ID   RPOB_ALBFT              Reviewed;        1370 AA.
AC   Q21SF7;
DT   11-SEP-2007, integrated into UniProtKB/Swiss-Prot.
DT   11-SEP-2007, sequence version 2.
DT   03-AUG-2022, entry version 87.
DE   RecName: Full=DNA-directed RNA polymerase subunit beta {ECO:0000255|HAMAP-Rule:MF_01321};
DE            Short=RNAP subunit beta {ECO:0000255|HAMAP-Rule:MF_01321};
DE            EC=2.7.7.6 {ECO:0000255|HAMAP-Rule:MF_01321};
DE   AltName: Full=RNA polymerase subunit beta {ECO:0000255|HAMAP-Rule:MF_01321};
DE   AltName: Full=Transcriptase subunit beta {ECO:0000255|HAMAP-Rule:MF_01321};
GN   Name=rpoB {ECO:0000255|HAMAP-Rule:MF_01321}; OrderedLocusNames=Rfer_3592;
OS   Albidiferax ferrireducens (strain ATCC BAA-621 / DSM 15236 / T118)
OS   (Rhodoferax ferrireducens).
OC   Bacteria; Proteobacteria; Betaproteobacteria; Burkholderiales;
OC   Comamonadaceae; Rhodoferax.
OX   NCBI_TaxID=338969;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC BAA-621 / DSM 15236 / T118;
RA   Copeland A., Lucas S., Lapidus A., Barry K., Detter J.C.,
RA   Glavina del Rio T., Hammon N., Israni S., Pitluck S., Brettin T., Bruce D.,
RA   Han C., Tapia R., Gilna P., Kiss H., Schmutz J., Larimer F., Land M.,
RA   Kyrpides N., Ivanova N., Richardson P.;
RT   "Complete sequence of chromosome of Rhodoferax ferrireducens DSM 15236.";
RL   Submitted (FEB-2006) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: DNA-dependent RNA polymerase catalyzes the transcription of
CC       DNA into RNA using the four ribonucleoside triphosphates as substrates.
CC       {ECO:0000255|HAMAP-Rule:MF_01321}.
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=a ribonucleoside 5'-triphosphate + RNA(n) = diphosphate +
CC         RNA(n+1); Xref=Rhea:RHEA:21248, Rhea:RHEA-COMP:14527, Rhea:RHEA-
CC         COMP:17342, ChEBI:CHEBI:33019, ChEBI:CHEBI:61557, ChEBI:CHEBI:140395;
CC         EC=2.7.7.6; Evidence={ECO:0000255|HAMAP-Rule:MF_01321};
CC   -!- SUBUNIT: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta'
CC       and 1 omega subunit. When a sigma factor is associated with the core
CC       the holoenzyme is formed, which can initiate transcription.
CC       {ECO:0000255|HAMAP-Rule:MF_01321}.
CC   -!- SIMILARITY: Belongs to the RNA polymerase beta chain family.
CC       {ECO:0000255|HAMAP-Rule:MF_01321}.
CC   -!- SEQUENCE CAUTION:
CC       Sequence=ABD71296.1; Type=Erroneous initiation; Evidence={ECO:0000305};
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DR   EMBL; CP000267; ABD71296.1; ALT_INIT; Genomic_DNA.
DR   RefSeq; WP_041790955.1; NC_007908.1.
DR   AlphaFoldDB; Q21SF7; -.
DR   SMR; Q21SF7; -.
DR   STRING; 338969.Rfer_3592; -.
DR   PRIDE; Q21SF7; -.
DR   EnsemblBacteria; ABD71296; ABD71296; Rfer_3592.
DR   KEGG; rfr:Rfer_3592; -.
DR   eggNOG; COG0085; Bacteria.
DR   HOGENOM; CLU_000524_4_0_4; -.
DR   OrthoDB; 9601at2; -.
DR   Proteomes; UP000008332; Chromosome.
DR   GO; GO:0000428; C:DNA-directed RNA polymerase complex; IEA:UniProtKB-KW.
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-UniRule.
DR   GO; GO:0003899; F:DNA-directed 5'-3' RNA polymerase activity; IEA:UniProtKB-UniRule.
DR   GO; GO:0032549; F:ribonucleoside binding; IEA:InterPro.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-UniRule.
DR   CDD; cd00653; RNA_pol_B_RPB2; 1.
DR   Gene3D; 2.30.150.10; -; 1.
DR   Gene3D; 2.40.270.10; -; 1.
DR   Gene3D; 2.40.50.150; -; 1.
DR   Gene3D; 3.90.1110.10; -; 1.
DR   HAMAP; MF_01321; RNApol_bact_RpoB; 1.
DR   InterPro; IPR042107; DNA-dir_RNA_pol_bsu_ext_1_sf.
DR   InterPro; IPR019462; DNA-dir_RNA_pol_bsu_external_1.
DR   InterPro; IPR015712; DNA-dir_RNA_pol_su2.
DR   InterPro; IPR007120; DNA-dir_RNAP_su2_dom.
DR   InterPro; IPR037033; DNA-dir_RNAP_su2_hyb_sf.
DR   InterPro; IPR010243; RNA_pol_bsu_bac.
DR   InterPro; IPR007121; RNA_pol_bsu_CS.
DR   InterPro; IPR007644; RNA_pol_bsu_protrusion.
DR   InterPro; IPR007642; RNA_pol_Rpb2_2.
DR   InterPro; IPR037034; RNA_pol_Rpb2_2_sf.
DR   InterPro; IPR007645; RNA_pol_Rpb2_3.
DR   InterPro; IPR007641; RNA_pol_Rpb2_7.
DR   InterPro; IPR014724; RNA_pol_RPB2_OB-fold.
DR   PANTHER; PTHR20856; PTHR20856; 1.
DR   Pfam; PF04563; RNA_pol_Rpb2_1; 1.
DR   Pfam; PF04561; RNA_pol_Rpb2_2; 2.
DR   Pfam; PF04565; RNA_pol_Rpb2_3; 1.
DR   Pfam; PF10385; RNA_pol_Rpb2_45; 1.
DR   Pfam; PF00562; RNA_pol_Rpb2_6; 1.
DR   Pfam; PF04560; RNA_pol_Rpb2_7; 1.
DR   TIGRFAMs; TIGR02013; rpoB; 1.
DR   PROSITE; PS01166; RNA_POL_BETA; 1.
PE   3: Inferred from homology;
KW   DNA-directed RNA polymerase; Nucleotidyltransferase; Reference proteome;
KW   Transcription; Transferase.
FT   CHAIN           1..1370
FT                   /note="DNA-directed RNA polymerase subunit beta"
FT                   /id="PRO_0000300386"
SQ   SEQUENCE   1370 AA;  152755 MW;  E0CDA6317D83FD5F CRC64;
     MAYSYTERKR IRKNFGSRDS VLEIPYLLQM QKDAYTAFLQ ADVHPKKRTA EGLQAAFEAA
     FPIISHNGFV EMKYLEYNLA KPAFDVRECQ TRGLTFASAV RAKVQLFIYD RESSTSQNKV
     IKEVKEQEVY MGEVPLMTTK GSFIINGTER VIVSQLHRSP GVFFEHDKGK THSSGKLLFS
     ARIIPYRGSW LDFEFDPKDF LYFRVDRRRK MPVTILLKAI GLNHESILAN FFVNDNFRLM
     DSGAQMEFVA ERLRGEVARF DITDKSGKVI VAKEKRVTAR HTRELEQSGT THISVPEDFL
     LGRVVARNIV DTDTGEILAK ANEELTEALI KKLRLAGVQD LPCIYTNELD QGAYISQTLR
     SDETVDEFAA RVAIYRMMRP GEPPTEDAVQ ALFQRLFYNP DTYDLSRVGR MKFNAKMGRP
     ESTGPMVLTN EDILAVVKIL VDLRNGRGDV DDIDHLGNRR VRCVGELAEN QYRTGLARIE
     KAVKERLGQA EQEPLMPHDL INSKPISAAL KEFFGASQLS QFMDQTNPLS EITHKRRVSA
     LGPGGLTRER AGFEVRDVHV THYGRVCPIE TPEGPNIGLI NSLALYARLN DYGFIETPYR
     RVVDGKVTME IDYLSAIEEG KFVIAQANAV LDKDGKLTGE MISAREAGET IFAGPERVQY
     MDVSPAQIVS VAASLVPFLE HDDANRALMG ANMSRQAVPI LRPEKPMVGT GIERVAAIDS
     GTVVTATRGG MVDYVDATRV VIRVNDDEAQ AGEVGVDIYN LIKYQRSNQN TNIHQRPIVK
     KGDMLAKGDV IADGASTDLG ELALGQNMLI GFMTWNGYNF EDSILISERV VADDRYTSIH
     IEELVVMARD TKLGCEEITR DIPNLSEQQL NRLDESGIIY VGAEVQPGDT LVGKVTPKGE
     TTLTPEEKLL RAIFGEKASD VKDTSLRVDQ GSQGTVIDVQ VFTREGIVRD RRAQQIIDDE
     LKRFRLDLND QLRLVEADSF DRIEKLLVGK VANGGPQKLA KGTTIDKAYL TSVEKHHWFD
     IRPAEDDVAA QLESIKNSME QTRHSFDLAF EEKRKKLTQG DELPAGVLKM VKVYLAVKRH
     LQPGDKMAGR HGNKGVVSKI VPVEDMPFMA DGTPCDIVLN PLGVPSRMNI GQVLEVHLGW
     AAKGIGQRIG DMLQAEAKVA ELRKFLDELY NGTGRKEDLA QLSDDEVLEM AGNLTSGVPF
     ATPVFDGASE ADIGAMLKLA YPEDAIRQKG LTPARTQAYL YDGRTGDPFE RPTTIGYMHY
     LKLHHLVDDK MHARSTGPYS LVTQQPLGGK AQFGGQRFGE MEVWALEAYG AAYTLQEMLT
     VKSDDVQGRT KVYESIVKGE HSIEAGMPES FNVLVKEIRS LGIDIELERG