RPOB_ALIB4
ID RPOB_ALIB4 Reviewed; 1382 AA.
AC A8EVZ4;
DT 08-APR-2008, integrated into UniProtKB/Swiss-Prot.
DT 13-NOV-2007, sequence version 1.
DT 03-AUG-2022, entry version 78.
DE RecName: Full=DNA-directed RNA polymerase subunit beta {ECO:0000255|HAMAP-Rule:MF_01321};
DE Short=RNAP subunit beta {ECO:0000255|HAMAP-Rule:MF_01321};
DE EC=2.7.7.6 {ECO:0000255|HAMAP-Rule:MF_01321};
DE AltName: Full=RNA polymerase subunit beta {ECO:0000255|HAMAP-Rule:MF_01321};
DE AltName: Full=Transcriptase subunit beta {ECO:0000255|HAMAP-Rule:MF_01321};
GN Name=rpoB {ECO:0000255|HAMAP-Rule:MF_01321}; OrderedLocusNames=Abu_1884;
OS Aliarcobacter butzleri (strain RM4018) (Arcobacter butzleri).
OC Bacteria; Proteobacteria; Epsilonproteobacteria; Campylobacterales;
OC Arcobacteraceae; Aliarcobacter.
OX NCBI_TaxID=367737;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=RM4018;
RX PubMed=18159241; DOI=10.1371/journal.pone.0001358;
RA Miller W.G., Parker C.T., Rubenfield M., Mendz G.L., Woesten M.M.S.M.,
RA Ussery D.W., Stolz J.F., Binnewies T.T., Hallin P.F., Wang G., Malek J.A.,
RA Rogosin A., Stanker L.H., Mandrell R.E.;
RT "The complete genome sequence and analysis of the Epsilonproteobacterium
RT Arcobacter butzleri.";
RL PLoS ONE 2:E1358-E1358(2007).
CC -!- FUNCTION: DNA-dependent RNA polymerase catalyzes the transcription of
CC DNA into RNA using the four ribonucleoside triphosphates as substrates.
CC {ECO:0000255|HAMAP-Rule:MF_01321}.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=a ribonucleoside 5'-triphosphate + RNA(n) = diphosphate +
CC RNA(n+1); Xref=Rhea:RHEA:21248, Rhea:RHEA-COMP:14527, Rhea:RHEA-
CC COMP:17342, ChEBI:CHEBI:33019, ChEBI:CHEBI:61557, ChEBI:CHEBI:140395;
CC EC=2.7.7.6; Evidence={ECO:0000255|HAMAP-Rule:MF_01321};
CC -!- SUBUNIT: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta'
CC and 1 omega subunit. When a sigma factor is associated with the core
CC the holoenzyme is formed, which can initiate transcription.
CC {ECO:0000255|HAMAP-Rule:MF_01321}.
CC -!- SIMILARITY: Belongs to the RNA polymerase beta chain family.
CC {ECO:0000255|HAMAP-Rule:MF_01321}.
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DR EMBL; CP000361; ABV68117.1; -; Genomic_DNA.
DR RefSeq; WP_004511254.1; NC_009850.1.
DR AlphaFoldDB; A8EVZ4; -.
DR SMR; A8EVZ4; -.
DR STRING; 367737.Abu_1884; -.
DR EnsemblBacteria; ABV68117; ABV68117; Abu_1884.
DR KEGG; abu:Abu_1884; -.
DR eggNOG; COG0085; Bacteria.
DR HOGENOM; CLU_000524_4_0_7; -.
DR OMA; FMTWEGY; -.
DR OrthoDB; 9601at2; -.
DR Proteomes; UP000001136; Chromosome.
DR GO; GO:0000428; C:DNA-directed RNA polymerase complex; IEA:UniProtKB-KW.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-UniRule.
DR GO; GO:0003899; F:DNA-directed 5'-3' RNA polymerase activity; IEA:UniProtKB-UniRule.
DR GO; GO:0032549; F:ribonucleoside binding; IEA:InterPro.
DR GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-UniRule.
DR CDD; cd00653; RNA_pol_B_RPB2; 1.
DR Gene3D; 2.40.270.10; -; 2.
DR Gene3D; 2.40.50.150; -; 1.
DR Gene3D; 3.90.1110.10; -; 1.
DR HAMAP; MF_01321; RNApol_bact_RpoB; 1.
DR InterPro; IPR019462; DNA-dir_RNA_pol_bsu_external_1.
DR InterPro; IPR015712; DNA-dir_RNA_pol_su2.
DR InterPro; IPR007120; DNA-dir_RNAP_su2_dom.
DR InterPro; IPR037033; DNA-dir_RNAP_su2_hyb_sf.
DR InterPro; IPR010243; RNA_pol_bsu_bac.
DR InterPro; IPR007121; RNA_pol_bsu_CS.
DR InterPro; IPR007644; RNA_pol_bsu_protrusion.
DR InterPro; IPR007642; RNA_pol_Rpb2_2.
DR InterPro; IPR037034; RNA_pol_Rpb2_2_sf.
DR InterPro; IPR007645; RNA_pol_Rpb2_3.
DR InterPro; IPR007641; RNA_pol_Rpb2_7.
DR InterPro; IPR014724; RNA_pol_RPB2_OB-fold.
DR PANTHER; PTHR20856; PTHR20856; 1.
DR Pfam; PF04563; RNA_pol_Rpb2_1; 1.
DR Pfam; PF04561; RNA_pol_Rpb2_2; 2.
DR Pfam; PF04565; RNA_pol_Rpb2_3; 1.
DR Pfam; PF10385; RNA_pol_Rpb2_45; 1.
DR Pfam; PF00562; RNA_pol_Rpb2_6; 1.
DR Pfam; PF04560; RNA_pol_Rpb2_7; 1.
DR TIGRFAMs; TIGR02013; rpoB; 1.
DR PROSITE; PS01166; RNA_POL_BETA; 1.
PE 3: Inferred from homology;
KW DNA-directed RNA polymerase; Nucleotidyltransferase; Reference proteome;
KW Transcription; Transferase.
FT CHAIN 1..1382
FT /note="DNA-directed RNA polymerase subunit beta"
FT /id="PRO_0000329163"
SQ SEQUENCE 1382 AA; 155153 MW; FC061880C4E1D78B CRC64;
MLNSLKSGNR LRVDFAKNPQ KIEIPNLLQL QQTSYDTFLM IGQEDRTTAG IEKVFKSIFP
IHDVQNRLTL DYLGSEVGKP KYDVRESMVR GLTYSIPLKI NIRLTLWDLD EKTGEKIGVK
DMKEQSLFIR EIPLMTDRTS FIVNGVERVV VNQLHRSPGV IFKEEESNTA DNKLIYTGQI
IPDRGSWLYF EYDSKDVLYV RINKRRKVPV TILFRALGYS KEDIIKLFYP IVNIKIKNNK
FLTEFNPDDF MGRIEFDVKD DKGNLVIGAG KRLTARKAKA LIEGGLKLIE YPLELLMDRS
TANTIYDPES GEVLFDALTN LDELKLKKLL DLGFESFDIA NDLAVGIDAS IINAFKADAE
SLKLLKQTEQ IDDENDLAAI RIYKVMRPGE PVTKEAAKDF VKKLFFDPER YDLTKVGRMK
MNHKLGVNVP EYVTTLTYED VIKTVQYLVK VKSGHGHIDD RDHLGNRRIR AIGELLANEL
HAGLIKMQKA IRDKMTTLSG TLEDLMPHDL VNSKMITSTI TEFFTSGQLS QFMDQTNPLS
EVTHKRRLSA LGEGGLVKER AGFEVRDVHP THYGRICPVE TPEGQNIGLI NTLSTFSKVN
DLGFIEAPYK KVVDGVVTNE ISYYTATQEE GLVIAPGSTK VDENGKIIEP LIEVRKNGEI
LLMERNSVDL IDISSQMVMG VAASLIPFLE HDDANRALMG SNMMRQAVPL LRPSAPVVGT
GLEKIVARDA WEAIKANRAG LVEKADAKNI YIRGEDENGA FIDHYTVNKN VRTNNNTSFG
QRIAVKEGDF VQKGQVIADG PSMDKGELAV GINAMVAFMP WNGYNYEDAI ILSERLIEED
AFTSVHIYEK EIECRELKHG NEEITRDLPG VKEESISHLD NSGIVKVGTY VTPGMILVGK
VTPKGEIKPT PEERLLRAIF GEKAGHVINK SLVCPTSMEG TVVDVKVFTK KGYEKDDRAV
AEIESEKAEL DLKHHDKLLM LDREEILKIN DLLLKATLTK DVELDDVVYK KGETIPVDVL
NNVNRFAMKK VVSSYSKEIE KAYNDIKEYF IKQKAHLREE HEEKLQILEH DDILSSGVIK
QVKVYIATKR KIKVGDKMAG RHGNKGIVSN IVPKVDMPYL EDGTTVDVIL NPLGVPSRMN
IGQILEVHLG LAGKKLGNQI QDIFEAKRAD FIAELRAKMT EIASVAKLMN GKAFMDSLND
EELVQYAQDW AKGVRFATQI FDGVKAEEFA KLFELAKIDS DGKCVLFDGK TGEKMKERVN
VGYMYMLKLH HLVDEKVHAR STGPYSLVTQ QPVGGKALFG GQRFGEMEVW ALEAYGATNV
LKEMLTTKSD DVEGRTKAYR AIANGENVPN SGVPETFFVL TKELKALALD VEIFGEVENN
EQ
