RPOB_ACICJ
ID RPOB_ACICJ Reviewed; 1400 AA.
AC A5FZX1;
DT 15-JAN-2008, integrated into UniProtKB/Swiss-Prot.
DT 12-JUN-2007, sequence version 1.
DT 03-AUG-2022, entry version 76.
DE RecName: Full=DNA-directed RNA polymerase subunit beta {ECO:0000255|HAMAP-Rule:MF_01321};
DE Short=RNAP subunit beta {ECO:0000255|HAMAP-Rule:MF_01321};
DE EC=2.7.7.6 {ECO:0000255|HAMAP-Rule:MF_01321};
DE AltName: Full=RNA polymerase subunit beta {ECO:0000255|HAMAP-Rule:MF_01321};
DE AltName: Full=Transcriptase subunit beta {ECO:0000255|HAMAP-Rule:MF_01321};
GN Name=rpoB {ECO:0000255|HAMAP-Rule:MF_01321}; OrderedLocusNames=Acry_1952;
OS Acidiphilium cryptum (strain JF-5).
OC Bacteria; Proteobacteria; Alphaproteobacteria; Rhodospirillales;
OC Acetobacteraceae; Acidiphilium.
OX NCBI_TaxID=349163;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=JF-5;
RG US DOE Joint Genome Institute;
RA Copeland A., Lucas S., Lapidus A., Barry K., Detter J.C.,
RA Glavina del Rio T., Hammon N., Israni S., Dalin E., Tice H., Pitluck S.,
RA Sims D., Brettin T., Bruce D., Han C., Schmutz J., Larimer F., Land M.,
RA Hauser L., Kyrpides N., Kim E., Magnuson T., Richardson P.;
RT "Complete sequence of chromosome of Acidiphilium cryptum JF-5.";
RL Submitted (MAY-2007) to the EMBL/GenBank/DDBJ databases.
CC -!- FUNCTION: DNA-dependent RNA polymerase catalyzes the transcription of
CC DNA into RNA using the four ribonucleoside triphosphates as substrates.
CC {ECO:0000255|HAMAP-Rule:MF_01321}.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=a ribonucleoside 5'-triphosphate + RNA(n) = diphosphate +
CC RNA(n+1); Xref=Rhea:RHEA:21248, Rhea:RHEA-COMP:14527, Rhea:RHEA-
CC COMP:17342, ChEBI:CHEBI:33019, ChEBI:CHEBI:61557, ChEBI:CHEBI:140395;
CC EC=2.7.7.6; Evidence={ECO:0000255|HAMAP-Rule:MF_01321};
CC -!- SUBUNIT: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta'
CC and 1 omega subunit. When a sigma factor is associated with the core
CC the holoenzyme is formed, which can initiate transcription.
CC {ECO:0000255|HAMAP-Rule:MF_01321}.
CC -!- SIMILARITY: Belongs to the RNA polymerase beta chain family.
CC {ECO:0000255|HAMAP-Rule:MF_01321}.
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DR EMBL; CP000697; ABQ31153.1; -; Genomic_DNA.
DR RefSeq; WP_012039722.1; NC_009484.1.
DR AlphaFoldDB; A5FZX1; -.
DR SMR; A5FZX1; -.
DR STRING; 349163.Acry_1952; -.
DR PRIDE; A5FZX1; -.
DR EnsemblBacteria; ABQ31153; ABQ31153; Acry_1952.
DR KEGG; acr:Acry_1952; -.
DR eggNOG; COG0085; Bacteria.
DR HOGENOM; CLU_000524_4_0_5; -.
DR OMA; FMTWEGY; -.
DR OrthoDB; 9601at2; -.
DR Proteomes; UP000000245; Chromosome.
DR GO; GO:0000428; C:DNA-directed RNA polymerase complex; IEA:UniProtKB-KW.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-UniRule.
DR GO; GO:0003899; F:DNA-directed 5'-3' RNA polymerase activity; IEA:UniProtKB-UniRule.
DR GO; GO:0032549; F:ribonucleoside binding; IEA:InterPro.
DR GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-UniRule.
DR CDD; cd00653; RNA_pol_B_RPB2; 1.
DR Gene3D; 2.30.150.10; -; 1.
DR Gene3D; 2.40.270.10; -; 1.
DR Gene3D; 2.40.50.150; -; 1.
DR Gene3D; 3.90.1110.10; -; 1.
DR HAMAP; MF_01321; RNApol_bact_RpoB; 1.
DR InterPro; IPR042107; DNA-dir_RNA_pol_bsu_ext_1_sf.
DR InterPro; IPR019462; DNA-dir_RNA_pol_bsu_external_1.
DR InterPro; IPR015712; DNA-dir_RNA_pol_su2.
DR InterPro; IPR007120; DNA-dir_RNAP_su2_dom.
DR InterPro; IPR037033; DNA-dir_RNAP_su2_hyb_sf.
DR InterPro; IPR010243; RNA_pol_bsu_bac.
DR InterPro; IPR007121; RNA_pol_bsu_CS.
DR InterPro; IPR007644; RNA_pol_bsu_protrusion.
DR InterPro; IPR007642; RNA_pol_Rpb2_2.
DR InterPro; IPR037034; RNA_pol_Rpb2_2_sf.
DR InterPro; IPR007645; RNA_pol_Rpb2_3.
DR InterPro; IPR007641; RNA_pol_Rpb2_7.
DR InterPro; IPR014724; RNA_pol_RPB2_OB-fold.
DR PANTHER; PTHR20856; PTHR20856; 1.
DR Pfam; PF04563; RNA_pol_Rpb2_1; 1.
DR Pfam; PF04561; RNA_pol_Rpb2_2; 1.
DR Pfam; PF04565; RNA_pol_Rpb2_3; 1.
DR Pfam; PF10385; RNA_pol_Rpb2_45; 1.
DR Pfam; PF00562; RNA_pol_Rpb2_6; 1.
DR Pfam; PF04560; RNA_pol_Rpb2_7; 1.
DR TIGRFAMs; TIGR02013; rpoB; 1.
DR PROSITE; PS01166; RNA_POL_BETA; 1.
PE 3: Inferred from homology;
KW DNA-directed RNA polymerase; Nucleotidyltransferase; Reference proteome;
KW Transcription; Transferase.
FT CHAIN 1..1400
FT /note="DNA-directed RNA polymerase subunit beta"
FT /id="PRO_1000051959"
SQ SEQUENCE 1400 AA; 155923 MW; D0B0C69B7CA786B7 CRC64;
MNAISGGLNK VSFTNRKRIR KSFGRIPETT PMPNLIDVQR ASYDAFLQMH VSPDSRTNSG
LQEVFKSVFP IDDFAGRGRL EFVYYELEEP KYDVEECIQR GMTYAAPLKV VLRLIVWDVD
EDTGARSIRD IKEQPVYMGD MPLMTDNGTF VVNGTERVIV SQMHRSPGVF FDHDKGKTHS
SGKYLFAARV IPYRGSWLDF EFDAKDLIYV RIDRKRKLPV TTLLYALEGR ATEALRAARE
AKGESLEIGE IRGMDAEEIL TYFYGKVPFT RTRTRDGETA WARPFEPETF RGAKLVEDLV
DAETGEVVAK ADDKLTARVA RQIAVKTRTV LVSRADLIGR YVAEDLFDPN TGEIFADAGE
EISEAKLKTF EDAGLDEIPT LAIDQAKGPW IRNTLAADKN ASREDALIDI YRVIRPGEPP
TSETAEALFR GLFFDAERYD LSAVGRVKMN MRLGLECEDT VRVLRKEDIL RTIQIMCELK
DGRGQVDDID NLGNRRVRSV GELMENQYRI GLLRMERAIR ERMGSVDIDG VMPHDLINAK
PAAAAVREFF GSSQLSQFMD QTNPLSEVTH KRRLSALGPG GLTRERAGFE VRDVHPTHYG
RICPIETPEG PNIGLINSLA TFAKVNKYGF IETPYRLVKD GKVLDEYKYL SAMEEERLTV
AQADAPKLAD GTLTEDLVSV RRNGDFRLVK PDEVTAIDVS PRQLVSVAAA LIPFLENDDA
NRALMGSNMQ RQAVPLIKSD APLVGTGMEA PVARDSGATI VARRAGVIDQ IDGARIVVRA
TGEDGTTQGV DIYRLRKFMR SNQSTCINQR PLVRVGDRVG AGDIIADGPS TELGELALGR
NVLCAFMPWN GYNFEDSILI SERVAREDMF TSIHIEEFEV MARDTKLGQE EITRDIPNVG
EEALRNLDEA GIVYIGAEVN PGDILVGKVT PKGESPMTPE EKLLRAIFGE KASDVRDTSL
KLPPGVNGTV VDVRVFNRRG VDKDERALAI ERAEIERLAK DRDDERAIQE RAFLNRLREK
LLGQVAGSGY KGVRSGTEIT TELLAEIPRG AWRNLTVQDD RVMAEIETLK REFDASVHKL
QQRFESKVEK LQRGDEMPPG VMKMVKVFIA VKRKLQPGDK MAGRHGNKGV VSKVVPIEDM
PFLEDGTPVD VVLNPLGVPS RMNVGQILET HLGWACANLG RQIGEAVEAY QRDVAERERL
HAMLKSVYGE EIYNEQIASM SDAELRELCG NIRKGVPIAT PVFDGARITD IEDMLAKAGL
DVSGQMTVCD GRTGEQFERK VTVGYMYMLK LGHMVDDKIH ARSIGPYSLV TQQPLGGKAQ
FGGQRFGEME VWALEAYGAA YTLQEMLTVK SDDVSGRTKV YEAIVREQDN FEAGVPESFN
VLTKELKSLG LNVDLNLSVD
