA_pol_bsu_external_1.
DR   InterPro; IPR015712; DNA-dir_RNA_pol_su2.
DR   InterPro; IPR007120; DNA-dir_RNAP_su2_dom.
DR   InterPro; IPR037033; DNA-dir_RNAP_su2_hyb_sf.
DR   InterPro; IPR010243; RNA_pol_bsu_bac.
DR   InterPro; IPR007121; RNA_pol_bsu_CS.
DR   InterPro; IPR007644; RNA_pol_bsu_protrusion.
DR   InterPro; IPR007642; RNA_pol_Rpb2_2.
DR   InterPro; IPR037034; RNA_pol_Rpb2_2_sf.
DR   InterPro; IPR007645; RNA_pol_Rpb2_3.
DR   InterPro; IPR007641; RNA_pol_Rpb2_7.
DR   InterPro; IPR014724; RNA_pol_RPB2_OB-fold.
DR   PANTHER; PTHR20856; PTHR20856; 1.
DR   Pfam; PF04563; RNA_pol_Rpb2_1; 1.
DR   Pfam; PF04561; RNA_pol_Rpb2_2; 2.
DR   Pfam; PF04565; RNA_pol_Rpb2_3; 1.
DR   Pfam; PF10385; RNA_pol_Rpb2_45; 1.
DR   Pfam; PF00562; RNA_pol_Rpb2_6; 1.
DR   Pfam; PF04560; RNA_pol_Rpb2_7; 1.
DR   TIGRFAMs; TIGR02013; rpoB; 1.
DR   PROSITE; PS01166; RNA_POL_BETA; 1.
PE   3: Inferred from homology;
KW   DNA-directed RNA polymerase; Nucleotidyltransferase; Transcription;
KW   Transferase.
FT   CHAIN           1..1362
FT                   /note="DNA-directed RNA polymerase subunit beta"
FT                   /id="PRO_1000141650"
SQ   SEQUENCE   1362 AA;  151865 MW;  F848BE9E28F7DEE4 CRC64;
     MAYSYTEKKR IRKNFGKLPQ VMDAPYLLSI QVDSYRTFLQ DGKSPKNRED IGLQAAFRSV
     FPIESYSGNA ALEFVEYSLG KPEFDVRECI LRGSTYAAPM RVKIRLIIKD RETKSIKDVR
     EQEVYMGEIP LMTENGTFVI NGTERVIVSQ LHRSPGVFFD HDKGKTHSSG KVLYSARIIP
     YRGSWLDFEF DAKDLVYVRI DRRRKLLATV VLRALGYNNE QILNLFYEKL PVYLDMGSYQ
     IDLVPERLRG EMAQFDITDN EGKVIVEQGK RINARHVRQM EAAGLTKLSV PDEYLYERIT
     AEDITLRDGE VIAANTLLSH EVMVKLAEGG VKQFNILFTN DIDRGSFVAD TLRADLTRDR
     EEALVEIYKV MRPGEPPTKE AAENLFNNLF FSSERYDLSP VGRMKFNRRL GRPYEVGTDQ
     KSREVEGILS HEDIIDVLRT LVEIRNGKGE VDDIDHLGNR RVRSVGEMTE NQFRVGLVRV
     ERAVKERLSQ AETDNLSPQD LINAKPVAAA IKEFFGSSQL SQFMDQNNPL SEITHKRRVS
     ALGPGGLTRE RAGFEVRDVH QTHYGRVCPI ETPEGPNIGL INSLSVYAKA NDFGFLETPY
     RKVVDGRVTD DVEYLSAIEE VGTVIAQADS AVDKDGNLTE EFVSVRHQGE FVRMPPEKVT
     HMDVSAQQVV SVAASLIPFL EHDDANRALM GSNMQRQAVP TLRADKPLVG TGMEANVARD
     SGVCVIANRG GVIEYVDASR IVIRVNEDEM VAGEAGVDIY NLIKYTRSNQ NTCINQNVIV
     NLGDKVARGD ILADGPSTDM GELALGQNMR VAFMTWNGYN YEDSILLSER VLQEDRLTSI
     HIQELSCVAR DTKLGAEEIT ADIPNVGEAA LSKLDESGIV YIGAEVTAGD ILVGKVTPKG
     ETQLTPEEKL LRAIFGEKAA DVKDSSLRVP SGTKGTVIDV QVFTRDGLEK DDRALAIEKA
     QLDSYRKDLK EEYKIFEEAA RERVIRLLKG QESNGGGSTK RGDKLSEDLL SGLELVDLLE
     IQPADEAIAE RLTQIQVFLK EKSAEIDEKF AEKKRKLATG DELTTGVLKV VKVYLAVKRR
     IQPGDKMAGR HGNKGVVSNI LPVEDMPHDA NGVPVDIVLN PLGVPSRMNV GQILETHLGM
     AAKGLGDKIE KMLKEQRTVL ELREFLDKIY NKVGGEQEDL DSLTDEEILA LAGNLRAGVP
     LATPVFDGAE ESQIKDLLEL ADISRTGQTV LFDGRTGEQF DRPVTVGYMY MLKLNHLVDD
     KMHARSTGSY SLVTQQPLGG KAQFGGQRFG EMEVWALEAY GAAYTLQEML TVKSDDVEGR
     TRIYKNIVDG NHYMDPGMPE SFNVLTKEIR SLGINIELKN GD
 
 
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